Back to Authors

Kantarci, Kejal

https://orcid.org/0000-0002-8001-2081

Mayo Clinic

Mayo Clinic

Citations 648

IC‐P‐028: CogState computerized testing is associated with amyloid and FDG‐PET: Implications for secondary preventive trials
Wiste, Heather J. , Weigand, Stephen D. , Lowe, Val J. , Roberts, Rosebud O., Petersen, Ronald C. , Mielke, Michelle M. , Vemuri, Prashanthi , Machulda, Mary M. , Knopman, David S. , Kantarci, Kejal , Geda, Yonas E. , Boeve, Bradley F. , Jack, Clifford R.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2013.05.029 Get It

P3–093: FDG‐PET and PiB‐PET imaging in asymptomatic at‐risk carriers of a novel octapeptide repeat insertion in PRNP
Lowe, Val J. , Przybelski, Scott A. , Weigand, Stephen D. , Spychalla, Anthony J., Jones, David, Kumar, Neeraj , Rademakers, Rosa , Petersen, Ronald, Parisi, Joseph, Boeve, Bradley F. , Kantarci, Kejal , Vemuri, Prashanthi , Jones, David, McDade, Eric , Baker, Matthew , Knopman, David S. , Petersen, Ronald, Dickson, Dennis W. , Jack, Clifford R.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_14 | Pages: No page available

10.1016/j.jalz.2013.05.1163 Get It

IC‐P‐073: Aberrant tau and amyloid pathology underlies 1H MR spectroscopic alterations in Alzheimer's disease and Lewy body disease
Murray, Melissa E. , Przybelski, Scott A. , Lesnick, Timothy G. , Liesinger, Amanda M., Spychalla, Anthony J., Gunter, Jeffrey L. , Parisi, Joseph, Petersen, Ronald, Boeve, Bradley F. , Knopman, David S. , Petersen, Ronald, Dickson, Dennis W. , Kantarci, Kejal , Murray, Melissa E

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2013.05.070 Get It

IC‐P‐060: MRS differentiates MCI patients who progress to dementia with Lewy bodies and Alzheimer's disease
Zhang, Bing , Maroney‐Smith, Mandie, Petersen, Ronald C. , Ferman, Tanis J. , Boeve, Bradley F. , Smith, Glenn E. , Knopman, David S. , Jack, Clifford R. , Kantarci, Kejal

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2013.05.056 Get It

Microbleeds in the logopenic variant of primary progressive aphasia
Whitwell, Jennifer L. , Gunter, Jeffrey L. , Senjem, Matthew L. , Murphy, Matthew C. , Kantarci, Kejal , Lowe, Val J. , Josephs, Keith A. , Jack, Clifford R. , Duffy, Joseph R. , Strand, Edythe A. , Machulda, Mary M. , Senjem, Matthew L , Kantarci, Kejal

Alzheimer's & Dementia | April 4, 2013 | Volume: 10 | Issue: 1 | Pages: 62-66

10.1016/j.jalz.2013.01.006 Get It

Abstract Background Microbleeds have been associated with Alzheimer's disease (AD), although it is unclear whether they occur in atypical presentations of AD, such as the logopenic variant of primary progressive aphasia (lvPPA). We aimed to assess the presence and clinical correlates of microbleeds in lvPPA. Methods Thirteen lvPPA subjects underwent 3T T2*‐weighted and fluid‐attenuated inversion recovery magnetic resonance imaging and Pittsburgh compound B (PiB) positron emission tomography imaging. Microbleeds were identified on manual review and assigned a regional location. Total and regional white matter hyperintensity (WMH) burden was measured. Results Microbleeds were observed in four lvPPA subjects (31%), most commonly in the frontal lobe. Subjects with microbleeds were older, more likely female, and had a greater burden of WMH than those without microbleeds. The regional distribution of microbleeds did not match the regional distribution of WMH. All cases were PiB positive. Conclusions Microbleeds occur in approximately one third of subjects with lvPPA, with older women at the highest risk.
Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women
Raz, Limor , Jayachandran, Muthuvel , Tosakulwong, Nirubol , Lesnick, Timothy G. , Wille, Samantha, Murphy, Matthew C. , Senjem, Matthew L. , Gunter, Jeffrey L. , Vemuri, Prashanthi , Miller, Virginia M. , Kantarci, Kejal , Jack, Clifford R. , Vemuri, Prashanthi , Senjem, Matthew L , Kantarci, Kejal

Neurology | February 14, 2013 | Volume: 80 | Issue: 10 | Pages: 911-918

10.1212/wnl.0b013e3182840c9f Get It

Focal hemosiderin deposits and β‐amyloid load in the ADNI cohort
Kantarci, Kejal , Gunter, Jeffrey L. , Tosakulwong, Nirubol , Weigand, Stephen D. , Senjem, Matthew S., Petersen, Ronald C. , Aisen, Paul, Jagust, William J. , Weiner, Michael W. , Initiative, Alzheimer's Disease Neuroimaging, Senjem, Matthew L. , Senjem, Matthew S., Jack, Clifford R. , Initiative, Alzheimer's Disease Neuroimaging, Senjem, Matthew L , Kantarci, Kejal

Alzheimer's & Dementia | January 30, 2013 | Volume: 9 | Issue: 5S | Pages: No page available

10.1016/j.jalz.2012.10.011 Get It

BackgroundPrevalence and risk factors for focal hemosiderin deposits are important considerations when planning amyloid‐modifying trials for treatment and prevention of Alzheimer's disease (AD).MethodsSubjects were cognitively normal (n = 171), early‐mild cognitive impairment (MCI) (n = 240), late‐MCI (n = 111), and AD (n = 40) from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Microhemorrhages and superficial siderosis were assessed at baseline and on all available MRIs at 3, 6, and 12 months. β‐amyloid load was assessed with 18F‐florbetapir positron emission tomography.ResultsPrevalence of superficial siderosis was 1% and prevalence of microhemorrhages was 25% increasing with age (P < .001) and β‐amyloid load (P < .001). Topographic densities of microhemorrhages were highest in the occipital lobes and lowest in the deep/infratentorial regions. A greater number of microhemorrhages at baseline was associated with a greater annualized rate of additional microhemorrhages by last follow‐up (rank correlation = 0.49; P < .001).ConclusionsFocal hemosiderin deposits are relatively common in the ADNI cohort and are associated with β‐amyloid load.