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Goepfert, Helmuth

Mayo Clinic

University of Texas System Cancer Center Houston Texas

Citations 2

Immunologic Detection of Occult Primary Cancer of the Head and Neck
Neel, H. Bryan, Pearson, Gary R., Weiland, Louis H., Taylor, William F., Goepfert, Helmuth

Otolaryngology–Head and Neck Surgery | January 5, 2017 | Volume: 89 | Issue: 2 | Pages: 230-234

10.1177/019459988108900217 Get It

Because antibody titers against Epstein‐Barr virus (EBV) antigens often are elevated in patients with active undifferentiated and nonkeratinizing nasopharyngeal carcinoma, anti‐EBV serologic tests have been applied as a diagnostic aid in patients who have metastatic lymphadenopathy in the neck without an obvious source. In this study of 44 patients, the serologic testing procedure proved useful in identifying six patients with nasopharyngeal carcinoma that was initially occult but was eventually confirmed by biopsy.