Citations 2
Pulmonologists’ and Primary Care Physicians’ Responses to an Adult Patient with Asthma Who Inquires about Using Electronic Cigarettes as a Smoking Cessation Tool
Nickels, Andrew S., Jenkins, Sarah M. , Tilburt, Jon C. , Hays, J. Taylor , Warner, David O.
Annals of the American Thoracic Society | March 1, 2017 | Volume: 14 | Issue: 3 | Pages: 466-468
Can Parents Refuse a Potentially Lifesaving Transplant for Severe Combined Immunodeficiency?
Nickels, Andrew S., Myers, Gary Douglas , Joshi, Avni Y. , Sharp, Richard R. , Lantos, John D. , Johnson, Liza‐Marie , Sharp, Richard R
Pediatrics | June 15, 2016 | Volume: 138 | Issue: 1 | Pages: No page available
If untreated, most children with severe combined immunodeficiency disorder (SCID) will die of complications of infection within the first 2 years of life. Early hematopoietic stem cell transplant (HSCT) is the current standard of care for this disease. Although potentially lifesaving, prognosis of HSCT in SCID is variable depending on a number of host and donor factors. Of the survivors, many develop secondary problems such as chronic graft-versus-host disease or even second malignancies. Posttransplant care is complex and requires great effort from parents to adhere to difficult treatment regimens. In this article, we address the difficult ethical question of what to do if parents choose not to have their child with SCID undergo HSCT but prefer palliative care.