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Sim, Franklin H.

https://orcid.org/0000-0002-6623-5799

Mayo Clinic

Mayo Clinic

Citations 42

Xanthoma of Bone
Bertoni, Franco, Unni, K. Krishnan, McLeod, Richard A., Sim, Franklin H.

American Journal of Clinical Pathology | March 17, 2016 | Volume: 90 | Issue: 4 | Pages: 377-384

10.1093/ajcp/90.4.377 Get It

Ice Hockey Injuries
Sim, Franklin H. , Simonet, William T., Melton, L. Joseph, Lehn, Tracy A.

The American Journal of Sports Medicine | February 18, 2016 | Volume: 16 | Issue: 1_suppl | Pages: S-86-S-96

10.1177/03635465880160s119 Get It

Ice hockey is a team sport that has recently grown in popularity not only in the United States but also in Canada and Europe. With this increase in popularity has come a growing concern about the number and severity of injuries. The world literature on the biomechanics and physiology of ice hockey was reviewed in an attempt to evaluate the forces and mechanisms involved in the game. The influence of rule and equipment changes on injury patterns was particularly studied. Several studies on the epidemiology of injuries, providing data on the types of injuries and the mechanisms of those injuries, were analyzed to determine the conclusions that could be supported and those that require further study. Possible changes in the patterns and types of injury are outlined.
Late Complications and Long-Term Outcomes following Aseptic Revision of a Hip Arthroplasty Performed for Oncological Resection
Wagner, Eric R. , Wilke, Benjamin K. , Taunton, Michael J. , Sim, Franklin H. , Wyles, Cody C. , Houdek, Matthew T. , Wilke, B K , Wagner, Eric R , Taunton, Michael J

HIP International | October 2, 2015 | Volume: 25 | Issue: 5 | Pages: 428-434

10.5301/hipint.5000280 Get It

Purpose In order to achieve an oncological margin during limb salvage surgery for tumours around the hip, part or the entire hip joint is frequently sacrificed. Hip arthroplasty restores a functional extremity and achieves limb salvage. Currently there is a paucity of data concerning the late complications, long-term survival, and the risks of re-revision following aseptic revision of a total hip arthroplasty (THA) performed following an oncological resection. Methods We identified 78 patients who underwent aseptic revision of a THA which was performed for an oncological process involving the hip from 1972 to 2006. All patients had a minimum 5 years of follow-up with a mean of 13 years. Outcomes were compared to 1,378 patients undergoing aseptic revision of a THA that was performed for a diagnosis of osteoarthritis. Results The mean 5-, 10-, 15-, and 20-year re-revision-free survival for an oncologic process of the hip was 100%, 85%, 69%, and 57%. Within this cohort, younger patients were at an increased risk of revision surgery. There was no difference in survivorship of the revision implant at any of the aforementioned time points between the oncologic and osteoarthritis cohorts. Patients with an oncologic diagnosis had a higher rate of dislocations, component wear, and loosening compared to the osteoarthritis group. Conclusion Late complications following revision surgery of THA performed for an oncologic resection are common. The results of this study provide information for counselling patients on implant survivorship and complications following aseptic revision THA after index surgery for an oncologic indication.
Functional outcomes and quality of life following surgical treatment of aneurysmal bone cysts of the pelvis in children
Novais, Eduardo N. , Zimmerman, Amy K., Lewallen, Laura, Rose, Peter S. , Sim, Franklin H. , McIntosh, Amy L.

Journal of Children's Orthopaedics | May 10, 2014 | Volume: 8 | Issue: 3 | Pages: 281-288

10.1007/s11832-014-0588-x Get It

Background Aneurysmal bone cysts (ABCs) are a benign aggressive tumor that occurs rarely in the pelvis in the pediatric population. Pelvic ABCs may involve the triradiate cartilage and/or the acetabulum, which increases the technical difficulty of surgical treatment and has potential implications on the growth and development of the hip joint. This study examines the clinical presentation, rate of surgical complications, and recurrence rate, as well as, long-term clinical and functional outcomes of children with pelvic ABCs treated at a single institution by a single treatment modality. Methods Between 1988 and 2008, 142 children with histologically confirmed ABCs were treated at our institution. Seventeen (12 %) tumors were located in the pelvis. A total of 13 pelvic ABCs (5 ilium-periacetabular, 4 pubic, 3 ilium-iliac wing, and 1 ischium) were included in this study. There were eight male and five female patients with a mean age of 12.9 years (range 4.1–17.5 years) at the time of surgery. The Toronto Extremity Salvage Score (TESS), the Musculoskeletal Tumor Society 1993 (MSTS’93) score, and the Short Form Health Survey Sf-36 were obtained at a minimum 5-year follow-up in all patients (mean follow-up 11.5 years, range 5.5–19.8 years). The mean age at follow-up was 24.3 years (range 14.6–32.6 years). Results All patients were treated surgically with intralesional curettage extended with a high-speed burr and bone grafting. Eight patients received adjunctive therapy with phenol. Five patients had preoperative selective arterial embolization. Of the 13 patients, 1 had a local recurrence diagnosed at 6 months after surgery. The only complication in the cohort was a superficial wound infection. At the latest follow-up, all patients were free of disease. The mean TESS score was 95 and the mean MSTS’93 score was 93 %. The mean self-rated general health score, according to the SF-36 was 87 % of total points possible. Conclusions Extended curettage and bone grafting of pelvic ABCs in the pediatric population can yield high clinical and functional scores at an average of 11 years follow-up with a low rate of complications and recurrence. Level of evidence IV, case series.
Metastatic Tumors of the Foot and Ankle
Hattrup, Steven J. , Amadio, Peter C. , Sim, Franklin H. , Lombardi, Robert M.

Foot & Ankle | March 3, 2013 | Volume: 8 | Issue: 5 | Pages: 243-247

10.1177/107110078800800503 Get It

In a review of the Mayo Clinic files, 17 biopsy-proven cases of metastatic tumors of the foot and ankle were found; 4 additional cases were considered to have metastatic disease on the basis of clinical and radiographic evidence but no histological confirmation was available. Lung, kidney, and colon were the most common sites of the primary tumors. The patients survived as long as 28 months after discovery of the metastasis. Treatment consisted of individualized combinations of orthotics, surgery, and radiotherapy to maintain mobility. In 9 of these 17 cases, no primary lesion was identified at the time the metastasis was diagnosed. Metastatic tumors of the foot present special problems in diagnosis and management.
Effect of Granulocyte-Stimulating Factors on Marrow of Adult Patients with Musculoskeletal Malignancies: Incidence and MRI Findings
Hartman, Robert P. , Okuno, Scott H. , Sim, Franklin H. , Sundaram, Murali

American Journal of Roentgenology | February 28, 2013 | Volume: 183 | Issue: 3 | Pages: 645-653

10.2214/ajr.183.3.1830645 Get It

A Case of Q Fever Prosthetic Joint Infection and Description of an Assay for Detection of Coxiella burnetii
Tande, Aaron J. , Cunningham, Scott A. , Raoult, Didier , Sim, Franklin H. , Berbari, Elie F. , Patel, Robin , Tande, Aaron , Patel, Robin , Cunningham, Scott A

Journal of Clinical Microbiology | October 18, 2012 | Volume: 51 | Issue: 1 | Pages: 66-69

10.1128/jcm.02352-12 Get It

ABSTRACT We present the first published case of Coxiella burnetii prosthetic joint infection. Diagnosis was established with PCR and culture of periprosthetic tissue and synovial fluid (and serology). A novel PCR assay is described herein. Q fever should be considered in patients with prosthetic joint infection without an identified pathogen.
Multicentric Osteosarcoma
Corradi, Domenico , Wenger, Doris E. , Bertoni, Franco, Bacchini, Patrizia, Bosio, Silvia , Goldoni, Matteo , Unni, K. Krishnan, Sim, Franklin H. , Inwards, Carrie Y.

American Journal of Clinical Pathology | October 26, 2011 | Volume: 136 | Issue: 5 | Pages: 799-807

10.1309/ajcp0v0oatkcnazp Get It

Abstract Multicentric osteosarcoma (M-OGS) is characterized by multicentricity of osseous osteosarcomas, either synchronous or metachronous, without visceral involvement. The study’s purpose was to clinicopathologically and radiographically analyze 56 cases of M-OGS (22 synchronous and 34 metachronous). The distal femur was the most common site. Histologically, all tumors were high grade. Of 22 patients with synchronous M-OGS, 16 had 3 or more simultaneous tumors; the axial skeleton was involved in 14 (64%) of 22 cases. In metachronous M-OGS, the second malignancy occurred after a median of 22 months. Treatment was surgery, chemotherapy, radiotherapy, or a combination of these. Patients with metachronous osteosarcoma had a median survival longer than did patients with synchronous tumors. Overall, 8 long-term survivors were treated by aggressive surgery with wide margins (plus chemotherapy and/or radiotherapy). M-OGS combines multiple skeletal locations of high-grade conventional osteosarcomas and has a poor prognosis. Aggressive surgery may result in improved long-term survival, particularly in patients with metachronous disease.
Current Perspectives on Desmoid Tumors: The Mayo Clinic Approach
Joglekar, Siddharth, Rose, Peter S. , Sim, Franklin H. , Okuno, Scott H. , Petersen, Ivy A.

Cancers | August 9, 2011 | Volume: 3 | Issue: 3 | Pages: 3143-3155

10.3390/cancers3033143 Get It

Desmoid tumors are a rare group of locally aggressive, non malignant tumors of fibroblastic origin that can lead to significant morbidity due to local invasion. Despite advances in the understanding of these tumors, their natural history is incompletely understood and the optimal treatment is still a matter of debate. Local control is the main goal of treatment and there has been a change in philosophy regarding the management of these tumors from aggressive surgical resection to function preservation. A multidisciplinary approach is essential to plan local control with acceptable morbidity. The current Mayo Clinic algorithm for the treatment of these tumors is based on institutional experience and the available evidence in the literature: asymptomatic/non progressive lesions away from vital structures are managed with observation and regular imaging; primary or recurrent desmoid tumors which are symptomatic or progressive or near vital structures are managed with wide surgical resection when wide surgical margins are possible with minimal functional and cosmetic loss. When positive or close surgical margins are likely, surgical resection with adjuvant radiotherapy or definitive radiotherapy is preferred. If likely functional or cosmetic deficit is unacceptable, radiotherapy is the treatment of choice. Unresectable lesions are considered for radiotherapy, chemotherapy or newer modalities however an unresectable lesion associated with a painful, functionless, infected extremity is managed with an amputation.