Citations 1
Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease
Afrin, Humayra , Robichaud, Jielu Hao, Harris, Peter C. , Gupta, Navin , Gupta, Navin , Harris, Peter C , Robichaud, Jielu Hao, Qamar, Usama
American Journal of Physiology-Renal Physiology | July 2, 2025 | Volume: 329 | Issue: 2 | Pages: F257-F268
Stem cell-derived kidney organoids enable human genetic disease modeling to identify the parathyroid hormone 1 receptor as a potential new therapeutic target for developmental polycystic kidney disease.