Citations

Showing 10 of 108015 citations.

The prognostic advantage of calreticulin mutations in myelofibrosis might be confined to type 1 or type 1-like CALR variants
Tefferi, Ayalew , Tischer, Alexander , Wassie, Emnet A, Finke, Christy M. , Belachew, Alem A. , Ketterling, Rhett P. , Hanson, Curtis A. , Pardanani, Animesh , Lasho, Terra L. , Pardanani, Animesh D, Ketterling, Rhett P , Tischer, Alexander

Mayo Clinic

Blood | October 9, 2014 | Volume: 124 | Issue: 15 | Pages: 2465-2466

10.1182/blood-2014-07-588426 | PMID 25301336 Get It

A Novel Application of Teleneurology: Robotic Telepresence in Supervision of Neurology Trainees
Kramer, Neha M. , Demaerschalk, Bart M.

Mayo Clinic

Telemedicine and e-Health | October 9, 2014 | Volume: 20 | Issue: 12 | Pages: 1087-1092

10.1089/tmj.2014.0043 | PMID 25299842 Get It

Background: Telemedicine is used for specialist consultation, patient evaluation, and remote monitoring. We propose that telemedicine has a valuable role in medical education through facilitating faculty supervision of trainees. Materials and Methods: We surveyed resident physician trainees and faculty at a single institution who provided service for acute neurologic consultations over 29 months. The survey compared experiences using the supervisory methods of telephone, robotic telepresence (RTP), and in-person interaction. Participants answered 10 questions addressing their experience relevant to faculty–trainee interaction quality and clinical supervision, achieved with the three supervisory methods under study. Results: Surveys were received from 20 of 36 trainees (56%) and 8 of 10 faculty members (80%). More than 90% of trainees and faculty strongly agreed that in-person communication was satisfactory for patient data review, problem synthesis, and refinement of the trainees' impressions, with RTP ranking a close second. Moreover, 38% of faculty and 70% of trainees reported the telephone method as unsatisfactory for reacquisition of patient history, data synthesis, and direct observation of trainees' clinical skills. RTP provided more than 90% of trainees with sufficient staff support and facilitated trainee autonomy. Conclusions: Overall, 85% of both trainees and faculty preferred in-person supervision most, with RTP ranked second and telephone being least favored. Although in-person faculty supervision of trainees' management of neurologic emergencies is always preferred, it is not always practical. This survey highlights the valuable role of RTP in graduate medical education and RTP as preferred over telephone as an adjunctive supervision tool in residency.
Lithotripter Outcomes in a Community Practice Setting: Comparison of an Electromagnetic and an Electrohydraulic Lithotripter
Bhojani, Naeem , Mandeville, Jessica A. , Hameed, Tariq , Soergel, Trevor M., McAteer, James A., Williams, James C. , Krambeck, Amy E. , Lingeman, James E.

Mayo Clinic

Journal of Urology | October 9, 2014 | Volume: 193 | Issue: 3 | Pages: 875-879

10.1016/j.juro.2014.09.117 | PMID 25305356 Get It

Renal risk and response in amyloidosis
Dispenzieri, Angela , Dispenzieri, Angela

Mayo Clinic

Blood | October 9, 2014 | Volume: 124 | Issue: 15 | Pages: 2315-2316

10.1182/blood-2014-08-596338 | PMID 25301329 Get It

Rheumatoid Arthritis is Associated With Higher Ninety‐Day Hospital Readmission Rates Compared to Osteoarthritis After Hip or Knee Arthroplasty: A Cohort Study
Singh, Jasvinder A. , Inacio, Maria C. , Namba, Robert S. , Paxton, Elizabeth W. , Singh, Jasvinder A

Mayo Clinic

Arthritis Care & Research | October 9, 2014 | Volume: 67 | Issue: 5 | Pages: 718-724

10.1002/acr.22497 | PMID 25302697 Get It

ObjectiveTo examine whether an underlying diagnosis of rheumatoid arthritis (RA) or osteoarthritis (OA) impacts the 90‐day readmission rates after total hip arthroplasty (THA) or total knee arthroplasty (TKA).MethodsWe analyzed prospectively collected data from an integrated health care system, Total Joint Replacement Registry, of adults with RA or OA undergoing unilateral primary THA or TKA during 2009–2011. Adjusted logistic regression models for 90‐day readmission were fit. Odds ratios with 95% confidence intervals (95% CIs) were calculated. Study year was an effect modifier for the outcome; therefore separate analyses were conducted for each of the 3 study years.ResultsOf the 34,311 patients, 496 had RA and 33,815 had OA. Comparisons of RA and OA patients, respectively, were 73% and 61% women, 45% and 70% white, and patients had a mean age of 61 versus 67 years (P < 0.001). Crude 90‐day readmission rates for RA and OA were 8.5% and 6.7%, respectively. The adjusted odds of 90‐day readmission increased from year to year for RA compared to OA patients, from 0.89 (95% CI 0.46–1.71) in 2009 to 1.34 (95% CI 0.69–2.61) in 2010, and to 1.74 (95% CI 1.16–2.60) in 2011. The 2 most common readmission reasons were joint prosthesis infection (10.2%) and septicemia (10.2%) in RA and joint prosthesis infection (5.7%) and other postoperative infection (5.1%) in OA.ConclusionRA is a risk factor for 90‐day readmission after primary THA or TKA. An increasing risk of readmissions noted in RA in 2011 is concerning and indicates that further studies should examine the reasons for this increasing trend.
Microvascular Free Flap for Total Eyelid Reconstruction With a Visually Useful Eye
Ghadiali, Larissa, Patel, Payal , Levine, Jamie P. , Gold, Katherine G., Lisman, Richard D. , Ghadiali, Larissa K

Mayo Clinic

Ophthalmic Plastic & Reconstructive Surgery | October 9, 2014 | Volume: 32 | Issue: 5 | Pages: e109-e111

10.1097/iop.0000000000000288 | PMID 25299739 Get It

Total eyelid loss, full thickness loss of the upper and lower eyelids, is uncommon and surgically challenging. Eyelid reconstruction after such injuries can be further complicated by loss of adjacent tissue. When tissue for local flaps is unavailable, free flaps must be considered. Few cases of total eyelid reconstruction via microvascular free flap have been reported, especially with an intact globe and good visual acuity. In this report, we describe the use of a microvascular free flap based on the radial artery for total eyelid reconstruction in a patient with an intact globe and useful visual acuity.
Pulmonary masses in a patient with dyspnea: Apply Occam's razor or Hickam's dictum?
Leung, Nelson , Grogan, Martha , Johnson, Geoffrey B. , Klecka, Mary E., Dispenzeiri, Angela, Johnson, Geoffrey B. , Leung, Nelson , Johnson, Geoffrey B , Johnson, Geoffrey B

Mayo Clinic

American Journal of Hematology | October 9, 2014 | Volume: 90 | Issue: 5 | Pages: 462-465

10.1002/ajh.23870 | PMID 25297538 Get It

Exclusive periductal/pericystic growth pattern in a case of long‐standing monophasic synovial sarcoma of the parotid gland
Manuguerra, Roberta , Bianchi, Bernardo , Ferri, Andrea , Filippo, Massimo De , Lanfranco, Davide, Sukov, William R. , Silini, Enrico Maria , Corradi, Domenico

Mayo Clinic

Histopathology | October 9, 2014 | Volume: 67 | Issue: 1 | Pages: 130-133

10.1111/his.12579 | PMID 25296532 Get It

Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges
Hoelzinger, Dominique B. , Cohen, Peter A. , Gendler, Sandra , Dominguez, Ana Lucía , Gendler, Sandra J

Mayo Clinic

Cancer Research | October 9, 2014 | Volume: 74 | Issue: 23 | Pages: 6845-6855

10.1158/0008-5472.can-14-0836 | PMID 25297635 Get It

Abstract The tolerogenic cytokine IL9 promotes T regulatory cell function and allergic airway inflammation, but it has not been extensively studied in cancer. In this report, we used IL9-deficient mice to investigate the effects of IL9 in multiple models of breast and colon cancer development. Eliminating endogenous IL9 enabled sensitization of host T cells to tumors, leading to their early rejection without the requirement of vaccines or immunomodulatory therapies. Notably, IL9-deficient mice acquired immunologic memory, which actively protected from residual disease and tumor rechallenge, an effect linked to activation of CD8+ T cells. Depletion of either CD8+ or CD4+ T cells abolished the benefits of IL9 loss to tumor control. Adoptive transfer experiments showed that T cells from tumor-rejecting IL9-deficient mice retained their effector competency in wild-type animals. Moreover, neutralizing IL9 antibody phenocopied the effects of IL9 gene deletion by slowing tumor progression in wild-type animals. Our results show the ability of IL9 to function as an inhibitor of adaptive immunity that prevents the formation of immunologic memory to a growing tumor, highlighting the potential for IL9 neutralization as a unique tool for cancer immunotherapy. Cancer Res; 74(23); 6845–55. ©2014 AACR.
Distal Femoral Subchondral Metastasis Mistaken for an Insufficiency Fracture and Treated with Total Knee Arthroplasty
Born, Trevor, Rose, Peter S. , Mabry, Tad M. , Born, Trevor R

Mayo Clinic

JBJS Case Connector | October 8, 2014 | Volume: 4 | Issue: 4 | Pages: e91

10.2106/jbjs.cc.m.00303 | PMID 29252759 Get It

Case: A seventy-three-year-old woman who had been given the tentative diagnosis of spontaneous osteonecrosis presented to our clinic for a second opinion. Additional imaging and evaluation revealed the lesion to be a subchondral metastasis consistent with breast cancer. She received proper oncologic treatment and subsequent total knee arthroplasty. Conclusion: Orthopaedic surgeons should be aware of the possibility of metastatic disease manifesting itself in the form of an isolated subchondral lesion about the knee. For patients with such lesions, treatment in the form of total knee arthroplasty is a viable option that can provide excellent pain relief and function.