Citations 2
Letter: An International Investigation Into the COVID-19 Pandemic and Workforce Depletion in Highly Specialized Neurointerventional Units – Insights From Stroke Thrombectomy and Aneurysm Registry and Endovascular Neurosurgery Research Group
Alawieh, Ali , Kasab, Sami Al , Almallouhi, Eyad , Levitt, Michael R. , Jabbour, Pascal , Sweid, Ahmad , Starke, Robert M. , Wolfe, Stacey Q , Fragata, Isabel , Maier, Ilko , Matouk, Charles, Howard, Brian M. , Grossberg, Jonathan A , Cawley, M. F., Kan, Peter , Hafeez, Muhammad Ubaid , Singer, Justin, Crowley, R. Webster , Joshi, Krishna C. , Brinjikji, Waleed , Ogilvy, Christopher S. , Gomez‐Paz, Santiago , Veznedaroglu, Erol, Binning, Mandy J., Soomro, Jazba , Williamson, Richard , Chalhoub, Reda , Crosa, Roberto , Webb, Sharon, Psychogios, Marios, Ducruet, Andrew F. , Albuquerque, Felipe C. , Turner, Raymond, Casagrande, Walter, Leacy, Reade De , Fessler, Richard D., Osanai, Toshiya , Chowdhry, Shakeel , Schirmer, Clemens M. , Ringer, Andrew J. , Spiotta, Alejandro M , collaborators, STAR and ENRG, Savastano, Luis E., Gomez-Paz, Santiago , Crosa, Roberto , Levitt, Michael R , De Leacy, Reade , Schirmer, Clemens M , Almallouhi, Eyad , Hafeez, Muhammad U , Wolfe, Stacey Quintero , Fragata, Isabel , Howard, Brian M , Alawieh, Ali M , Ogilvy, Christopher S , Jabbour, Pascal , Saini, Vasu A , Fargen, Kyle M , Arthur, Adam Stephen , Goyal, Nitin , Cawley, Michael, Savastano, Luis , Levy, Elad I. , Waqas, Muhammad, Mokin, Maxim , Mascitelli, Justin R , Yoo, Albert J. , Grande, Andrew Walker , Psychogios, Marios‐Nikos , Majmundar, Neil J. , Al‐Mufti, Fawaz , Mocco, J , Park, Minhee , collaborators, STAR and ENRG
Neurosurgery | August 24, 2020 | Volume: 87 | Issue: 6 | Pages: E697-E699
Effect of Anatomic Segment Involvement on Stereotactic Radiosurgery for Facial Nerve Schwannomas: An International Multicenter Cohort Study
Mehta, Gautam U. , Leković, Gregory P. , Slattery, William H. , Brackmann, Derald E., Long, Hao , Kano, Hideyuki , Mureb, Monica , Bernstein, Kenneth , Langlois, Anne-Marie, Mathieu, David , Nabeel, Ahmed M. , Reda, Wael A. , Tawadros, Sameh R. , Abdelkarim, Khaled , El-Shehaby, Amr M. N. , Emad, Reem M. , Mohammed, Nasser , Urgošík, Dušan, Liščák, Roman , Lee, Cheng‐Chia , Montazeripouragha, Amanallah , Joshi, Krishna C. , Barnett, Gene H. , Lunsford, L. Dade , Sheehan, Jason P. , Mehta, Gautam U , Mathieu, David , Kondziolka, Douglas , Langlois, Anne-Marie, Reda, Wael A. , Yang, Huai‐Che , Kaufmann, Anthony M. , Trifiletti, Daniel M.
Neurosurgery | June 19, 2020 | Volume: 88 | Issue: 1 | Pages: E91-E98
Abstract BACKGROUND Facial nerve schwannomas are rare, challenging tumors to manage due to their nerve of origin. Functional outcomes after stereotactic radiosurgery (SRS) are incompletely defined. OBJECTIVE To analyze the effect of facial nerve segment involvement on functional outcome for these tumors. METHODS Patients who underwent single-session SRS for facial nerve schwannomas with at least 3 mo follow-up at 11 participating centers were included. Preoperative and treatment variables were recorded. Outcome measures included radiological tumor response and neurological function. RESULTS A total of 63 patients (34 females) were included in the present study. In total, 75% had preoperative facial weakness. Mean tumor volume and margin dose were 2.0 ± 2.4 cm 3 and 12.2 ± 0.54 Gy, respectively. Mean radiological follow-up was 45.5 ± 38.9 mo. Progression-free survival at 2, 5, and 10 yr was 98.1%, 87.2%, and 87.2%, respectively. The cumulative proportion of patients with regressing tumors at 2, 5, and 10 yr was 43.1%, 63.6%, and 63.6%, respectively. The number of involved facial nerve segments significantly predicted tumor progression ( P = .04). Facial nerve function was stable or improved in 57 patients (90%). Patients with involvement of the labyrinthine segment of the facial nerve were significantly more likely to have an improvement in facial nerve function after SRS ( P = .03). Hearing worsened in at least 6% of patients. Otherwise, adverse radiation effects included facial twitching (3 patients), facial numbness (2 patients), and dizziness (2 patients). CONCLUSION SRS for facial nerve schwannomas is effective and spares facial nerve function in most patients. Some patients may have functional improvement after treatment, particularly if the labyrinthine segment is involved.