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Sretenović, Aleksandar

https://orcid.org/0009-0008-1868-7695

Mayo Clinic

University Children's Hospital, Belgrade

Citations 1

Impact of bowel management in alleviating symptoms of urinary incontinence in patients with spina bifida associated with overactive bladder and detrusor sphincter dyssynergia
Radojicic, Zoran , Milivojević, Saša , Milić, Nataša , Milin‐Lazović, Jelena , Lukač, Marija , Sretenović, Aleksandar , Milic, N

BJU International | May 26, 2018 | Volume: 123 | Issue: 1 | Pages: 118-123

10.1111/bju.14414 Get It

Objective To examine the effects of bowel management on urinary incontinence in patients with spina bifida associated with overactive bladder ( OAB ) and detrusor sphincter dyssynergia ( DSD ). Materials and Methods The research was carried out during the period 2014–2017. A total of 35 patients (group 1) were administered bowel management combined with anticholinergic medication therapy and clean intermittent catheterization ( CIC ) and 35 patients (group 2) were treated only with anticholinergic medication therapy and CIC . Bowel management included daily enema, laxative application and a special diet, with the aim of treating constipation, evaluated according to the Roma III criteria and echosonographically determined transversal rectal diameter. The effects of the administered bowel management on urinary incontinence were assessed according to the mean dry interval between two CIC s for all patients. All patients were followed up for 1 year, during which data were prospectively collected. Results There was no statistically significant difference with regard to age, gender and baseline clinical features between the two groups. In group 1, the mean ± sd dry interval between two CIC s was 150.0 ± 36.4 min, and group 2 it was 101.3 ± 51.6 min. There was a significant difference in urinary incontinence, i.e. in the mean dry interval, between the two groups ( P < 0.001). Conclusion Administering bowel management considerably increased the mean dry interval, thus greatly alleviating the symptoms of urinary incontinence. For this reason, bowel management should form an integral part of the treatment of patients with spina bifida and OAB and DSD .