Citations 3
Clinical characteristics of infantile hemangiomas with aggressive, persistent, and destructive ulceration
Gautam, Ayushi , Frieden, Ilona J. , Shah, Sonal D. , Witman, Patricia M., Harfmann, Katya , Bradley, Flora , Blei, Francine , Pope, Elena , Alsumait, Anwar, Gupta, Deepti , Covelli, Isabela, Streicher, Jenna L., Cotton, Colleen , Tollefson, Megha M. , Nguyen, Henry, Hunt, Raegan , Buros, Amy, Fernandez Faith, Esteban , Gautam, Ayushi , Buros, Amy, Faith, Esteban Fernández
Pediatric Dermatology | October 17, 2023 | Volume: 40 | Issue: 6 | Pages: 996-1002
AbstractBackground/ObjectivesUlceration is a common complication of infantile hemangioma (IH). Severe, persistent ulceration occurs in a minority of patients. This study aims to characterize the clinical features of IH with aggressive ulceration (AU).MethodsMulticenter retrospective study of clinical features of IH with AU.ResultsThirty‐five patients with AU were identified and included in the study. The majority of AU occurred in segmental IH (23/35, 65%). Segmental IH with AU were large (≥10 cm2; 16/23, 69%, p < .001) with a thin (<3 mm) superficial component (16/23, 69%, p < .001). Localized IH with AU had a thick (>3 mm) superficial component (11/12, 92%, p < .001).All diaper area IH with AU (9/35) were segmental with thin superficial component (100%, p = .02). IH with AU in the head/neck (10/35) were more commonly localized (67%) and mixed (62.5%), while segmental, thick superficial morphology was more common on trunk (9/35) and upper extremities (7/35).ConclusionsIH resulting in AU differ in clinical features by anatomic site. Those in the diaper area are nearly always segmental with thin superficial component, whereas other sites tend to be localized, mixed, with thick superficial component. These distinct phenotypes may prove useful in the clinical setting for physicians to identify patterns of IH ulceration with increased risk of aggressive, persistent ulceration.
Clinical Features, Prognostic Factors, and Treatment Interventions for Ulceration in Patients With Infantile Hemangioma
Shah, Sonal D. , Witman, Patricia M., Harfmann, Katya , Bradley, Flora , Blei, Francine , Alsumait, Anwar, Gupta, Deepti , Covelli, Isabela, Streicher, Jenna L., Cotton, Colleen , Tollefson, Megha M. , Nguyen, Henry, Hunt, Raegan , Frieden, Ilona J. , Tollefson, Megha, Faith, Esteban Fernández , Pope, Elena , Moore‐Clingenpeel, Melissa
JAMA Dermatology | March 31, 2021 | Volume: 157 | Issue: 5 | Pages: 566
Successful Treatment of Keratosis Pilaris Rubra with Pulsed Dye Laser
Schoch, Jennifer J. , Tollefson, Megha M. , Witman, Patricia M., Davis, Dawn M. R., Davis, Dawn Marie R.
Pediatric Dermatology | June 10, 2016 | Volume: 33 | Issue: 4 | Pages: 443-446
AbstractBackgroundKeratosis pilaris rubra is a common but rarely reported condition characterized by follicular‐based hyperkeratotic papules on a background of erythema. It can be embarrassing and symptomatic for patients, particularly adolescent boys. We sought to explore the efficacy of pulsed dye laser (PDL) in the treatment of keratosis pilaris rubra.MethodsEight patients were treated with PDL for keratosis pilaris rubra.ResultsAll patients reported noticeable improvement after one to four treatments.ConclusionsPDL is an effective, easily accessible, and underused therapy in the treatment of keratosis pilaris rubra.