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1175 citation(s) found for "Ha, Alex".

Epidural Hematoma Following Cervical Spine Surgery
Schroeder, Gregory D. , Hilibrand, Alan S. , Fish, David E., Wang, Jeffrey C. , Smith, Zachary A. , Hsu, Wellington K. , Gokaslan, Ziya L. , Isaacs, Robert E., Kanter, Adam S. , Mroz, Thomas E. , Sasso, Rick C., Fehlings, Michael G. , Buser, Zorica , Bydon, Mohamad , Cha, Peter I., Chatterjee, Dhananjay, Gee, Erica L., Lord, Elizabeth L. , Mayer, Erik N. , McBride, Owen J., Nguyen, Emily C., Roe, Allison K. , Tortolani, P. Justin, Stroh, D. Alex, Yanez, Marisa Y., Arnold, Paul M. , Gum, Jeffrey L. , Nassr, Ahmad , Cha, Peter I., Riew, Kiehyun Daniel , Fehlings, Michael G

Global Spine Journal | April 19, 2017 | Volume: 7 | Issue: 1_suppl | Pages: 120S-126S

10.1177/2192568216687754 | PMID 28451483 Get It

Study Design: A multicentered retrospective case series. Objective: To determine the incidence and circumstances surrounding the development of a symptomatic postoperative epidural hematoma in the cervical spine. Methods: Patients who underwent cervical spine surgery between January 1, 2005, and December 31, 2011, at 23 institutions were reviewed, and all patients who developed an epidural hematoma were identified. Results: A total of 16 582 cervical spine surgeries were identified, and 15 patients developed a postoperative epidural hematoma, for a total incidence of 0.090%. Substantial variation between institutions was noted, with 11 sites reporting no epidural hematomas, and 1 site reporting an incidence of 0.76%. All patients initially presented with a neurologic deficit. Nine patients had complete resolution of the neurologic deficit after hematoma evacuation; however 2 of the 3 patients (66%) who had a delay in the diagnosis of the epidural hematoma had residual neurologic deficits compared to only 4 of the 12 patients (33%) who had no delay in the diagnosis or treatment ( P = .53). Additionally, the patients who experienced a postoperative epidural hematoma did not experience any significant improvement in health-related quality-of-life metrics as a result of the index procedure at final follow-up evaluation. Conclusion: This is the largest series to date to analyze the incidence of an epidural hematoma following cervical spine surgery, and this study suggest that an epidural hematoma occurs in approximately 1 out of 1000 cervical spine surgeries. Prompt diagnosis and treatment may improve the chance of making a complete neurologic recovery, but patients who develop this complication do not show improvements in the health-related quality-of-life measurements.
Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE ε4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene
Valla, Jon, Yaari, R. , Wolf, Andrew B. , Kusne, Yael , Beach, Thomas G. , Roher, Alex E., Corneveaux, Jason J., Huentelman, Matthew J. , Caselli, Richard J. , Reiman, Eric M.

Journal of Alzheimer's Disease | April 5, 2017 | Volume: 22 | Issue: 1 | Pages: 307-313

10.3233/jad-2010-100129 | PMID 20847408 Get It

A pooled analysis of demographic characteristics and clinical outcomes of phase I oncology clinical trials, the Mayo Clinic experience
Atherton, Pamela J. , Jasperson, Britta, Sloan, Jeffrey A., Mandrekar, Sumithra J. , Smith, Denise J., Erlichman, Charles , Adjei, Alex A.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 9724-9724

10.1200/jco.2004.22.90140.9724 Get It

Complementary and alternative medicine (CAM) use by patients enrolled in phase I clinical trials
Mandrekar, Sumithra J. , Dy, Grace K. , Furth, Alfred, Bekele, Lishan, Hanson, L., Sloan, Jeff A. , Adjei, Alex A.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 8053-8053

10.1200/jco.2004.22.90140.8053 Get It

Oral topotecan and intravenous carboplatin with G-CSF support in previously treated patients with extensive stage small cell lung cancer: A phase II trial of the North Central Cancer Treatment Group
Jett, James R., Mattar, B., Hillman, Shauna L., Kugler, J. W., Michalak, J C, Adjei, Alex A. , Johnson, Elizabeth Anne

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 7203-7203

10.1200/jco.2004.22.90140.7203 Get It

Pemetrexed (Pem)/gemcitabine (Gem) as front-line therapy for advanced NSCLC: A randomized, phase II trial of three schedules
Adjei, Alex A. , Nair, S., Reuter, Nicholas F., Mandrekar, Sumithra J. , Kuross, Steven A., Rowland, K. M., Steen, Preston D. , Hillman, Shauna L., Jett, James R., Nair, S., Schild, Steven E.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 7070-7070

10.1200/jco.2004.22.90140.7070 Get It

The Results of combined modality therapy for limited stage small cell lung cancer (LD-SCLC) in the elderly
Stella, Philip J., Brooks, Burke J., Mandrekar, Sumithra J. , Bonner, James A. , McGinnis, William L., Nikcevich, Daniel A., Adjei, Alex A. , Jatoi, Aminah , Jett, James R., Schild, Steven E.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 7043-7043

10.1200/jco.2004.22.90140.7043 Get It

A phase II study of a combination of pemetrexed (Pem) and gemcitabine (Gem) in patients with metastatic breast cancer (MBC): An NCCTG study
X., C., Steen, Preston D. , Rowland, K. M., Niedringhaus, Robert D., Kugler, J. W., Perez, Edith A. , Adjei, Alex A. , Ma, C. X., Ingle, James N.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 639-639

10.1200/jco.2004.22.90140.639 Get It

A phase I trial of gemcitabine (Gem), 17-allylaminogeldanamycin (17-AAG) and cisplatin (CDDP) in solid tumor patients
Toft, D O, Steinmetz, Susan , Furth, Alfred, Mandrekar, Sumithra J. , Stensgard, Bridget, McCollum, Andrea K., Hanson, L., Adjei, Alex A. , Erlichman, Charles , Haluska, Paul

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 3058-3058

10.1200/jco.2004.22.90140.3058 Get It

Phase I trial of OSI-774 and CPT-11 in patients with advanced solid tumors
Rao, Ravi D., Furth, Alfred, Mandrekar, Sumithra J. , Adjei, Alex A. , Ames, Matthew M. , Erlichman, Charles , Pitot, Henry C., Reid, Joel M. , Goetz, Matthew P. , Safgren, Stephanie L.

Journal of Clinical Oncology | April 5, 2017 | Volume: 22 | Issue: 14_suppl | Pages: 3053-3053

10.1200/jco.2004.22.90140.3053 Get It