Leith, Catherine P.
https://orcid.org/0000-0003-3645-0292
Mayo Clinic
University of Wisconsin–Madison
Citations 1
TPL2 kinase regulates the inflammatory milieu of the myeloma niche
Hope, Chelsea, Ollar, Samuel J., Héninger, Erika , Hebron, Ellen, Jensen, Jeffrey L. , Kim, Jaehyup , Μαρουλάκου, Ιωάννα, Leith, Catherine P. , Yang, David T. , Hematti, Peiman , Chesi, Marta , Bergsagel, P. Leif , Asimakopoulos, Fotis , Bergsagel, P. Leif , Miyamoto, Shigeki , Callander, Natalie S. , Hematti, Peiman
Blood | April 11, 2014 | Volume: 123 | Issue: 21 | Pages: 3305-3315
Key PointsWe describe a novel, druggable pathway that controls myeloma growth through macrophages in the myeloma microenvironment. Macrophages are dominant orchestrators of the inflammatory milieu of the myeloma niche.