Citations 3
Case for staged thyroidectomy
Ronen, Ohad , Robbins, K. Thomas , Olsen, Kerry D., Shaha, Ashok R. , Nixon, Iain J. , Zafereo, Mark , Hartl, Dana M. , Kowalski, Luiz Paulo , Rodrigo, Juan P. , Coca‐Pelaz, Andrés , Poorten, Vincent Vander , Sanabria, Álvaro , Rinaldo, Alessandra , Ferlito, Alfio , Kowalski, Luiz P , Rodrigo, Juan P , Coca-Pelaz, Andrés , Vander Poorten, Vincent , Sanabria, Alvaro , Randolph, Gregory William , Mäkitie, Antti , Angelos, Peter
Head & Neck | August 6, 2020 | Volume: 42 | Issue: 10 | Pages: 3061-3071
AbstractRecent modifications in the management of well‐differentiated thyroid cancer have resulted in significant alterations in clinical approach. Utilizing a series of preoperative and postoperative risk factors involving both the patient and the disease pathology, we offer the term “staged thyroidectomy” to help organize these risk factors for patients and the endocrine team to optimize management. This approach is intended to incorporate our latest nuanced understanding of certain endocrine pathology and may serve to optimize patient outcomes.
European Perspective on 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: Proceedings of an Interactive International Symposium
Luster, Markus , Aktolun, Cumali , Amendoeira, Isabel, Bible, Keith C. , Duntas, Leonidas H. , Handkiewicz-Junak, Daria , Hoffmann, Martha, Jarząb, Barbara , Musholt, Thomas J. , Newbold, Kate, Nixon, Iain J. , Sobrinho‐Simões, Manuel , Tuttle, R. Michael , Verburg, Frederik A. , Wartofsky, Leonard , Führer, Dagmar, Barczyński, Marcin , Elisei, Rossella , Leenhardt, Laurence , Smit, Johannes W. A. , Sosa, Julie Ann
Thyroid | November 28, 2018 | Volume: 29 | Issue: 1 | Pages: 7-26
Prognostic Value of Vascular Invasion in Well-Differentiated Papillary Thyroid Carcinoma
Wreesmann, Volkert B. , Nixon, Iain J. , Rivera, Michael , Katabi, Nora , Palmer, Frank L., Ganly, Ian , Shaha, Ashok R. , Tuttle, R. Michael , Shah, Jatin P. , Patel, Snehal G. , Ghossein, Ronald
Thyroid® | March 6, 2015 | Volume: 25 | Issue: 5 | Pages: 503-508
Background: Vascular invasion (VI) is an important predictor of distant metastasis and possible radioactive iodine (RAI) benefit in follicular, Hürthle cell, and poorly differentiated thyroid carcinomas, but its role in well-differentiated papillary thyroid cancer (WDTC) remains unclear. Methods: Archived pathological material of all differentiated thyroid carcinoma patients undergoing primary surgical treatment at Memorial Sloan-Kettering Cancer Center between 1986 and 2003 was reviewed by two dedicated thyroid pathologists. Only WDTCs were included in the present study. Standard statistical methods were used to assess the relationship between VI and outcomes of interest, including 10-year disease-specific survival (DSS), regional recurrence-free survival (RRFS), and distant recurrence-free survival (DRFS). Results: VI was present in 47 of 698 WDTC (6.7%). VI was significantly associated with tumor size >4.0 cm, extrathyroidal extension, distant metastasis, and RAI treatment. On univariate analysis, VI was predictive of decreased 10-year DRFS, but not DSS or RRFS. On multivariate analysis, VI was not an independent predictor of DRFS. Univariate survival analysis of 422 RAI-naïve WDTC showed that both size >4 cm and VI were predictors of outcome, but only size remained independently predictive on multivariate analysis. Conclusion: The presence of VI is not an independent predictor of outcome in WDTC.