Citations 1
PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury
Takahata, Keisuke , Kimura, Yasuyuki , Koga, Shunsuke , Ichise, Masanori , Saito, Fumie, Moriguchi, Sho , Kitamura, Soichiro , Kubota, Manabu , Umeda, Satoshi , Niwa, Fumitoshi , Mizushima, Jin, Morimoto, Yoko, Funayama, Michitaka , Tabuchi, Hajime , Bieniek, Kevin F. , Kawamura, Kazunori , Zhang, Ming-Rong, Mimura, Masaru , Kato, Motoichiro, Suhara, Tetsuya , Higuchi, Makoto , Koga, Shunsuke , Sahara, Naruhiko , Shimada, Hitoshi , Morimoto, Yoko, Dickson, Dennis W.
Brain | July 24, 2019 | Volume: 142 | Issue: 10 | Pages: 3265-3279
Is tau load associated with long-term outcomes of TBI? By using PET to assess tau deposits in patients with chronic TBI, Takahata et al. reveal elevated tau load compared to age-matched controls, and show that the abundance of tau in white matter is associated with late-onset neuropsychiatric symptoms.