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1994 citation(s) found for "Vu, Joshua".

Does Perceived Effort Match Actual Measured Effort During Baseball Long Toss Programs?
Melugin, Heath P. , Conte, Stan, Fealy, Stephen, D’Angelo, John , Larson, Dirk R. , Fleisig, Glenn S. , Dines, Joshua S. , D’Angelo, John, Camp, Christopher L.

Orthopaedic Journal of Sports Medicine | July 29, 2019 | Volume: 7 | Issue: 7_suppl5 | Pages: No page available

10.1177/2325967119s00393 Get It

Objectives: Progressive throwing programs are a mainstay of rehabilitating the throwing athlete after injury or surgery. Athletes are commonly asked to throw at reduced levels of effort (i.e. “50% effort”, ”75%,” etc) to minimize stress to healing tissues. However, it is unknown whether players’ perceived exertion matches actual exertion. The purpose of this study was to determine whether decreased effort correlates with decreased throwing metrics, whether metrics decrease to a predictable degree, and to quantify variability of these metrics within a given athlete when attempting to throw at sub-maximal effort. Methods: Sixty healthy, high school and collegiate baseball pitchers participated in a structured throwing program. After warming up, each pitcher was asked to throw five, max effort long toss throws at a distance of 120 feet. Afterwards, they were asked to give 5 throws at both 75% effort and 50% effort from the same distance. A motusBASEBALL sleeve (Motus Global, Inc.; Massapequa, NY) was worn by all players, which measured arm slot, velocity, shoulder rotation, and elbow varus torque (Nm). Ball velocity was measured in miles per hour (MPH) using a radar gun. The observed changes in throwing metrics were compared to one another across each of the throwing scenarios using a general estimating equation to control for multiple comparisons. They were also compared to the expected change to see if a decrease from 100% effort to 75%, and then to 50% resulted in proportional decreases in elbow torque and ball velocity. Intra-thrower variability was determined for each throwing metric at each degree of effort, and these results are reported using intra-class correlation coefficients (ICC) where an ICC > 0.75 was considered to represent excellent agreement. Results: Mean elbow torque decreased as players decreased their perceived effort from 100% (72.7 Nm) to 75% (67.3 Nm) to 50% (62.s Nm) (p<0.001). Mean ball velocity also decreased as they progressed from 100% effort (77.8 MPH) to 75% effort (66.5) to 50% effort (60.3 MPH) throws (p<0.001). However, these observed decreases in torque and velocity were much smaller in magnitude than the decreases in perceived effort. During the 75% effort throws, torque and velocity were not reduced to 75% of max. Instead, elbow torque was only reduced to 93.3% of max, and velocity dropped to 86.1% of max. Similarly, for the 50% effort throws, torque remained 86.5% of max effort torque, while velocity remained 78.1% of max. Accordingly, for every 25% decrease in perceived effort, torque only decreased 7%, and velocity only decreased 11%. These observed differences were all significantly different than the expected differences (p<0.001 for all). Intra-thrower reliability was considered excellent for all metrics within each throwing scenario: max effort, 75% effort, and 50% effort (ICC>0.75 for all). Conclusion: Measured effort was significantly greater than perceived effort during this standardized throwing program for all metrics tested. This is especially true for ball velocity and varus elbow torque. Ultimately, when players throw at what they perceive to be “reduced effort,” their actual throwing metrics do not decrease at the same rate as their perceived exertion. This has significant implications for throwers during the rehabilitation process as their elbows are likely experiencing more stress than desired. Clinicians and coaches must be aware and may want to consider transitioning to more objective measures of effort during rehabilition.
Flat Ground Throwing Results in Decreased Ball Velocity and Increased Elbow Torque Compared to Mound Throwing
Mcelheny, Kathryn, Ling, Daphne I. , Camp, Christopher L. , Dowling, Brittany , Dines, Joshua S.

Orthopaedic Journal of Sports Medicine | July 29, 2019 | Volume: 7 | Issue: 7_suppl5 | Pages: No page available

10.1177/2325967119s00364 Get It

Objectives: The incidence of shoulder and elbow overuse injury continues to rise in youth baseball players. Several throwing programs designed to reduce stress on the elbow have been described, but most are not evidence-based. The aim of this study was to compare the kinetics and kinematics between mound and flat-ground pitching at two different distances with the goal of developing evidenced-based injury prevention and recovery guidelines for youth throwers. Methods: Fifteen healthy, high school varsity-level baseball pitchers (mean age 16.7 ± 0.7 yrs; height 182.2 ± 6.2 cm; weight 76.0 ± 9.4 kg;) participated in the study. Players were fitted with a motusBASEBALLTM sensor and sleeve (Motus Global, Rockville Centre, NY), which has been shown to have good reliability and correlation with in-laboratory measures. Each pitcher was asked to pitch 5 fastballs to a catcher under each of the 4 conditions: mound at 60.5 ft (regulation distance), flat ground at 60.5 ft, mound at 50.5 ft, and flat ground at 50.5 ft. For each pitch, the sensor recorded arm speed, arm slot, shoulder rotation, and elbow varus torque. Ball velocity was tracked with a radar gun (Stalker Radar, Richardson, TX). Linear mixed-effects models were used to account for both within and between-subject variability. A multivariable model was used to evaluate the association of mound pitching (vs flat ground), distance (50.5 vs 60.5 ft), and their interaction on each of the following outcomes: arm speed, arm slot, shoulder rotation, elbow varus torque, and ball velocity. Results: There were no statistically significant effects of mound vs flat ground or distance variation on both arm speed or shoulder rotation. Arm slot was significantly higher on pitches from the mound at 60.5 ft [+4.58 (95% CI: 1.26, 7.90), p=0.007]. Elbow varus torque was significantly lower on throws from the mound [-1.88 (95% CI: -3.56, -0.20), p=0.03] and from a longer distance [-2.21 (95% CI: -3.89, -0.53), p=0.01]. Pitches thrown from the mound were significantly faster compared to flat ground at both distances, with throws at 60.5 ft of greater velocity than at 50.5 ft [+1.03 (95% CI: 0.66, 1.40), p<0.001]. Please see the Table for full results. Conclusion: The findings suggest that throwing from the mound may not be higher risk compared to flat ground, contrary to long-standing notions. The lower elbow varus torque and higher arm slot, which has previously been shown to be associated with reduced stress, from throwing from the mound may even indicate a protective effect. Compared to 50.5 ft, there was lower elbow varus torque and faster ball velocity at the longer distance, indicating that elbow stress and ball velocity may not correlate perfectly, and radar guns may not be an appropriate surrogate measure of elbow varus torque. A better understanding of the kinetic and kinematic implications of various throwing programs will allow for designing programs that are based on objective data to achieve the goal of preventing injuries in young baseball players. [Table: see text]
Proton beam therapy reirradiation for breast cancer: Multi‐institutional prospective PCG registry analysis
Thorpe, C.S. , Girardo, Marlene , McGee, L.A. , Hartsell, William F. , Larson, Gary, Rossi, Carl J., Rosen, L, Vargas, Carlos , Thorpe, Cameron S , Niska, Joshua R, McGee, Lisa A, Niska, Joshua R. , Kosiorek, Heidi , Tsai, Henry K.

The Breast Journal | July 24, 2019 | Volume: 25 | Issue: 6 | Pages: 1160-1170

10.1111/tbj.13423 | PMID 31338974 Get It

A Prospective Multicenter Study Evaluating Endoscopy Competence Among Gastroenterology Trainees in the Era of the Next Accreditation System
Han, Samuel , Obuch, Joshua , Duloy, Anna , Keswani, Rajesh N. , Simon, Violette C., Ezekwe, Eze, Menard‐Katcher, Paul , Patel, Swati , Aagard, Eva, Brimhall, Bryan , Ahmad, Asyia, Broy, Charles, Carlin, Linda, Connolly, Seán , Cooley, David , Cowley, Kevin, Palma, Jack A. Di, Early, Dayna S., Ellert, Swan , Gaumnitz, Eric A., Ghassemi, Kevin A., Lebovics, Edward, Lee, Robert , Lunsford, Tisha , Massaad, Julia , Mittal, Mohit , Morigeau, Kirsten, Pietrak, Stanley, Piper, Michael , Shah, Anand S. , Shapiro, Alan, Sonnier, William, Sorrell, Cari, Vignesh, Shivakumar , Woolard, Shani, Wani, Sachin , Hall, Matt , Alghamdi, Saad Ali , Brown, Michael D. , Chugh, Priyanka , Connolly, Sean E., Cooley, D. Matthew

Academic Medicine | July 21, 2019 | Volume: 95 | Issue: 2 | Pages: 283-292

10.1097/acm.0000000000002885 | PMID 31335810 Get It

Purpose The Next Accreditation System requires training programs to demonstrate competence among trainees. Within gastroenterology (GI), there are limited data describing learning curves and structured assessment of competence in esophagogastroduodenoscopy (EGD) and colonoscopy. In this study, the authors aimed to demonstrate the feasibility of a centralized feedback system to assess endoscopy learning curves among GI trainees in EGD and colonoscopy. Method During academic year 2016–2017, the authors performed a prospective multicenter cohort study, inviting participants from multiple GI training programs. Trainee technical and cognitive skills were assessed using a validated competence assessment tool. An integrated, comprehensive data collection and reporting system was created to apply cumulative sum analysis to generate learning curves that were shared with program directors and trainees on a quarterly basis. Results Out of 183 fellowships invited, 129 trainees from 12 GI fellowships participated, with an overall trainee participation rate of 72.1% (93/129); the highest participation level was among first-year trainees (90.9%; 80/88), and the lowest was among third-year trainees (51.2%; 27/53). In all, 1,385 EGDs and 1,293 colonoscopies were assessed. On aggregate learning curve analysis, third-year trainees achieved competence in overall technical and cognitive skills, while first- and second-year trainees demonstrated the need for ongoing supervision and training in the majority of technical and cognitive skills. Conclusions This study demonstrated the feasibility of using a centralized feedback system for the evaluation and documentation of trainee performance in EGD and colonoscopy. Furthermore, third-year trainees achieved competence in both endoscopic procedures, validating the effectiveness of current training programs.
Reconstruction of the Medial Ulnar Collateral Ligament of the Elbow: Biomechanical Comparison of a Novel Anatomic Technique to the Docking Technique
Bernard, Christopher D. , Benavitz, Bill, Konicek, John , Altchek, David W. , Dines, Joshua S. , Camp, Christopher L.

Orthopaedic Journal of Sports Medicine | July 17, 2019 | Volume: 7 | Issue: 7 | Pages: No page available

10.1177/2325967119857592 | PMID 31763343 Get It

Background: In recent years, understanding of the anatomy of the ulnar collateral ligament (UCL) has evolved, demonstrating that the insertional footprint of the UCL on the ulna is more elongated and distally tapered than previously described. Current UCL reconstruction configurations do not typically re-create this native anatomy, which may represent a potential area for improvement. Purpose/Hypothesis: The purposes of this study were (1) to describe a novel anatomic UCL reconstruction technique designed to better replicate the native UCL anatomy and (2) to biomechanically compare this with the docking technique. The hypothesis was that the ultimate load to failure for the anatomic technique would not be inferior to the docking technique. Study Design: Controlled laboratory study. Methods: A total of 16 fresh-frozen cadaveric upper extremities (8 matched pairs) were utilized. One elbow in each pair was randomized to receive UCL reconstruction via the docking technique or the novel anatomic UCL reconstruction technique with palmaris tendon autograft. Following reconstruction, biomechanical testing was performed by applying valgus rotational torque at a constant rate of 5 deg/s until ultimate mechanical failure of the construct occurred. Maximal torque (N·m), rotation stiffness (N·m/deg), and mode/location of failure were recorded for each specimen. Results: The mean ultimate load to failure for elbows in the docking technique group was 23.8 ± 6.1 N·m, as compared with 31.9 ± 8.4 N·m in the anatomic technique group ( P = .045). Mean rotational stiffness was 1.9 ± 0.7 versus 2.3 ± 0.9 N·m/deg for the docking and anatomic groups, respectively ( P = .338). The most common mode of failure was suture pullout from the graft, which occurred in all 8 (100%) docking technique specimens and 7 of 8 (88%) specimens that underwent the anatomic UCL reconstruction technique. Conclusion: Ultimately, the anatomic UCL reconstruction technique demonstrated superior strength and resistance to valgus torque when compared with the docking technique, and this was comparable with that of the native UCL from prior studies. Increased initial strength may allow for earlier initiation of throwing postoperatively and potentially shorten return-to-play times. Clinical Relevance: Current UCL reconstruction techniques do not accurately reproduce the UCL insertional anatomy on the ulna. The novel anatomic technique described may result in more natural joint kinematics. This study demonstrated load-to-failure rates that are significantly higher than with the docking technique and consistent with the native ligament, as reported from previous studies. These findings may serve as a foundation for future clinical study and optimization of this technique.
Impaired central hemodynamics in chronic obstructive pulmonary disease during submaximal exercise
Smith, Joshua R. , Johnson, Bruce D. , Olson, Thomas P. , Smith, Joshua R

Journal of Applied Physiology | July 11, 2019 | Volume: 127 | Issue: 3 | Pages: 691-697

10.1152/japplphysiol.00877.2018 | PMID 31295068 Get It

It is unknown whether central hemodynamics are impaired during exercise in chronic obstructive pulmonary disease (COPD) patients. We hypothesized that, at a similar absolute V̇o2 during exercise, COPD patients would have a lower stroke volume and cardiac output compared with healthy controls. Furthermore, we hypothesized that greater static hyperinflation [ratio of inspiratory capacity to total lung capacity (IC/TLC)] and expiratory intrathoracic pressure would be significantly related to the lower cardiac output and stroke volume responses in COPD patients. Clinically stable COPD ( n = 13; FEV1/FVC: 52 ± 13%) and controls ( n = 10) performed constant workload submaximal exercise at an absolute V̇o2 of ~1.3 L/min. During exercise, inspiratory capacity maneuvers were performed to determine operating lung volumes and cardiac output (via open-circuit acetylene rebreathe technique) and esophageal pressure were measured. At similar absolute V̇o2 during exercise ( P = 0.81), COPD had lower cardiac output than controls (COPD: 11.0 ± 1.6 vs. control: 12.2 ± 1.2 L/min, P = 0.03) due to a lower stroke volume (COPD: 107 ± 13 vs. control: 119 ± 19 mL, P = 0.04). The heart rate response during exercise was not different between groups ( P = 0.66). FEV1 (%predicted) and IC/TLC were positively related to stroke volume ( r = 0.68, P = 0.01 and r = 0.77, P < 0.01). Last, esophageal pressure-time integral during inspiration was positively related to cardiac output ( r = 0.56, P = 0.047). These data demonstrate that COPD patients have attenuated cardiac output and stroke volume responses during exercise compared with control. Furthermore, these data suggest that the COPD patients with the most severe hyperinflation and more negative inspiratory intrathoracic pressures have the most impaired central hemodynamic responses. NEW & NOTEWORTHY Chronic obstructive pulmonary disease leads to cardiac structural changes and pulmonary derangements that impact the integrative response to exercise. However, it is unknown whether these pathophysiological alterations influence the cardiac response during exercise. Herein, we demonstrate that COPD patients exhibit impaired central hemodynamics during exercise that are worsened with greater hyperinflation.
Assessment of complement interference in anti-Müllerian hormone immunoassays
Turner, Katherine A., Larson, Bethany J., Kreofsky, Nina C., Bornhorst, Joshua A. , Bornhorst, Joshua , Willrich, Maria Alice V. , Algeciras‐Schimnich, Alicia

Clinical Chemistry and Laboratory Medicine (CCLM) | July 11, 2019 | Volume: 58 | Issue: 1 | Pages: e8-e10

10.1515/cclm-2019-0496 | PMID 31815379 Get It

Thromboembolic Risk of 4-Factor Prothrombin Complex Concentrate versus Fresh Frozen Plasma for Urgent Warfarin Reversal in the Emergency Department
Maguire, Michelle, Fuh, Lanting , Marshall, Ariela L. , Levine, Michael , Howell, Melissa, Perry, Blair A., Hayes, Bryan D. , Marshall, Ariela , Goldstein, Joshua Norkin , Rosovsky, Rachel

Western Journal of Emergency Medicine | July 9, 2019 | Volume: 20 | Issue: 4 | Pages: 619-625

10.5811/westjem.2019.4.41649 | PMID 31316701 Get It

Patient care without borders: a systematic review of medical and surgical tourism
Foley, Brittany M., Haglin, Jack M. , Eltorai, Adam E. M. , Tanzer, Joshua Ray

Journal of Travel Medicine | July 4, 2019 | Volume: 26 | Issue: 6 | Pages: No page available

10.1093/jtm/taz049 | PMID 31281926 Get It

Abstract Background Medical tourism (MT) is an increasingly utilized modality for acquiring medical treatment for patients globally. This review assimilates the current literature regarding MT, with particular focus on the applications, ethics and economics. Methods A systematic review of MEDLINE and PubMed Central databases for publications relating to MT from 2005 to 2018 yielded 43 articles for this review. Results Patients seeking elective bariatric, cosmetic and orthopedic surgery abroad are motivated by significantly lower costs, all-inclusive vacation packages and reduced wait times. Complication rates as high as 56% include infection, poor aesthetic and functional outcome and adverse cardiovascular events. Cross-border reproductive care has steadily increased due to less restrictive policies in select countries; however, the depth of research on outcomes and quality of care is abysmal. Stem cell therapy promise treatments that are often not well researched and offer minimal evidence of efficacy, yet patients are drawn to treatment through anecdotal advertisements and a last sense of hope. Transplant surgery sought to decrease wait times carries many of the similar aforementioned risks and may contribute to the practice of organ trafficking in countries with high rates of poverty. Patients and countries alike are motivated by a plethora of factors to engage in the MT industry but may be doing so without accurate knowledge of the quality, safety or potential for economic gain. Safety is of utmost importance to prevent surgical complications and the spread of treatment-resistant bacteria. Conclusions MT is growing in popularity and complexity. The lack of standardization in its definition and regulation leads to difficulty in epidemiologic and economic analysis and ethical issues of informed consent and health equity. The findings of this review may be used by the stakeholders of MT, including patients and providers, to enhance informed decision-making and quality of care.
Health Misinformation and the Power of Narrative Messaging in the Public Sphere
Murdoch, Blake , Brown, Jasmine M., Perrault, Sarah Tinker, Jarry, Jonathan, Anthony, Samantha J. , Ogbogu, Ubaka , Greenberg, Joshua , Zarzeczny, Amy , Hyde-Lay, Robyn, Caulfield, Timothy , Marcon, Alessandro R , Snyder, Jeremy , Brooks, Stephanie P. , Master, Zubin , Rachul, Christen M.

Canadian Journal of Bioethics | June 18, 2019 | Volume: 2 | Issue: 2 | Pages: 52-60

10.7202/1060911ar Get It

Numerous social, economic and academic pressures can have a negative impact on representations of biomedical research. We review several of the forces playing an increasingly pernicious role in how health and science information is interpreted, shared and used, drawing discussions towards the role of narrative. In turn, we explore how aspects of narrative are used in different social contexts and communication environments, and present creative responses that may help counter the negative trends. As traditional methods of communication have in many ways failed the public, changes in approach are required, including the creative use of narratives.