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66 citation(s) found for "Pagnano, Mark".

Review Article: The Rationale for Posterior Cruciate Substituting Total Knee Arthroplasty
Scuderi, Giles R. , Pagnano, Mark W.

Journal of Orthopaedic Surgery | October 4, 2016 | Volume: 9 | Issue: 2 | Pages: 81-88

10.1177/230949900100900217 | PMID 12118138 Get It

Greater inadvertent muscle damage in direct anterior approach when compared with the direct superior approach for total hip arthroplasty
Amanatullah, Derek F. , Masini, Michael A. , Roger, Douglas J. , Pagnano, Mark W.

The Bone & Joint Journal | August 1, 2016 | Volume: 98-B | Issue: 8 | Pages: 1036-1042

10.1302/0301-620x.98b8.37178 | PMID 27482014 Get It

AimsWe wished to quantify the extent of soft-tissue damage sustained during minimally invasive total hip arthroplasty through the direct anterior (DA) and direct superior (DS) approaches.Materials and MethodsIn eight cadavers, the DA approach was performed on one side, and the DS approach on the other, a single brand of uncemented hip prosthesis was implanted by two surgeons, considered expert in their surgical approaches. Subsequent reflection of the gluteus maximus allowed the extent of muscle and tendon damage to be measured and the percentage damage to each anatomical structure to be calculated.ResultsThe DA approach caused substantially greater damage to the gluteus minimus muscle and tendon when compared with the DS approach (t-test, p = 0.049 and 0.003, respectively). The tensor fascia lata and rectus femoris muscles were damaged only in the DA approach. There was no difference in the amount of damage to the gluteus medius muscle and tendon, piriformis tendon, obturator internus tendon, obturator externus tendon or quadratus femoris muscle between approaches. The posterior soft-tissue releases of the DA approach damaged the gluteus minimus muscle and tendon, piriformis tendon and obturator internus tendon.ConclusionThe DS approach caused less soft-tissue damage than the DA approach. However the clinical relevance is unknown. Further clinical outcome studies, radiographic evaluation of component position, gait analyses and serum biomarker levels are necessary to evaluate and corroborate the safety and efficacy of the DS approach. Cite this article: Bone Joint J 2016;98-B1036–42.
Functional and oncologic outcome of cemented endoprosthesis for malignant proximal femoral tumors
Watts, Chad D. , Rose, Peter S. , Taunton, Michael J. , Sim, Franklin H. , Wyles, Cody C. , Houdek, Matthew T. , Taunton, Michael J , Pagnano, Mark W

Journal of Surgical Oncology | June 29, 2016 | Volume: 114 | Issue: 4 | Pages: 501-506

10.1002/jso.24339 | PMID 27353406 Get It

Epidemiology of periprosthetic femoral fractures in 5417 revision total hip arthroplasties
Watts, Chad D. , Lewallen, David G. , Berry, Daniel J. , Abdel, Matthew P. , Houdek, Matthew T. , Berry, Daniel J , Pagnano, Mark W

The Bone & Joint Journal | April 1, 2016 | Volume: 98-B | Issue: 4 | Pages: 468-474

10.1302/0301-620x.98b4.37203 | PMID 27037428 Get It

Aims The goals of this study were to define the risk factors, characteristics, and chronology of fractures in 5417 revision total hip arthroplasties (THAs). Patients and Methods From our hospital’s prospectively collected database we identified all patients who had undergone a revision THA between 1969 and 2011 which involved the femoral stem. The patients’ medical records and radiographs were examined and the relevant data extracted. Post-operative periprosthetic fractures were classified using the Vancouver system. A total of 5417 revision THAs were identified. Results There were 668 intra-operative fractures, giving an incidence of 12%. Fractures were three times more common with uncemented stems (19%) than with cemented stems (6%) (p < 0.001). The incidence of intra-operative femoral fracture varied by uncemented stem type: fully-coated (20%); proximally-coated (19%); modular fluted tapered (16%) (p < 0.05). Most fractures occurred during the insertion of the femoral component (35%). One-third involved the diaphysis and 26% were of the calcar: 69% were undisplaced. There were 281 post-operative fractures of the femur (20-year probability = 11%). There was no difference in risk for cemented and uncemented stems. Post-operative fractures were more common in men < 70 years (p = 0.02). Periprosthetic fractures occurred earlier after uncemented revision of the femoral component, but later after a cemented revision. The most common fracture type was a Vancouver B 1 (31%). Of all post-operative fractures, 24% underwent open reduction and internal fixation and 15% revision arthroplasty. Conclusion In revision THA, intra-operative fractures occurred three times more often with an uncemented stem. Many were undisplaced diaphyseal fractures treated with cerclage fixation. While the risk of post-operative fracture is similar between uncemented and cemented components, they occur at notably different times depending on the type of stem fixation. Take home message: In revision THA, intra-operative periprosthetic femoral fractures occur three times more often with uncemented stems. Many are non-displaced diaphyseal fractures treated with cerclage fixation. While postoperative fracture risks are equivalent between uncemented and cemented components, they occur at notably different time periods based on stem fixation type. Cite this article: Bone Joint J 2016;98-B:468–74.
Epidemiology of periprosthetic fracture of the femur in 32 644 primary total hip arthroplasties
Watts, Chad D. , Lewallen, David G. , Abdel, Matthew P. , Houdek, Matthew T. , Berry, Daniel J. , Pagnano, Mark W

The Bone & Joint Journal | April 1, 2016 | Volume: 98-B | Issue: 4 | Pages: 461-467

10.1302/0301-620x.98b4.37201 | PMID 27037427 Get It

Aim and Methods The goals of this study were to define the risk factors, nature, chronology, and treatment strategies adopted for periprosthetic femoral fractures in 32 644 primary total hip arthroplasties (THAs). Results There were 564 intra-operative fractures (1.7%); 529 during uncemented stem placement (3.0%) and 35 during cemented stem placement (0.23%). Intra-operative fractures were more common in females and patients over 65 years (p < 0.001). The majority occurred during placement of the femoral component (60%), and involved the calcar (69%). There were 557 post-operative fractures (20-year probability: 3.5%; 95% confidence interval (CI) 3.2 to 3.9); 335 fractures after placement of an uncemented stem (20-year probability: 7.7%; 95% CI 6.2 to 9.1) and 222 after placement of a cemented stem (20-year probability: 2.1%; 95% CI 1.8 to 2.5). The probability of a post-operative fracture within 30 days after an uncemented stem was ten times higher than a cemented stem. The most common post-operative fracture type was a Vancouver A G (32%; n = 135), with 67% occurring after a fall. In all, 36% (n = 152) were treated with revision arthroplasty. Conclusion In summary, intra-operative fractures occur 14 times more often with uncemented stems. Female patients over 65 years of age are at highest risk. Post-operative fractures are also most common with uncemented stems, but are independent of age or gender. Cumulative risk of post-operative periprosthetic femur fracture was 3.5% at 20 years. Take home message: Intra-operative fractures occur 14 times more often with uncemented stems, particularly with female patients over 65 years of age, while post-operative fracture risk is independent of age or gender, but still increased with uncemented stems. Cite this article: Bone Joint J 2016;98-B:461–7.
Neutral mechanical alignment
Allen, Melissa M. , Pagnano, Mark W.

The Bone & Joint Journal | January 5, 2016 | Volume: 98-B | Issue: 1_Supple_A | Pages: 81-83

10.1302/0301-620x.98b1.36403 | PMID 26733648 Get It

The cause of dissatisfaction following total knee arthroplasty (TKA) remains elusive. Much attention has been focused on static mechanical alignment as a basis for surgical success and optimising outcomes. More recently, research on both normal and osteoarthritic knees, as well as kinematically aligned TKAs, has suggested that other specific and dynamic factors may be more important than a generic target of 0 ± 3º of a neutral axis. Consideration of these other variables is necessary to understand ideal targets and move beyond generic results. Cite this article: Bone Joint J 2016;98-B(1 Suppl A):81–3.
Bariatric surgery does not improve outcomes in patients undergoing primary total knee arthroplasty
Martin, J. Ryan , Watts, Chad D. , Taunton, Michael J. , Taunton, Michael J , Pagnano, Mark W

The Bone & Joint Journal | November 3, 2015 | Volume: 97-B | Issue: 11 | Pages: 1501-1505

10.1302/0301-620x.97b11.36477 | PMID 26530652 Get It

Bariatric surgery has been advocated as a means of reducing body mass index (BMI) and the risks associated with total knee arthroplasty (TKA). However, this has not been proved clinically. In order to determine the impact of bariatric surgery on the outcome of TKA, we identified a cohort of 91 TKAs that were performed in patients who had undergone bariatric surgery (bariatric cohort). These were matched with two separate cohorts of patients who had not undergone bariatric surgery. One was matched 1:1 with those with a higher pre-bariatric BMI (high BMI group), and the other was matched 1:2 based on those with a lower pre-TKA BMI (low BMI group). In the bariatric group, the mean BMI before bariatric surgery was 51.1 kg/m2 (37 to 72), which improved to 37.3 kg/m2 (24 to 59) at the time of TKA. Patients in the bariatric group had a higher risk of, and worse survival free of, re-operation (hazard ratio (HR) 2.6; 95% confidence interval (CI) 1.2 to 6.2; p = 0.02) compared with the high BMI group. Furthermore, the bariatric group had a higher risk of, and worse survival free of re-operation (HR 2.4; 95% CI 1.2 to 3.3; p = 0.2) and revision (HR 2.2; 95% CI 1.1 to 6.5; p = 0.04) compared with the low BMI group. While bariatric surgery reduced the BMI in our patients, more analysis is needed before recommending bariatric surgery before TKA in obese patients. Cite this article: Bone Joint J 2015;97-B:1501–5.
Open reduction and percutaneous fixation of a rare hamstring avulsion fracture
Watts, Chad D. , Cross, William W., Hartzler, Robert U. , Pagnano, Mark W

BMJ Case Reports | September 25, 2014 | Volume: 2014 | Issue: No issue available | Pages: bcr2014205256

10.1136/bcr-2014-205256 | PMID 25257887 Get It

Surgical treatment has been advocated for ischial tuberosity avulsion fractures in athletes. This article presents the case of an elite rower with a large avulsion fracture involving the entire inferior obturator ring with a novel technique for open reduction using a limited Kocher-Langenbeck approach and percutaneous fixation using posterior column lag screws. The fracture healed anatomically, and at 1 year follow-up the patient had full range of motion, normal gait and had returned to high-level sporting activities.
Tibiofemoral alignment in posterior stabilized total knee arthroplasty: Static alignment does not predict dynamic tibial plateau loading
Miller, Emily J. , Pagnano, Mark W. , Kaufman, Kenton R. , Kaufman, Kenton R

Journal of Orthopaedic Research | May 12, 2014 | Volume: 32 | Issue: 8 | Pages: 1068-1074

10.1002/jor.22644 | PMID 24820681 Get It

ABSTRACTFor total knee arthroplasty (TKA), neutral mechanical alignment produces balanced static knee loading. Dynamically, knee loading is affected by more than limb static alignment. We compared static and dynamic knee loading following TKA. Fifteen TKA patients were evaluated pre‐operatively and 2 months and 2 years post‐operatively. Tibiofemoral angles and medial tibial plateau loading were calculated. Pre‐operatively, static medial load was greater for varus than valgus knees. Post‐operatively, no relationship existed between tibiofemoral angle and static medial plateau load. Pre‐operatively and post‐operatively, dynamic medial load was not dependent on tibiofemoral angle. While all patients achieved equal static plateau load distributions at 2 years, only 47% had dynamic medial load distributions of 50 ± 10%. Static tibiofemoral alignment alone does not predict dynamic tibial loading. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 32:???–???, 2014.
Blood Management for Patients Undergoing Total Joint Arthroplasty
Pagnano, Mark W. , Kamath, Atul F, Kamath, Atul F.

JBJS Reviews | March 7, 2014 | Volume: 1 | Issue: 2 | Pages: No page available

10.2106/jbjs.rvw.m.00046 | PMID 27490505 Get It