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1 citation(s) found for "Zwijsen, An".

A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression
Khurana, Satish , Buckley, Shannon M. , Schouteden, Sarah, Ekker, Stephen C. , Petryk, Anna , Delforge, Michel, Zwijsen, An , Verfaillie, Catherine M. , Ekker, Stephen C , Verfaillie, Catherine

Mayo Clinic

Blood | December 14, 2012 | Volume: 121 | Issue: 5 | Pages: 781-790

10.1182/blood-2012-07-446443 | PMID 23243277 Get It

Key PointsCytokine-induced loss of murine as well as human HSPC homing during ex vivo culture can be prevented by addition of BMP4. In HSPCs, BMP4 directly regulates Integrin-α4 expression through SMAD-independent p38 MAPK-mediated signaling.