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Alexander, Gene E.

https://orcid.org/0000-0002-6476-5606

Mayo Clinic

University of Arizona

Citations 26

IC‐P2‐111: Regional hypometabolism in cognitively normal Hispanic carriers of the apolipoprotein E ϵ4 allele
Reiman, Eric M. , Alexander, Gene E. , Bandy, Daniel, Smilovici, Oded, Lee, Wendy , Recshke, Cole, Caselli, Richard J. , Langbaum, Jessica B. S. , Chen, Kewei , Recshke, Cole

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_2 | Pages: No page available

10.1016/j.jalz.2008.05.2566 Get It

IC‐03‐06: Six month MRI gray matter declines in Alzheimer's dementia evaluated by voxel‐based morphometry with multivariate network analysis: Preliminary findings from the ADNI study
Alexander, Gene E. , Hanson, Krista D., Reiman, Eric M. , Kornak, John , Schuff, Norbert, Weiner, Michael W. , Chen, Kewei , Bernstein, Matt A. , Fox, Nick C. , Thompson, Paul M. , Jack, Clifford R.

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2008.05.011 Get It

P1‐311: Use of the support vector machine and sensitivity of an Alzheimer's disease‐related region‐of‐interest gray matter classifier in identifying amnestic mild cognitive impairment subjects who convert to Alzheimer's disease: Preliminary findings from t
Zhang, Hang , Bae, Min-Hyeok, Reiman, Eric M. , Alexander, Gene E. , Wu, Tong , Bae, Min Hyeok, Thompson, Paul M. , Jack, Clifford R. , Chen, Kewei

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_9 | Pages: No page available

10.1016/j.jalz.2008.05.902 Get It

P1‐259: Regional hypometabolism in cognitively normal Hispanic carriers of the apolipoprotein E–ϵ4 allele
Reiman, Eric M. , Alexander, Gene E. , Bandy, Daniel, Smilovici, Oded, Lee, Wendy , Recshke, Cole, Caselli, Richard J. , Langbaum, Jessica B. S. , Chen, Kewei , Recshke, Cole

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_9 | Pages: No page available

10.1016/j.jalz.2008.05.849 Get It

P1‐216: Six month MRI gray matter declines in Alzheimer's dementia evaluated by voxel‐based morphometry with multivariate network analysis: Preliminary findings from the Alzheimer's Disease Neuroimaging Initiative
Alexander, Gene E. , Hanson, Krista D., Reiman, Eric M. , Kornak, John , Schuff, Norbert, Weiner, Michael W. , Chen, Kewei , Bernstein, Matt A. , Fox, Nick C. , Thompson, Paul M. , Jack, Clifford R.

Alzheimer's & Dementia | July 24, 2008 | Volume: 4 | Issue: 4S_Part_8 | Pages: No page available

10.1016/j.jalz.2008.05.805 Get It

P‐020: Regional gray matter reductions in Alzheimer's dementia and amnestic mild cognitive impairment: Preliminary findings from the Alzheimer's disease neuroimaging initiative using voxel‐based morphometry
Alexander, Gene E. , Reiman, Eric M. , Aschenbrenner, Melaney, Hanson, Krista D., Kornak, John , Schuff, Norbert, Weiner, Michael W. , Chen, Kewei , Merkley, Tricia L. , Dale, Anders M. , Bernstein, Matt A. , Fox, Nick C. , Thompson, Paul M. , Jack, Clifford R.

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_1 | Pages: No page available

10.1016/j.jalz.2007.04.236 Get It

O1–05–03: PET measurements of posterior cingulate glucose metabolism are superior to MRI measurements of hippocampal volume in distinguishing cognitively normal persons at differential genetic risk for Alzheimer's disease
Reiman, Eric M. , Alexander, Gene E. , Reschke, Cole, Lee, Wendy , Smilovici, Oded, Buckley, Shannon, Sacrey, Diana Truran, Schuff, Norbert, Müller, Stig , Weiner, Michael W. , Caselli, Richard J., Chen, Kewei , Smilovici, Oded

Alzheimer's & Dementia | June 4, 2007 | Volume: 3 | Issue: 3S_Part_3 | Pages: No page available

10.1016/j.jalz.2007.04.070 Get It

Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
Liang, Winnie S. , Dunckley, Travis , Beach, Thomas G. , Grover, Andrew, Mastroeni, Diego , Walker, Douglas G. , Caselli, Richard J. , Kukull, Walter A. , McKeel, Daniel W., Morris, John C. , Hulette, Christine, Schmechel, Donald E., Alexander, Gene E. , Reiman, Eric M. , Rogers, Joseph, Stephan, Dietrich A. , Morris, John C

Physiological Genomics | October 31, 2006 | Volume: 28 | Issue: 3 | Pages: 311-322

10.1152/physiolgenomics.00208.2006 Get It

In this article, we have characterized and compared gene expression profiles from laser capture microdissected neurons in six functionally and anatomically distinct regions from clinically and histopathologically normal aged human brains. These regions, which are also known to be differentially vulnerable to the histopathological and metabolic features of Alzheimer’s disease (AD), include the entorhinal cortex and hippocampus (limbic and paralimbic areas vulnerable to early neurofibrillary tangle pathology in AD), posterior cingulate cortex (a paralimbic area vulnerable to early metabolic abnormalities in AD), temporal and prefrontal cortex (unimodal and heteromodal sensory association areas vulnerable to early neuritic plaque pathology in AD), and primary visual cortex (a primary sensory area relatively spared in early AD). These neuronal profiles will provide valuable reference information for future studies of the brain, in normal aging, AD and other neurological and psychiatric disorders.
IC–P–045: Using partial–least squares to demonstrate a correlation between combined PET/MRI scores and apolipoprotein E ϵ4 gene dose
Reiman, Eric M. , Alexander, Gene E. , Caselli, Richard J., Bandy, Dan, Chen, Kewei

Alzheimer's & Dementia | August 17, 2006 | Volume: 2 | Issue: 3S_Part_22 | Pages: No page available

10.1016/j.jalz.2006.05.2250 Get It

IC–P–025: Regional network pattern of MRI gray matter volume in Alzheimer's dementia
Alexander, Gene E. , Aschenbrenner, Melaney, Reiman, Eric M. , Caselli, Richard J., Rapoport, Stanley I., Moeller, James R., Chen, Kewei , Merkley, Tricia L. , Lewis, Diana J. , Pietrini, Pietro , Teipel, Stefan Johannes , Hampel, Harald

Alzheimer's & Dementia | August 17, 2006 | Volume: 2 | Issue: 3S_Part_21 | Pages: No page available

10.1016/j.jalz.2006.05.2230 Get It