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727 citation(s) found for "Xu, Jeff L".

Stereoscopic Particle Shadow Velocimetry
Harris, Jeff , McPhail, Michael, Truong, Christine , Fontaine, Arnold A., Harris, Jeff R.

Volume 7: Fluids Engineering | January 15, 2019 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1115/imece2018-88013 Get It

Stereoscopic particle image velocimetry (SPIV) is a variant of particle image velocimetry (PIV) that allows for the measurement of three components of velocity along a plane in a flow field. In PIV, particles in the flow field are tracked by reflecting laser light from tracer particles into two angled cameras, allowing for the velocity field to be determined. Particle shadow velocimetry (PSV) is an inherently less expensive velocity measurement method since the method images shadows cast by particles from an LED backlight instead of scattered light from a laser. Previous studies have shown that PSV is an adequate substitute for PIV for many two-dimensional, two-component velocimetry measurements. In this work, the viability of the two-dimensional, three-component stereoscopic particle shadow velocimetry (SPSV) is demonstrated by using SPSV to examine a simple jet flow. Results obtained using SPIV are also used to provide benchmark comparison for SPSV measurements. Results show that in-plane and out-of-plane velocities measured using SPSV are comparable to those measured using SPIV.
Multicenter Interrater Reliability in the Endoscopic Assessment of Velopharyngeal Function Using a Video Instruction Tool
Miller, C. L., Bly, Randall A. , Cofer, Shelagh A. , Dahl, John P. , Serres, Lianne M. de, Goudy, Steven L. , Hartzell, Larry D. , Jabbour, Noel , Kacmarysnki, Deborah, MacArthur, Carol J. , Messner, Anna H. , Milczuk, Henry A., Rastatter, Jeff C., Rosenthal, Laura H. Swibel , Scott, Andrew R. , Woolley, Audie L., Zdanski, Carlton J. , Zopf, Dave A., Sie, Kathleen C.Y. , Cofer, Shelagh, Miller, Craig, Tollefson, Travis T.

Otolaryngology–Head and Neck Surgery | January 15, 2019 | Volume: 160 | Issue: 4 | Pages: 720-728

10.1177/0194599818822989 | PMID 30642231 Get It

ObjectiveAssess interrater agreement of endoscopic assessment of velopharyngeal (VP) function before and after viewing the video instruction tool (VIT). We hypothesized improvement in interrater agreement using the Golding‐Kushner scale (GKS) after viewing the VIT.Study DesignProspective study.SettingMulti‐institutional.MethodsSixteen fellowship‐trained pediatric otolaryngologists who treat velopharyngeal insufficiency (VPI) rated 50 video segments using the GKS before and after watching the VIT. Raters assessed gap size percentage and lateral pharyngeal wall (LPW), soft palate (SP), and posterior pharyngeal wall (PPW) movement. Intraclass correlation coefficient was estimated for these continuous measures. Raters also indicated the presence of a palatal notch, Passavant's ridge, and aberrant pulsations (categorical variables). Fleiss κ coefficient was used for categorical variables. Wilcoxon signed‐rank test was performed on the difference between the pre/post individual video ratings.ResultsReliability improved for all continuous variables after watching the instructional video. The improvement was significant for PPW (0.22‐0.30, P <. 001), SP (left: 0.63‐0.68, P <. 001 and right: 0.64‐0.68, P =. 001), and LPW (left: 0.49‐0.54, P =. 01 and right: 0.49‐0.54, P =. 09) but not significant for gap size (0.65‐0.69, P =. 36). Among categorical variables, agreement on Passavant's ridge significantly improved (0.30‐0.36, P =. 03).ConclusionExposure to a video instruction tool improves interrater agreement of endoscopic assessment of VP function. Significant improvement was observed in our primary end points, specifically posterior pharyngeal wall movement, soft palate movement, and lateral pharyngeal wall movement. There was less impact of the VIT on the interrater agreement of the categorical variables, palatal notch, Passavant's ridge, and aberrant pulsations.
Impact of vaginal dehydroepiandosterone (DHEA) on vaginal symptoms in female cancer survivors: Trial N10C1 (Alliance).
Barton, Debra L. , Sloan, Jeff A. , Shuster, Lynne T., Gill, Paula, Bearden, James D. , Johnson, David , Stella, Philip J., Terstriep, Shelby A., Rana, Fauzia , Anderson, D. Mark , Loprinzi, Charles L. , Anderson, Daniel M.

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 9507-9507

10.1200/jco.2014.32.15_suppl.9507 Get It

ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response.
McNeish, Iain A. , Allen, Andrew R., Raponi, Mitch , Giordano, Heidi, Maloney, Lara , Isaacson, Jeff, McNeish, Iain A , Swisher, Elizabeth M. , Coleman, Robert L. , Brenton, James D. , Kaufmann, Scott H. , Isaacson, Jeffrey D., Ledermann, Jonathan A.

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: TPS5619-TPS5619

10.1200/jco.2014.32.15_suppl.tps5619 Get It

A new method to analyze adverse events longitudinally in oncology clinical trials.
Thanarajasingam, Gita , Novotny, Paul J. , Loprinzi, Charles L. , Grothey, Axel, Atherton, Pamela J. , Sloan, Jeff A.

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 3622-3622

10.1200/jco.2014.32.15_suppl.3622 Get It

Biologic pathways, candidate genes, and molecular markers associated with quality-of-life domains.
Sloan, Jeff A. , Thong, Melissa S. Y. , Bertels, Meike, Wang, Shelley, Zwinderman, A. H., Weirenga, Eddy, Sprangers, Mirjam A. G. , Barsevick, Andrea Marie , Ordoñana, Juan Ramón , Klepstad, Pål , Singh, Jasvinder A. , Shinozaki, Gen

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 1561-1561

10.1200/jco.2014.32.15_suppl.1561 Get It

Quality of life (QOL) among patients (pts) with HER2+ breast cancer (bc) treated with adjuvant lapatinib and/or trastuzumab in the ALTTO study (BIG 2-06, Alliance N063D).
Kottschade, Lisa A. , Halyard, Michele Y. , Sloan, Jeff A. , Flickinger, Lynn M. , Harris, Lyndsay N. , Le‐Lindqwister, Nguyet, Boyle, Frances , McCaskill-Stevens, Worta J., Zujewski, Jo Anne , Piccart, Martine , Perez, Edith A. , Dueck, Amylou C. , Hillman, David W. , Wolff, Antonio C. , Gralow, Julie R. , Pritchard, Kathleen I. , Ellard, Susan L. , Azambuja, Evandro de , Zujewski, Jo Anne

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 647-647

10.1200/jco.2014.32.15_suppl.647 Get It

A tool to predict post-transcriptional instability related to the dysregulation of the SETD2 histone methyltransferase in renal cell carcinoma (RCC).
Champion, Mia D., Yan, Huihuang , Evans, Jared M., Nie, Jeff, Moore, Raymond M. , Ördög, Tamás , Zhang, Zhiguo , Stewart, A. Keith, Kocher, Jean‐Pierre , Zhang, Zhiguo , Lee, Jeong‐Heon , Davila, Jaime , Joseph, Richard W. , Jonasch, Eric W. , Ho, Thai H.

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 11072-11072

10.1200/jco.2014.32.15_suppl.11072 Get It

Combining survival and toxicity effect sizes from clinical trials into an interpretable, quality-adjusted survival effect size estimate of treatment efficacy.
Sloan, Jeff A. , Major, Brittny , Novotny, Paul J. , Marks, Randolph S., Grothey, Axel , Sargent, Daniel J. , Dueck, Amylou C.

Journal of Clinical Oncology | January 3, 2019 | Volume: 32 | Issue: 15_suppl | Pages: 6630-6630

10.1200/jco.2014.32.15_suppl.6630 Get It