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Waugh, Jeff L.

https://orcid.org/0000-0001-7526-1342

Mayo Clinic

The University of Texas Southwestern Medical Center

Citations 3

Management of Infantile Spasms During the COVID-19 Pandemic
Mytinger, John R. , Baumer, Fiona M. , Ciliberto, Michael A. , Cohen, Bruce H. , Dlugos, Dennis , Harini, Chellamani , Joshi, Sucheta M. , Keator, Cynthia, McGoldrick, Patricia E. , Nickels, Katherine , Park, Jun , Pasupuleti, Archana, Shahid, Asim, Shellhaas, Renée A. , Shrey, Daniel W. , Singh, Rani K. , Yozawitz, Elissa , Yuskaitis, Christopher J. , Waugh, Jeff L. , Baumer, Fiona M , Park, Jun T , Patel, Anup D , Singh, Rani K , Pearl, Phillip L , Shellhaas, Renée A , Yozawitz, Elissa G , Nickels, Katherine C , Grinspan, Zachary M. , Hussain, Shaun A. , Knupp, Kelly G. , Patel, Anup D. , Wolf, Steven M. , Pearl, Phillip L.

Journal of Child Neurology | June 24, 2020 | Volume: 35 | Issue: 12 | Pages: 828-834

10.1177/0883073820933739 Get It

Circumstances of the COVID-19 pandemic have mandated a change to standard management of infantile spasms. On April 6, 2020, the Child Neurology Society issued an online statement of immediate recommendations to streamline diagnosis and treatment of infantile spasms with utilization of telemedicine, outpatient studies, and selection of first-line oral therapies as initial treatment. The rationale for the recommendations and specific guidance including follow-up assessment are provided in this manuscript. These recommendations are indicated as enduring if intended to outlast the pandemic, and limited if intended only for the pandemic health care crisis but may be applicable to future disruptions of health care delivery.
Advanced MRI techniques for transcranial high intensity focused ultrasound targeting
Shah, Bhavya , Blezek, Daniel J. , Waugh, Jeff L. , Imphean, Darren , Yu, Frank , Patel, Toral , Chitnis, Shilpa , Dewey, Richard B. , Lehman, Vance T. , Blezek, Daniel, Kaufmann, Timothy J. , Maldjian, Joseph A. , Chopra, Rajiv , Patel, Toral R

Brain | March 18, 2020 | Volume: 143 | Issue: 9 | Pages: 2664-2672

10.1093/brain/awaa107 Get It

Abstract Magnetic resonance guided high intensity focused ultrasound is a novel, non-invasive, image-guided procedure that is able to ablate intracranial tissue with submillimetre precision. It is currently FDA approved for essential tremor and tremor dominant Parkinson’s disease. The aim of this update is to review the limitations of current landmark-based targeting techniques of the ventral intermediate nucleus and demonstrate the role of emerging imaging techniques that are relevant for both magnetic resonance guided high intensity focused ultrasound and deep brain stimulation. A significant limitation of standard MRI sequences is that the ventral intermediate nucleus, dentatorubrothalamic tract, and other deep brain nuclei cannot be clearly identified. This paper provides original, annotated images demarcating the ventral intermediate nucleus, dentatorubrothalamic tract, and other deep brain nuclei on advanced MRI sequences such as fast grey matter acquisition T1 inversion recovery, quantitative susceptibility mapping, susceptibility weighted imaging, and diffusion tensor imaging tractography. Additionally, the paper reviews clinical efficacy of targeting with these novel MRI techniques when compared to current established landmark-based targeting techniques. The paper has widespread applicability to both deep brain stimulation and magnetic resonance guided high intensity focused ultrasound.