Citations 2
Computer versus Compensatory Calendar Training in Individuals with Mild Cognitive Impairment: Functional Impact in a Pilot Study
Chandler, Melanie , Duncan, Noah, Hanna, Sherrie , Cuc, Andrea , Fields, Julie A. , Hoffman‐Snyder, Charlene , Lunde, Angela , Chandler, Melanie J, Locke, Dona E.C. , Hanna, Sherrie M, Cuc, Andrea V , Hoffman Snyder, Charlene R, Lunde, Angela M, Smith, Glenn E.
Brain Sciences | September 6, 2017 | Volume: 7 | Issue: 9 | Pages: 112
This pilot study examined the functional impact of computerized versus compensatory calendar training in cognitive rehabilitation participants with mild cognitive impairment (MCI). Fifty-seven participants with amnestic MCI completed randomly assigned calendar or computer training. A standard care control group was used for comparison. Measures of adherence, memory-based activities of daily living (mADLs), and self-efficacy were completed. The calendar training group demonstrated significant improvement in mADLs compared to controls, while the computer training group did not. Calendar training may be more effective in improving mADLs than computerized intervention. However, this study highlights how behavioral trials with fewer than 30–50 participants per arm are likely underpowered, resulting in seemingly null findings.
A pilot randomized trial of two cognitive rehabilitation interventions for mild cognitive impairment: caregiver outcomes
Cuc, Andrea , Duncan, Noah, Fields, Julie A. , Hoffman‐Snyder, Charlene , Hanna, Sherrie , Lunde, Angela , Chandler, Melanie , Cuc, Andrea V , Locke, Dona E.C. , Snyder, Charlene Hoffman, Smith, Glenn E.
International Journal of Geriatric Psychiatry | February 24, 2017 | Volume: 32 | Issue: 12 | Pages: No page available
ObjectiveThis study aims to provide effect size estimates of the impact of two cognitive rehabilitation interventions provided to patients with mild cognitive impairment: computerized brain fitness exercise and memory support system on support partners' outcomes of depression, anxiety, quality of life, and partner burden.MethodsA randomized controlled pilot trial was performed.ResultsAt 6 months, the partners from both treatment groups showed stable to improved depression and anxiety scores, while partners in an untreated control group showed worsening depression and anxiety over 6 months. There were no statistically significant differences on quality of life or burden outcomes in this small pilot trial; however, effect sizes were moderate, suggesting that the sample sizes in this pilot study were not adequate to detect statistical significance.ConclusionEither form of cognitive rehabilitation may help partners' mood or anxiety, compared with providing no treatment. However, effect size estimates related to other partner outcomes (i.e., burden, quality of life) suggest that follow‐up efficacy trials will need sample sizes of at least 30–100 people per group to accurately determine significance. Copyright © 2017 John Wiley & Sons, Ltd.