Citations

Showing 10 of 107868 citations.

P‐127: Apathy is a better predictor of mild cognitive impairment than depression: A population based study
Rocca, Walter A. , Pankratz, Shane, Roberts, Rosebud O., Petersen, Ronald C. , Geda, Yonas E. , Knopman, David S.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_2 | Pages: No page available

10.1016/j.jalz.2007.04.191 Get It

O1–04–08: PIB and MRI provide complementary information in imaging of AD and MCI
Lowe, Val J. , Kemp, Bradley J. , Shiung, Maria, Weigand, Stephen D. , Petersen, Ronald C. , Jack, Clifford R. , Knopman, David S. , Boeve, Bradley F.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.084 Get It

O1–04–04: The Alzheimer's disease neuroimaging initiative: Progress report
Weiner, Michael W. , Thal, Leon J., Petersen, Ronald C. , Jagust, William J. , Trojanowski, John Q., Shaw, Leslie M. , Gamst, Anthony, Jack, Clifford R. , Trojanowski, John Q., Toga, Arthur W. , Beckett, Laurel

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.080 Get It

O1–04–01: Quantitative evaluation of PIB PET and FDG PET in early cognitive impairment
Lowe, Val J. , Kemp, Brad , Petersen, Ronald C. , Jack, Clifford R. , Mathis, Chester A. , Klunk, William E.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.077 Get It

O1–05–03: PET measurements of posterior cingulate glucose metabolism are superior to MRI measurements of hippocampal volume in distinguishing cognitively normal persons at differential genetic risk for Alzheimer's disease
Reiman, Eric M. , Alexander, Gene E. , Reschke, Cole, Lee, Wendy , Smilovici, Oded, Buckley, Shannon, Sacrey, Diana Truran, Schuff, Norbert, Müller, Stig , Weiner, Michael W. , Caselli, Richard J., Chen, Kewei , Smilovici, Oded

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.070 Get It

S2–01–01: Role of vascular risk factors in cognitive decline beginning in middle age
Coker, Laura H., Knopman, David S. , Catellier, Diane , Mosley, Thomas H.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.059 Get It

O2–02–07: Hippocampal diffusivity on DTI differ between amnestic and non‐amnestic MCI
Avula, Ramesh, Przybelski, Scott A. , Weigand, Stephen D. , Petersen, Ronald C. , Kantarci, Kejal , Boeve, Bradley F. , Knopman, David S. , Smith, Glenn E. , Vemuri, Prashanthi , Jack, Clifford R.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.041 Get It

O2–02–01: Patterns of atrophy on voxel based morphometry differ between amnestic MCI converters and nonconverters
Whitwell, Jennifer L. , Weigand, Stephen D. , Przybelski, Scott A. , Petersen, Ronald C. , Boeve, Bradley F. , Knopman, David S. , Jack, Clifford R.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.035 Get It

O2–03–03: Selective T1‐weighted enhancement of individual Alzheimer's disease amyloid plaques using an antibody fragment against Aβ42 as a magnetic resonance molecular imaging contrast agent
Poduslo, Joseph F., Ramakrishnan, Muthu, Wengenack, Thomas M., Curran, Geoffry L., Gilles, Emily J., Kandimalla, Karunya K. , Ramı́rez-Alvarado, Marina , Garwood, Michael , Jack, Clifford R.

Mayo Clinic

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.028 Get It

Platelet-Derived Growth Factor Receptor β–Mediated Phosphorylation of MUC1 Enhances Invasiveness in Pancreatic Adenocarcinoma Cells
Singh, Pankaj K. , Wen, Yunfei, Swanson, Benjamin J., Shanmugam, Kandavel , Kazlauskas, Andrius , Cerny, Ronald L. , Gendler, Sandra , Hollingsworth, Michael A.

Mayo Clinic

Cancer Research | June 1, 2007 | Volume: 67 | Issue: 11 | Pages: 5201-5210

10.1158/0008-5472.can-06-4647 | PMID 17545600 Get It

Abstract MUC1 is a heterodimeric transmembrane glycoprotein that is overexpressed and aberrantly glycosylated in ductal adenocarcinomas. Differential phosphorylation of the MUC1 cytoplasmic tail (MUC1CT) has been associated with signaling events that influence the proliferation and metastasis of cancer cells. We identified a novel tyrosine phosphorylation site (HGRYVPP) in the MUC1CT by mass spectrometric analysis of MUC1 from human pancreatic adenocarcinoma cell lines. Analyses in vitro and in vivo showed that platelet-derived growth factor receptor β (PDGFRβ) catalyzed phosphorylation of this site and of tyrosine in the RDTYHPM site. Stimulation of S2-013.MUC1F cells with PDGF-BB increased nuclear colocalization of MUC1CT and β-catenin. PDGF-BB stimulation had no significant effect on cell proliferation rate; however, it enhanced invasion in vitro through Matrigel and in vivo tumor growth and metastases. Invasive properties of the cells were significantly altered on expression of phosphorylation-abrogating or phosphorylation-mimicking mutations at these sites. We propose that interactions of MUC1 and PDGFRβ induce signal transduction events that influence the metastatic properties of pancreatic adenocarcinoma. [Cancer Res 2007;67(11):5201–10]