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130 citation(s) found for "McDade, Eric".

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers
Gordon, Brian A. , Blazey, Tyler , Christensen, Jon, Dincer, Aylin , Flores, Shaney , Keefe, Sarah , Wang, Guoqiao , Hassenstab, Jason , Aschenbrenner, Andrew J. , Hornbeck, Russ C. , Jack, Clifford R. , Berman, Sarah , Brosch, Jared R. , Gauthier, Serge , Dyck, Christopher H. van , Mintun, Mark A., Klein, Gregory , Cairns, Nigel J., Marcus, Daniel S. , Raichle, Marcus E. , Morris, John C. , Bateman, Randall J. , Benzinger, Tammie L.S. , Jack, Clifford R , Gordon, Brian A , Bateman, Randall J , Chen, Charles D , Benzinger, Tammie L S , Hassenstab, Jason , Morris, John C , Aschenbrenner, Andrew J , Chen, Charles , Su, Yi , McDade, Eric , Li, Yan , Ances, Beau M. , Galasko, Douglas , Lah, James J. , Masellis, Mario , Ristic, Smiljana, Xiong, Chengjie , Holtzman, David M. , Berman, Sarah

Mayo Clinic

Brain | January 29, 2019 | Volume: 142 | Issue: 4 | Pages: 1063-1076

10.1093/brain/awz019 | PMID 30753379 Get It

O3‐13‐03: THE RELATIONSHIP BETWEEN TAU PET AND OTHER AD BIOMARKERS IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE
Christensen, Jon, Dincer, Aylin , Keefe, Sarah , Wang, Guoqiao , Raichle, Marcus E. , Koeppe, Bob, Network, Dominantly Inherited Alzheimer's, Gordon, Brian A. , Blazey, Tyler , Flores, Shaney , McDade, Eric , Jack, Clifford R. , Morris, John C. , Bateman, Randall J. , Benzinger, Tammie L.S. , Network, Dominantly Inherited Alzheimer's

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_19 | Pages: No page available

10.1016/j.jalz.2018.06.2845 Get It

O1‐02‐03: DIAN‐TU ADAPTIVE PREVENTION TRIAL LAUNCH AND BASELINE DATA
Santacruz, Anna , Farlow, Martin R. , Salloway, Stephen , Fagan, Anne M. , Wang, Guoqiao , Koeppe, Bob, Martényi, Ferenc, Yaari, R. , Siemers, Eric , Clifford, David B. , Bateman, Randall J. , Mills, Susan, Morris, John C. , Benzinger, Tammie L.S. , Goate, Alison , Hassenstab, Jason , Xiong, Chengjie , Jack, Clifford R. , Searle, Alison, McDade, Eric

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_3 | Pages: No page available

10.1016/j.jalz.2018.06.2338 Get It

IC‐P‐204: THE RELATIONSHIP BETWEEN TAU PET AND OTHER AD BIOMARKERS IN AUTOSOMAL DOMINANT ALZHEIMER DISEASE
Christensen, Jon, Dincer, Aylin , Keefe, Sarah , Wang, Guoqiao , Raichle, Marcus E. , Koeppe, Bob, Network, Dominantly Inherited Alzheimer's, Gordon, Brian A. , Blazey, Tyler , Flores, Shaney , McDade, Eric , Jack, Clifford R. , Morris, John C. , Bateman, Randall J. , Benzinger, Tammie L.S. , Network, Dominantly Inherited Alzheimer's

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_3 | Pages: No page available

10.1016/j.jalz.2018.06.2271 Get It

IC‐P‐165: ROBUST IDENTIFICATION OF BRAIN STRUCTURES MOST DISCRIMINATIVE IN DETECTING EARLY CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE
Veale, Thomas , Altmann, André , Network, Dominantly Inherited Alzheimer, Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C. , Cash, David M. , Modat, Marc , Network, Dominantly Inherited Alzheimer

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_2 | Pages: No page available

10.1016/j.jalz.2018.06.2232 Get It

IC‐P‐048: SAMPLE SIZE ESTIMATES FOR SECONDARY PREVENTION STUDIES USING REGIONAL ATROPHY RATES
Veale, Thomas , Poole, Teresa, Network, Dominantly Inherited Alzheimer, Cash, David M. , Modat, Marc , Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Bateman, Randall J. , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Frost, Chris , Fox, Nick C. , Network, Dominantly Inherited Alzheimer

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_1 | Pages: No page available

10.1016/j.jalz.2018.06.2112 Get It

P2‐438: ROBUST IDENTIFICATION OF BRAIN STRUCTURES MOST DISCRIMINATIVE IN DETECTING EARLY CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE
Veale, Thomas , Altmann, André , (DIAN), Dominantly Inherited Alzheimer Network, Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Fox, Nick C. , Cash, David M. , Modat, Marc , (DIAN), Dominantly Inherited Alzheimer Network

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_16 | Pages: No page available

10.1016/j.jalz.2018.06.1130 Get It

P1‐410: SAMPLE SIZE ESTIMATES FOR SECONDARY PREVENTION STUDIES USING REGIONAL ATROPHY RATES
Veale, Thomas , Poole, Teresa, (DIAN), Dominantly Inherited Alzheimer Network, Cash, David M. , Modat, Marc , Molteni, Erika , Cardoso, M. Jorge , Benzinger, Tammie L.S. , Jack, Clifford R. , McDade, Eric , Bateman, Randall J. , Morris, John C. , Rossor, Martin N. , Ourselin, Sébastien , Frost, Chris , Fox, Nick C. , (DIAN), Dominantly Inherited Alzheimer Network

Mayo Clinic

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.419 Get It

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease
Joseph‐Mathurin, Nelly , Jasielec, Mateusz S., Vlassenko, Andrei G. , Gordon, Brian A. , Hornbeck, Russ C. , Cash, Lisa, Veale, Thomas , Cash, David M. , Buckles, Virginia, Cairns, Nigel J. , Goate, Alison , Karch, Celeste M. , Klunk, William E. , Marcus, Daniel S. , Mayeux, Richard , Noble, James M. , Ringman, John M. , Xiong, Chengjie , Morris, John C. , Bateman, Randall J. , Network, Dominantly Inherited Alzheimer, Gordon, Brian A , Bateman, Randall J , Joseph-Mathurin, Nelly , Karch, Celeste M , Morris, John C , Cash, David M , Su, Yi , Blazey, Tyler , Friedrichsen, Karl A. , Ances, Beau M. , Brickman, Adam M. , Cruchaga, Carlos , Jack, Clifford R. , Koeppe, Robert A. , McDade, Eric , Saykin, Andrew J. , Thompson, Paul M. , Benzinger, Tammie L.S. , Network, Dominantly Inherited Alzheimer, Goate, Alison M , Noble, James M

Mayo Clinic

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring | September 27, 2018 | Volume: 10 | Issue: 1 | Pages: 669-677

10.1016/j.dadm.2018.08.012 | PMID 30417072 Get It

AbstractIntroduction18F‐fluorodeoxyglucose (FDG) positron emission tomography (PET) is commonly used to estimate neuronal injury in Alzheimer's disease (AD). Here, we evaluate the utility of dynamic PET measures of perfusion using 11C‐Pittsburgh compound B (PiB) to estimate neuronal injury in comparison to FDG PET.MethodsFDG, early frames of PiB images, and relative PiB delivery rate constants (PiB‐R1) were obtained from 110 participants from the Dominantly Inherited Alzheimer Network. Voxelwise, regional cross‐sectional, and longitudinal analyses were done to evaluate the correlation between images and estimate the relationship of the imaging biomarkers with estimated time to disease progression based on family history.ResultsMetabolism and perfusion images were spatially correlated. Regional PiB‐R1 values and FDG, but not early frames of PiB images, significantly decreased in the mutation carriers with estimated year to onset and with increasing dementia severity.DiscussionHypometabolism estimated by PiB‐R1 may provide a measure of brain perfusion without increasing radiation exposure.
Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease
Preische, Oliver, Sohrabi, Hamid R. , Gräber, Susanne, Ringman, John M. , Martins, Ralph N. , Rossor, Martin N. , Fox, Nick N., Graff‐Radford, Neill R. , Xiong, Chengjie , Danek, Adrian , Vöglein, Jonathan , Salloway, Stephen , Xiong, Chengjie , Benzinger, Tammie L.S. , Buckles, Virginia, Masters, Colin L. , Bateman, Randall J. , Morris, John C. , Laske, Christoph , (DIAN), Dominantly Inherited Alzheimer Network, Fox, Nick C. , Bateman, Randall J , Masters, Colin L , Vöglein, Jonathan , Xiong, Chengjie , Benzinger, Tammie L S , Fox, Nick C , Morris, John C , Müller, Stephan, Jucker, Mathias , McDade, Eric , Schofield, Peter R. , Ghetti, Bernardino , Fox, Nick N., Sperling, Reisa Anne , (DIAN), Dominantly Inherited Alzheimer Network

Mayo Clinic

Alzheimer's & Dementia | September 25, 2018 | Volume: 14 | Issue: 11 | Pages: 1427-1437

10.1016/j.jalz.2018.06.3059 | PMID 30266303 Get It

AbstractIntroductionLittle is known about effects of physical activity (PA) in genetically driven early‐onset autosomal dominant Alzheimer's disease (AD).MethodsA total of 372 individuals participating at the Dominantly Inherited Alzheimer Network study were examined to evaluate the cross‐sectional relationship of PA with cognitive performance, functional status, cognitive decline, and AD biomarkers in cerebrospinal fluid. Mutation carriers were categorized as high or low exercisers according to WHO recommendations.ResultsMutation carriers with high PA showed significantly better cognitive and functional performance and significantly less AD‐like pathology in cerebrospinal fluid than individuals with low PA. Mutation carriers with high PA scored 3.4 points better on Mini Mental State Examination at expected symptom onset and fulfilled the diagnosis of very mild dementia 15.1 years later compared with low exercisers.DiscussionThese results support a beneficial effect of PA on cognition and AD pathology even in individuals with genetically driven autosomal dominant AD.