Citations 3
Patient-Centered Treatment of Chronic Migraine With Medication Overuse
Hentz, Joseph G. , Sahai‐Srivastava, Soma , Murinova, Natalia , Spare, Nicole , Treppendahl, Christina, Martin, Vincent T., Birlea, Marius , Digre, Kathleen B. , Leonard, Michael , Robert, Teri, Investigators, on behalf of the MOTS, Ahmed, Zubair , Bennett, Nathan, Blaya, Maike Tiede, Cutrer, Michael, David, Paru S., DeLange, Justin M., Goldstick, Lawrence, Harter, Christine, Hutchinson, Susan , Kennebeck, Greg, Lane, Judy, Mechtler, Laszlo , Monteith, Tesha, Mullally, William J. , O’Carroll, Cumara B. , Pippitt, Karly , Plato, Brian, Rau, Jill C. , Razzaghi, M., Schecht, Howard, True, David , Wald, John J., Monteith, Teshamae , Sahai-Srivastava, Soma , Spare, Nicole M, Digre, Kathleen, Monteith, Teshamae S , Schwedt, Todd J. , Watson, David George , Leonard, Michael, Dodick, David W. , Investigators, on behalf of the MOTS, Cortez, Melissa , Cutrer, Michael, Rizzoli, Paul B. , Smith, Tim
Neurology | February 15, 2022 | Volume: 98 | Issue: 14 | Pages: No page available
Determinants of pain interference and headache impact in patients who have chronic migraine with medication overuse: Results from the MOTS trial
Sahai‐Srivastava, Soma , Murinova, Natalia , Birlea, Marius , Ahmed, Zubair , Digre, Kathleen B. , Lopez, Kristina, Mullally, William J. , Blaya, Maike Tiede, Pippitt, Karly , Cutrer, F. Michael , DeLange, Justin M., Schecht, Howard, Lane, Judy, Wald, John J., Martin, Vincent T., Spare, Nicole , Hentz, Joseph G. , Robert, Teri, Investigators, on behalf of the MOTS, Pippitt, Karly , Sahai-Srivastava, Soma , Schwedt, Todd J. , Rizzoli, Paul B. , Cortez, Melissa , Dodick, David W. , Investigators, on behalf of the MOTS
Cephalalgia | May 3, 2021 | Volume: 41 | Issue: 10 | Pages: 1053-1064
Objective “Pain interference” and “headache impact” refer to negative consequences that pain and headache have on one’s life. This study investigated determinants of these negative impacts in a large patient cohort who have chronic migraine with medication overuse. Methods Six hundred and eleven adults were enrolled from 34 headache, neurology, and primary care clinics. Negative consequences of chronic migraine with medication overuse were determined using the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference 6b questionnaire and the Headache Impact Test 6. Relationships between PROMIS-6b and Headache Impact Test 6 scores with demographics, headache characteristics, medication use, anxiety symptoms, and depression symptoms were assessed with linear regression. Elastic Net regression was used to develop a multiple regression model. Results PROMIS-6b T-Scores averaged 65.2 (SD 5.4) and Headache Impact Test 6 scores averaged 65.0 (SD 5.3), indicating severe negative consequences of chronic migraine with medication overuse. Chronic migraine with medication overuse interfered with enjoyment of life, concentration, daily activities, doing tasks away from home, and socializing. Depression symptom severity had the strongest relationship with pain interference and headache impact. Moderate-to-severe headache frequency, headache intensity, and anxiety symptoms were also associated with pain interference and headache impact. Conclusions Chronic migraine with medication overuse is associated with substantial negative consequences, the extent of which is most strongly related to depression symptoms.
Field Test Results of Sex- and Gender-Specific Health Multimedia Case-Based Learning Modules
Casanova, Robert, Miller, Virginia M. , Cheon, Jongpil , Barron, Rebecca , Cannaday, Rania, Case, Gretchen A. , Digre, Kathleen B. , Jensen, Jani R., McGregor, Alyson J. , Pippitt, Karly , Davidge‐Pitts, Caroline , Pomeroy, Brian, Webster, Dan, Jenkins, Marjorie , Jensen, Jani, Davidge-Pitts, Caroline, Gilmore, Linda
Journal of Women's Health | August 2, 2019 | Volume: 28 | Issue: 12 | Pages: 1755-1761
Background: The sex- and gender-specific health (SGSH) multimedia case-based learning modules (MCBLMs) were developed to address the absence of validated or peer-reviewed material that incorporates topics of sex and gender differences into medical curricula. This article provides the methodology for development of the modules and reports the results of a field test of the modules in different medical educational settings. Methods: MCBLMs were created by a multidisciplinary committee of scientists, health profession educators, and students. Two modules, osteoporosis and diabetes, were tested in various settings based on the curricular needs at each of the five accredited institutions. Each module consisted of a pretest and three interactive, multimedia stand-alone sections with post-tests. Scores on the tests were compared using a paired-samples t -test. A postmodule survey was used to evaluate the format. Results: Four hundred eighteen students participated in the field testing. For the 194 who completed the osteoporosis module, the post-test scores (M = 13.71, standard deviation [SD] = 2.09) were significantly higher than the pretest scores (M = 10.54, SD = 2.41), p < 0.001. Post-test scores for the 285 who completed the diabetes module (M = 16.55, SD = 2.46) were also significantly higher than the pretest scores (M = 13.71, SD = 2.09), p < 0.001. The postmodule survey showed positive acceptance of the format with an average score of 3.54/4 for osteoporosis and 3.45/4 for diabetes. Conclusion: The SGSH MCBLM field testing results show that the modules have a positive effect on content knowledge in multiple settings and are well accepted by learners.