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Gulbrandsen, Trevor R.

https://orcid.org/0000-0002-6108-3351

Mayo Clinic

University of Iowa Hospitals and Clinics

Citations 2

Preoperative Opioid Usage, Male Sex, and Preexisting Knee Osteoarthritis Impacts Opioid Refills After Isolated Arthroscopic Meniscectomy: A Population‐Based Study
Khazi, Zain , Baron, Jacqueline , Shamrock, Alan G. , Gulbrandsen, Trevor R. , Bedard, Nicholas A. , Wolf, Brian R. , Duchman, Kyle R. , Westermann, Robert W. , Bedard, Nicolas, Bedard, Nicholas A

Arthroscopy | May 10, 2020 | Volume: 36 | Issue: 9 | Pages: 2478-2485

10.1016/j.arthro.2020.04.039 Get It

Purpose To identify risk factors for opioid consumption after arthroscopic meniscectomy using a large national database. Methods Patients undergoing primary arthroscopic meniscectomy from 2007 to 2016 were retrospectively accessed from the Humana database. Patients were categorized as those who filled opioid prescriptions within 3 months (OU), within 1 month (A‐OU), between 1 and 3 months (C‐OU), and never filled opioid prescriptions (N‐OU) before surgery. Rates of opioid use were evaluated preoperatively and longitudinally tracked for each cohort. Prolonged opioid use was defined as continued opioid prescription filling at ≥3 months after surgery. Multiple logistic regression analysis was used to identify factors associated with opioid refills at 12 months after surgery. Results There were 88,120 patients (53.7% female) who underwent arthroscopic meniscectomy, of whom 46.1% (n = 39,078) were N‐OU. About a quarter (25.3%) of patients continued filling opioid prescriptions at 1 year postoperatively. In addition, opioid fill rate at 1 year was significantly greater in the OU group compared with the N‐OU group with a relative risk of 2.89 (40.7% vs 14.1%; 95% confidence interval 2.81‐2.98; P < .0001). Multiple logistic regression model identified C‐OU (odds ratio 3.67; 95% confidence interval 3.53‐3.82; P < .0001) as the strongest predictor of opioid use at 12 months postoperatively. Furthermore, male sex, A‐OU, knee osteoarthritis, diabetes mellitus, hypertension, chronic obstructive pulmonary disease, fibromyalgia, anxiety or depression, alcohol use disorder, and tobacco use ( P < .02 for all) had significantly increased odds of opioid use at 12 months postoperatively. However, patients <40 years ( P < .0001) had significantly decreased odds of opioid use 12 months postoperatively. Conclusions Preoperative opioid filling is a significant risk factor for opioid use at 12 months postoperatively. Male sex, preexisting knee osteoarthritis, and diagnosis of anxiety or depression were independent risk factors for opioid use 12 months following arthroscopic meniscectomy. Level of Evidence Level‐III, Retrospective Cohort Study.
Biomechanical Evaluation of Suture Anchor versus Transosseous Tunnel Patellar Tendon Repair Techniques
Sherman, Seth L. , Black, Brandee S., Mooberry, Matthew A., Freeman, Katie L., Gulbrandsen, Trevor R. , Milles, Jeffrey L., Evans, Laura , Flood, David, Mooberry, Matthew, Evans, Laura, Pfeiffer, Ferris M.

The Journal of Knee Surgery | September 6, 2018 | Volume: 32 | Issue: 08 | Pages: 825-832

10.1055/s-0038-1669790 Get It

Abstract The objective of this study is to compare the cyclic loading strength and ultimate failure load in suture anchor repair versus transosseous tunnel repair of patellar tendons using a cadaver model. Twelve cadaveric patella specimens were used (six matched pairs). Dual-energy X-ray absorptiometry (DXA) measurements were performed to ensure equal bone quality among groups. All right knees were assigned to the suture anchor repair group (n = 6), whereas all left knees were assigned to the transosseous bone tunnel group (n = 6). Suture type and repair configuration were equivalent. After the respective procedures were performed, each patella was mounted into a gripping jig. Tensile load was applied at a rate of 1 Hz between magnitudes of 50 and 150 N, 50 and 200 N, 50 and 250 N, and tensile load at a rate of 0.1 mm/s until failure. Failure was defined as a sharp deviation in the linear load versus displacement curve, and failure mode was recorded. DXA measurements demonstrated equivalence of bone quality between the two groups (p > 0.05). During cyclic load testing, there was only a statistically significant difference between the groups with regard to cyclic loading at the 50 to 200 N loading cycle (p = 0.010). There was no statistically significant difference between the groups with regard to ultimate load to failure (p = 0.43). Failure mode within the suture anchor cohort occurred through anchor pullout except for one, which failed through the tendon. All specimens within the transosseous cohort failed through the midsubstance of the tendon except for one, which failed through suture breakage. Suture anchor repair demonstrated a similar biomechanical profile regarding cyclic loading and ultimate load to failure when compared with “gold standard” transosseous tunnel patellar tendon repair with a trend toward less gapping in the suture anchor group. Using suture anchors for repair of the patella tendon has similar biomechanical properties to transpatellar tunnels but may provide other clinical advantages.