Citations

Context: There is need for an up-to-date comprehensive review of baseball interval throwing programs in the literature. Objective: To (1) understand the origin and basis of interval throwing programs; (2) evaluate the content of programs in the peer-reviewed literature including target audience, initiation criteria, throwing specifics, arm care, and performance evaluation metrics; (3) classify these variables as well defined, ambiguous, or missing; and (4) analyze variability in key aspects including starting criteria, length, progression, and completion criteria. Data Sources: Medline, Embase, Cochrane Reviews, Web of Science, and Scopus Study Selection: The full text of studies, in English, had to be available. Included studies had to contain a complete interval throwing program designed for baseball players. Study Design: Systematic review. Level of Evidence: Level 4. Data Extraction: Initial screening was conducted based on article title and abstract. Full text of the remaining articles was evaluated for fulfillment of inclusion criteria. Results: Nine studies initially met inclusion criteria. The programs’ comprehensiveness was poor, with a mean Interval Throwing Program Checklist score of 20 (range 14-23) on a scale of 0 to 30. There were a variety of components, including progressive long toss, weighted ball, and throwing mechanics exercises. The programs identified had significant heterogeneity in duration, intensity, progression, and focus. Overall, there was a significant lack of attempts at validation or formal study of efficacy for published throwing programs. Conclusion: Current published interval throwing programs are mostly variations of an original program published many years ago and were based on principles of progressive loading with pain as sign of injury that should be monitored carefully. However, these programs have minimal clinical validation and objective measures to quantify their effectiveness. This work identifies several limitations in the current literature and can serve as a foundation for future development of evidence-based interval throwing programs.

Background: Collaborative methods are necessary to meet patient palliative care (PC) needs because of the inadequate supply of PC specialists. Objective: This study aimed to conduct a needs assessment and determine primary care, emergency, and hospital physicians’ general attitudes about primary PCs, confidence in managing common PC scenarios, and preferences for interaction with specialty PCs. Design: A sequential mixed-methods study design was used, whereby individual qualitative interviews informed the content of a quantitative survey. Semistructured telephone interviews were conducted by a member of the study team with expertise in qualitative research methods. Setting/Subjects: The quantitative survey, delivered to primary care, emergency, and hospital physicians across four distinct geographic locations of a large health system, solicited impressions on common clinical PC scenarios that might pose challenges. Measurements: Survey data included demographic information, clinician confidence levels, preferences for support in managing PC scenarios, and likelihood to refer to PC. Results: The quantitative survey was completed by 126 physicians (response rate, 13.9%). Overall mean (standard deviation) confidence levels were lowest for a scenario about handling pain (5.57 [2.35] out of 10) and highest for goals-of-care conversations with the patient (7.80 [2.02]). Spearman correlations between mean confidence and likelihood to refer to PC demonstrated weak to moderate inverse correlations. Respondents with previous training in PC had higher mean confidence in managing symptoms and goals-of-care conversations. Conclusions: Continuing efforts are needed to help improve physicians’ confidence in primary PC skills and develop innovative methods to provide collaborative support of specialty PCs across various specialties and PC needs.

Purpose To describe the clinical characteristics, histopathologic subtype distribution, treatment, and outcomes of patients with primary orbital lymphoma. Major Findings There were 126 biopsy-confirmed cases of primary orbital lymphoma, with 81 (64.3%) female and 110 (87.3%) white. The average age at diagnosis was 62.7 ± 13.9 years. There were 26 (20.6%) cases with bilateral involvement. The most frequent lymphoma subtype was MALT lymphoma (N = 76, 60.3%), followed by diffuse large B-cell lymphoma (N = 18, 14.3%) and follicular lymphoma (N = 12, 9.5%). Prognosis was generally favorable, as local recurrence occurred in only 14 (11.1%) patients and final best corrected visual acuity (BCVA) loss of >1 line was seen in 30 (28.0%) patients. Bilateral lymphoma and advanced stage (Ann Arbor Stage III or IV) at presentation were associated with increased risk of local recurrence ( p = 0.0025, p = 0.049). Improved disease-specific survival was associated with diagnosis at Stage I or II ( p = 0.013), MALT subtype ( p = 0.034), or lack of chemotherapy requirement as primary treatment ( p = 0.0073). Conclusions In this single center academic cohort, MALT lymphoma subtype was most common. Overall orbital recurrence frequency was low, and bilateral lymphoma and advanced stage were associated with increased risk of local recurrence. MALT lymphoma subtype was associated with improved disease-specific survival. Long-term follow-up showed that most patients retained good visual acuity in the affected eye(s).

Objective: There is little existing literature describing the evaluation and treatment of patients referred to surgical subspecialities for recurrent urinary tract infections (rUTIs). We hypothesised female patients referred to urology and urogynaecology for rUTI undergo multiple diagnostic tests and few would undergo surgery. Materials and Methods: This is a retrospective review of female patients referred to urology or urogynaecology at a single institution between 2016 and 2019. Data on demographics, provider speciality, diagnostic tests performed, and surgeries were abstracted. Descriptive statistics were used and a logistic regression was performed to determine the adjusted odds ratio of undergoing a surgery. Results: A total of 990 patients were included with a mean age of 62 and on average underwent 3.7 different testing modalities, including genitourinary (GU) examination (62.3%), urodynamic testing (72.7%), cystoscopy (66.0%), and imaging (70.7%). Urologists more commonly pursued urodynamic testing, cystoscopy, and imaging than urogynaecologists. Ultimately, 21.4% of all patients underwent a surgical procedure. Patients who were seen by urogynaecology, underwent GU examination, urodynamic testing, or cystoscopy had higher likelihoods of eventually undergoing surgery (procedure under anaesthesia). Conclusion: Female rUTI patients referred to urology or urogynaecology undergo considerable evaluation and testing. The majority of patients are ultimately managed medically rather than surgically, indicating continued need for resource stewardship. Level of evidence: Not applicable.

Abstract Introduction Acoustic analysis of speech has discriminated decompensated acute heart failure (HF). Speech rate (SR) and cepstral peak prominence (CPP) variation are among features previously evaluated. However, the association between SR and CPP and chronic stable HF with and without pulmonary hypertension (PH) as well as PH alone have not been previously studied. Methods Patients evaluated for HF and/or PH in the outpatient setting recorded a standardized text read out loud from which a sentence was extracted and analysed to extract pre-specified acoustic features including SR and CPP calculated for voiced speech (CPP-V) and in all speech (CPP-All). Patients were grouped depending on the presence or absence of disease (HF and/or PH) and symptoms. Linear regression models were fitted to determine the association between each acoustic feature and disease status. Results In total, 2153 patients were included: age 65.32 ± 17.18 years; male n = 1246 (57.9%); 879 had HF (40.8%), 542 had PH (25.2%) and 777 had no disease and no symptoms (36.1%). After adjustment for age and sex, SR was significantly lower in patients with PH only [estimated coefficient, 95% confidence interval (CI): −0.14, −0.21 to −0.06, P = 0.0006], HF only (−0.11, −0.17 to −0.05, P = 0.0002) and HF with PH (−0.17, −0.24 to −0.10, P < 0.0001) compared with no disease. CPP-V differed in patients with PH only (0.37, 0.16–0.57, P = 0.0004) and CPP-All differed significantly compared with patients without disease (0.23, 0.08–0.38, P = 0.0025). Conclusions SR is significantly slower in patients with HF alone, PH alone and HF and PH combined compared with patients without disease. CPP also differs significantly in patients with PH compared with controls. These findings suggest that acoustic analysis may be useful in discriminating chronic stable HF and PH, offering promise for the development of non-invasive screening methods for HF and PH.