Citations 1
The Volume-Outcome Effect Calls for Centralization of Care in Esophageal Adenocarcinoma: Results From a Large National Cancer Registry
Han, Samuel , Hosokawa, Patrick , Friedman, Chloe , Fox, Charlie, Scott, Frank I. , Vajravelu, Ravy K. , McCarter, Martin D. , Cook, Michael B. , Gleisner, Ana , Katzka, David A. , Wani, Sachin , Kolb, Jennifer M. , Lieu, Christopher H. , Murphy, Caitlin C. , Falk, Gary W. , Scott, Frank I
American Journal of Gastroenterology | November 23, 2020 | Volume: 116 | Issue: 4 | Pages: 811-815
INTRODUCTION: Using the National Cancer Database, we assessed the relationship between facility overall esophageal adenocarcinoma (EAC) case volume and survival. METHODS: We categorized facilities into volume quintiles based on annual EAC patient volume and performed a multivariable Cox proportional hazards regression between facility patient volume and survival. RESULTS: In a cohort of 116,675 patients, facilities with higher vs lower (≥25 vs 1–4 cases) annual EAC patient volume demonstrated improved survival (adjusted hazard ratio: 0.80. 95% confidence interval: 0.70–0.91). DISCUSSION: This robust volume-outcome effect calls for centralization of care for EAC patients at high annual case volume facilities.