Citations

Mayo Clinic

Clear

66 citation(s) found for "Pagnano, Mark W".

Tibiofemoral Alignment for Total Knee Arthroplasty: Differences Between Static and Dynamic Tibial Plateau Loading
Miller, Emily J. , Pagnano, Mark W. , Kaufman, Kenton R. , Kaufman, Kenton R

ASME 2010 Summer Bioengineering Conference, Parts A and B | July 15, 2013 | Volume: No volume available | Issue: No issue available | Pages: 409-410

10.1115/sbc2010-19139 Get It

The surgical goal in total knee arthroplasty (TKA) is to obtain neutral mechanical alignment within three degrees [4]. This has been considered necessary to achieve optimal function, produce balanced medial and lateral loading distributions, and prolong implant longevity [7]. Under static loading, tibial-femoral alignment angle deviations of 3° have been shown to greatly alter the distribution of pressure and load between the medial and lateral tibial plateaus [13]. However, other studies have challenged the practice that coronal tibiofemoral alignment improves implant longevity [9,10]. These studies did not show a statistical difference in the number of revision surgeries between well aligned knees and mechanical alignment outliers (varus/valgus knees). While it has been suggested that accurate alignment allows for improved joint kinematics and improved outcomes in TKA patients [6], no studies have evaluated the effect of tibial-femoral alignment on tibial plateau loading distribution during gait in the TKA population. Therefore, the purpose of this study was to assess tibial plateau loading following TKA.
Minimising blood loss and transfusion in contemporary hip and knee arthroplasty
Watts, Chad D. , Pagnano, Mark W. , Pagnano, Mark W

The Journal of Bone and Joint Surgery. British volume | November 1, 2012 | Volume: 94-B | Issue: 11_Supple_A | Pages: 8-10

10.1302/0301-620x.94b11.30618 | PMID 23118371 Get It

Despite advances in contemporary hip and knee arthroplasty, blood loss continues to be an issue. Though blood transfusion has long been used to treat post-operative anemia, the associated risks are well established. The objective of this article is to present two practical and effective approaches to minimising blood loss and transfusion rates in hip and knee arthroplasty: the use of antifibrinolytic medications such as tranexamic acid and the adoption of more conservative transfusion indications.
Ulnar Collateral Ligament Reconstruction With Gracilis Tendon in Athletes With Intraligamentous Bony Excision
Dugas, Jeffrey R., Bilotta, Jessica, Watts, Chad D. , Crum, Joshua A., McMichael, Christopher S., Cain, E. Lyle , Andrews, James R., Fleisig, Glenn S. , Pagnano, Mark W

The American Journal of Sports Medicine | May 11, 2012 | Volume: 40 | Issue: 7 | Pages: 1578-1582

10.1177/0363546512446927 | PMID 22582225 Get It

Background: Ulnar collateral ligament (UCL) reconstruction is frequently performed in throwing athletes, but outcomes of UCL reconstruction requiring excision of bone, either within the substance of or replacing the UCL, have not been studied. Hypothesis: Clinical outcome for throwing athletes after UCL reconstruction with gracilis tendon will be less favorable for patients requiring concurrent excision of bone from within the substance of the UCL than for patients with no bone excision within, or replacing, the ligamentous anatomy. Study Design: Cohort Study; Level of evidence, 3. Methods: One hundred twenty pitchers of competitive levels between high school and major league who underwent UCL reconstruction using contralateral gracilis autografts completed a phone survey, and their medical charts were reviewed. Follow-up was a minimum of 2 years. Among the 120 patients, 42 (35%) had bone within, or replacing, the substance of the native UCL (bony group), and 78 (65%) had no bony abnormalities (nonbony group). The latter group of 78 underwent UCL reconstruction using gracilis tendon graft due to the absence of a palmaris longus tendon. Clinical outcomes were compared between the 2 study groups using t tests and χ 2 analyses. Results: There were no statistical differences regarding time to return to throwing, time to return to competition, postoperative complications, or need for additional surgeries. The percentage of patients who returned to the same or higher level was higher in the nonbony group (91%) than in the bony group (81%), but this trend was not statistically significant ( P = .083), likely due to a relatively small sample size. Changes in self-reported pitch control were different ( P = .029) between the 2 groups, with a greater percentage of pitchers experiencing decreased control in the bony group. Conclusion: The presence of bone concomitant with UCL damage can lead to pitch control problems after UCL reconstruction and may also decrease the chance of return to play.
Perioperative Nerve Injury after Total Hip Arthroplasty
Jacob, Adam K. , Mantilla, Carlos B. , Sviggum, Hans P. , Schroeder, Darrell R. , Pagnano, Mark W. , Hebl, James R., Mantilla, Carlos B , Schroeder, Darrell

Anesthesiology | October 4, 2011 | Volume: 115 | Issue: 6 | Pages: 1172-1178

10.1097/aln.0b013e3182326c20 | PMID 21934486 Get It

Background Perioperative nerve injury (PNI) is a recognized complication of total hip arthroplasty (THA). Regional anesthesia (RA) techniques may increase the risk of neurologic injury. Using a retrospective cohort study, the authors tested the hypothesis that use of RA increases the risk for PNI after elective THA. Methods All adult patients who underwent elective THA at Mayo Clinic during a 20-yr period were included. The primary outcome was the presence of a new PNI within 3 months of surgery. Multivariable logistic regression was used to evaluate patient, surgical, and anesthetic risk factors for PNI. Results Of 12,998 patients undergoing THA, 93 experienced PNI (incidence = 0.72%; 95% CI 0.58-0.88%). PNI was not associated with type of anesthesia (OR = 0.72 for neuraxial-combined vs. general; 95% CI 0.46-1.14) or peripheral nerve blockade (OR = 0.65; 95% CI 0.34-1.21). The risk for PNI was associated with younger age (OR = 0.79 per 10-yr increase; 95% CI 0.69-0.90), female gender (OR = 1.72; 95% CI 1.12-2.64), longer operations (OR = 1.10 per 30-min increase; 95% CI 1.03-1.18) or posterior surgical approach (OR = 1.91 vs. anterior approach; 95% CI 1.22-2.99). Neurologic recovery was not influenced by the use of RA techniques in patients with PNI. Conclusions The risk for PNI after THA was not increased with the use of neuraxial anesthesia or peripheral nerve blockade. Neurologic recovery in patients who experienced PNI was not affected by the use of RA. These results support the use of RA techniques in patients undergoing elective THA given their known functional and clinical benefits.
Perioperative Nerve Injury after Total Knee Arthroplasty
Jacob, Adam K. , Mantilla, Carlos B. , Sviggum, Hans P. , Schroeder, Darrell R. , Pagnano, Mark W. , Hebl, James R., Mantilla, Carlos B , Schroeder, Darrell

Anesthesiology | January 15, 2011 | Volume: 114 | Issue: 2 | Pages: 311-317

10.1097/aln.0b013e3182039f5d | PMID 21239974 Get It

Background Perioperative nerve injury (PNI) is one of the most debilitating complications after total knee arthroplasty (TKA). Although regional anesthesia (RA) techniques reduce pain and improve functional outcomes after TKA, they may also contribute to PNI. The objective of this study was to test the hypothesis that PNI risk differs among patients according to RA use during TKA. Methods All patients aged at least 18 yr who underwent elective TKA from January 1988 to July 2007 were retrospectively identified. The primary outcome variable was the presence of a new PNI documented within 3 months of the procedural date. Age, sex, body mass index, type of procedure, tourniquet time, type of anesthesia, and use of peripheral nerve blockade were evaluated as potential risk factors for PNI using multivariable logistic regression. Results Ninety-seven cases of PNI were identified among 12,329 patients. Overall incidence of PNI was 0.79% (95% CI, 0.64-0.96%). PNI was not associated with peripheral nerve blockade (odds ratio [OR], 0.97) or type of anesthesia (OR, 1.10 [neuraxial vs. general]; OR, 1.82 [combined vs. general]). Risk for PNI decreased with age (OR, 0.68 [per decade]; P < 0.001) but increased with tourniquet time (OR, 1.28 [per 30-min increase]; P = 0.003) and bilateral procedures (OR, 2.51; P < 0.001). Patients with PNI who underwent peripheral nerve blockade were less likely to have complete neurologic recovery (OR, 0.37; P = 0.03). Conclusions Risk for PNI after TKA was unchanged by the use of RA techniques. This finding supports the notion that the known benefits of RA for patients undergoing TKA can be achieved without increasing risk of neurologic injury. However, in rare situations when PNI occurs, complete recovery may be less likely if it develops after peripheral nerve blockade.
Difficulties with the “N + 7 Rule” in endoscopic anterior cruciate ligament reconstruction
Pagnano, Mark W., Kim, Chang-Woo , Huie, Gordon, Pagnano, Mark W. , Scott, W. Norman

Arthroscopy | June 2, 2004 | Volume: 13 | Issue: 5 | Pages: 597-599

10.1016/s0749-8063(97)90186-9 | PMID 9343648 Get It

Abstract In an effort to facilitate the use of interference screw fixation in the tibia, a method to orient the tibial tunnel termed the “N + 7 Rule” was prospectively applied to 60 consecutive endoscopic anterior cruciate ligament reconstructions performed by a single surgeon. Four cases were excluded because a breach in the described protocol for application of the N + 7 rule was identified at the time of the operation. Of the remaining 56 cases, 28 (50%) were fixed with an interference screw on the tibia, whereas 28 (50%) required fixation with sutures tied over a post. The 28 cases not amenable to interference screw fixation included 17 cases in which the tibial tunel was too long and 11 cases in which the tunnnel was too short. It appears that the applicability of the N + 7 rule to an individual surgeon's practice may be altered by small variations in operative technique.