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22 citation(s) found for "Tam, Wayne".

Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML
Swords, Ronan , Maris, Michael B., Zeidner, Joshua F. , Foran, James M. , Cruz, José C. , Tam, Wayne , Vardhanabhuti, Saran , Pawlikowska-Dobler, Iwona , Faessel, Hélène M. , Dash, Ajeeta B. , Sedarati, Farhad , Dezube, Bruce J., Faller, Douglas V. , Swords, Ronan T , Zeidner, Joshua F , Cruz, Jose , Tam, Wayne , Vardhanabhuti, Saran , Pawlikowska-Dobler, Iwona , Dash, Ajeeta B , Sedarati, Farhad , Faller, Douglas V , Savona, Michael R , Coutré, Steven , Erba, Harry Paul , Berdeja, Jesús G. , Savona, Michael R.

Blood | January 18, 2018 | Volume: 131 | Issue: 13 | Pages: 1415-1424

10.1182/blood-2017-09-805895 | PMID 29348128 Get It

Key Points RP2D of PEV 20 mg/m2 in PEV/AZA combo did not alter toxicity profile of AZA; dose-limiting toxicities were transiently elevated AST/ALT. In treatment-naive older AML patients, the intent-to-treat ORR was 50%.
MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program
Xu‐Monette, Zijun Y. , Møller, Michael , Tzankov, Alexandar , Montes‐Moreno, Santiago , Hu, Wenwei , Manyam, Ganiraju C. , Kristensen, Louise , Fan, Lei , Visco, Carlo , Dybkær, Karen , Chiu, April , Tam, Wayne , Zu, Youli , Richards, Kristy L. , Choi, William W.L., Krieken, J. Han van , Huang, Qin , Huh, Jooryung , Ferreri, Andrés J.M. , Zhao, Xiaoying , Bueso‐Ramos, Carlos E. , Wang, Sa A. , Winter, Jane N. , Piris, Miguel Á. , Medeiros, L. Jeffrey , Young, Ken H. , Bhagat, Govind , Hsi, Eric D. , Ai, Weiyun Z. , Ponzoni, Maurilio , Wu, Lin , Go, Ronald S. , Li, Yong , Møller, Michael Boe , Winter, Jane N , Tzankov, Alexandar , Dybkaer, Karen , van Krieken, J Han , Young, Ken H , Piris, Miguel , Medeiros, L Jeffrey , Zu, Youli , Montes-Moreno, Santiago , Xu-Monette, Zijun Y

Blood | August 28, 2013 | Volume: 122 | Issue: 15 | Pages: 2630-2640

10.1182/blood-2012-12-473702 | PMID 23982177 Get It

Key PointsPhenotypic and genotypic profiling of MDM2 in DLBCL. MDM2 as a negative regulator of p53 tumor suppressor function.