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Ford, Aubri

Mayo Clinic

Baylor College of Medicine

Citations 1

Compromised pressure-generating capacity of diaphragmatic muscle and its interaction with the lower rib cage at high lung volume during airway occlusion
Boriek, Aladin M. , Rodriguez-Santiago, Noralis, Kim, Sanghyun , Wynd, Shari , Hubmayr, Rolf D., Kim, Sanghyun , Ford, Aubri

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | October 24, 2025 | Volume: 329 | Issue: 6 | Pages: R959-R971

10.1152/ajpregu.00080.2025 Get It

Data from the current study support the hypothesis that the pressure-generating capacity of the diaphragm at high lung volume is compromised primarily due to a mechanism that involves a combined mechanical effect of hyperinflation and substantial muscle contraction rather than a significant loss of its muscle fiber curvature.