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224 citation(s) found for "Ertekin-Taner, Nilufer".

Plasma amyloid β protein is elevated in late-onset Alzheimer disease families
Ertekin‐Taner, Nilüfer , Younkin, Linda H., Yager, Debra, Parfitt, Francine, Younkin, Steven G. , Graff‐Radford, Neill R. , Baker, Matthew , Asthana, Sanjay , Hutton, M.

Neurology | October 3, 2007 | Volume: 70 | Issue: 8 | Pages: 596-606

10.1212/01.wnl.0000278386.00035.21 | PMID 17914065 Get It

P1–353: Associaton of VR22 and LRRTM3 variants with late onset Alzheimer's disease (LOAD) and amyloid beta levels
Ertekin‐Taner, Nilüfer , Allen, Mariet , Younkin, Linda H., Carrasquillo, Minerva M. , Younkin, Samuel , Greene, Matthew H. , Kashino, Mariah R., Singhal, Sita, Petersen, Ronald C. , Graff‐Radford, Neill R. , Younkin, Steven G. , Carrasquillo, Minerva M. , Dincman, Toros A.

Alzheimer's & Dementia | August 17, 2006 | Volume: 2 | Issue: 3S_Part_7 | Pages: No page available

10.1016/j.jalz.2006.05.731 Get It

P1–310: Late onset Alzheimer's disease (LOAD) susceptibility alleles in the insulin–degrading–enzyme gene (IDE) and other Aβ–degrading enzymes
Carrasquillo, Minerva M. , Kashino, Mariah R., Wilcox, Samantha L., Howard, Melissa E., Li, Ma, Zou, Fanggeng, Ertekin‐Taner, Nilüfer , Allen, Mariet , Younkin, Linda H., Petersen, Ronald C. , Younkin, Steven G., Carrasquillo, Minerva M. , Younkin, Samuel , Dincman, Toros A. , Stanton, Chloë M. , Watson, Christopher Mark , Graff, Caroline

Alzheimer's & Dementia | August 17, 2006 | Volume: 2 | Issue: 3S_Part_7 | Pages: No page available

10.1016/j.jalz.2006.05.688 Get It

Linkage of Plasma Aβ42 to a Quantitative Locus on Chromosome 10 in Late-Onset Alzheimer's Disease Pedigrees
Ertekin‐Taner, Nilüfer , Younkin, Linda H., Eckman, Christopher B., Adamson, Jennifer, Hutton, Michael , Younkin, Steven G., Graff, Caroline , Baker, Matthew , Ronald, James , Blangero, John

Science | July 27, 2002 | Volume: 290 | Issue: 5500 | Pages: 2303-2304

10.1126/science.290.5500.2303 | PMID 11125143 Get It

Plasma Aβ42 (amyloid β42 peptide) is invariably elevated in early-onset familial Alzheimer's disease (AD), and it is also increased in the first-degree relatives of patients with typical late-onset AD (LOAD). To detect LOAD loci that increase Aβ42, we used plasma Aβ42 as a surrogate trait and performed linkage analysis on extended AD pedigrees identified through a LOAD patient with extremely high plasma Aβ. Here, we report linkage to chromosome 10 with a maximal lod score of 3.93 at 81 centimorgans close to D10S1225. Remarkably, linkage to the same region was obtained independently in a genome-wide screen of LOAD sibling pairs. These results provide strong evidence for a novel LOAD locus on chromosome 10 that acts to increase Aβ.