Citations 1
The impact of multimorbidity on Quality of Life in inflammatory myopathies: A cluster analysis from the COVAD dataset
Fornaro, Marco , Venerito, Vincenzo , Pellico, Maria Rosa , Iannone, Florenzo , Joshi, Mrudula , Chen, Yi‐Ming , Tan, Ai Lyn , Saha, Sreoshy , Chatterjee, Tulika , Agarwal, Vishwesh , Kadam, Esha , Hasan, A T M Tanveer , Shumnalieva, Russka , Milchert, Marcin , Tan, Chou Luan , Vaidya, Binit , Kuwana, Masataka , Shaharir, Syahrul Sazliyana , Tehozol, Erick Adrian Zamora , Gutiérrez, Carlos Enrique Toro , Goo, Phonpen Akawatcharangura , Katchamart, Wanruchada , Parodis, Ioannis , Nikiphorou, Elena , Chinoy, Hector , Agarwal, Vikas , Gupta, Latika, Group, CoVAD Study, Sen, Parikshit, Javaid, Mahnoor, Andreoli, Laura, Lini, Daniele, Schreiber, Karen, Nune, Arvind, Tan, Ai Lyn, Patel, Aarat, Pauling, John D, Wincup, Chris, Barman, Bhupen, Torre, Ignacio García-De La, Colunga-Pedraza, Iris J, Merayo-Chalico, Javier, Chibuzo, Okwara Celestine, Kibbi, Lina El, Lilleker, James B, Salim, Babur, Gheita, Tamer, Saavedra, Miguel A, Griger, Zoltán, Kardes, Sinan, Vince, Melinda Nagy, Singh, Yogesh Preet, Ranjan, Rajiv, Jain, Avinash, Pandya, Sapan C, Pilania, Rakesh Kumar, Sharma, Aman, M, Manesh Manoj, Gupta, Vikas, Kavadichanda, Chengappa G, Patro, Pradeepta Sekhar, Ajmani, Sajal, Phatak, Sanat, Goswami, Rudra Prosad, Chowdhury, Abhra Chandra, Mathew, Ashish Jacob, Shenoy, Padnamabha, Asranna, Ajay, Bommakanti, Keerthi Talari, Shukla, Anuj, Pande, Arunkumar R, Chandwar, Kunal, Ghodke, Akanksha, Boro, Hiya, Fazal, Zoha Zahid, Vaidya, Binit, Cansu, Döndü Üsküdar, Yıldırım, Reşit, Gasparyan, Armen Yuri, Papa, Nicoletta Del, Sambataro, Gianluca, Fabiola, Atzeni, Govoni, Marcello, Parisi, Simone, Bocci, Elena Bartoloni, Sebastiani, Gian Domenico, Fusaro, Enrico, Sebastiani, Marco, Quartuccio, Luca, Franceschini, Franco, Sainaghi, Pier Paolo, Orsolini, Giovanni, Angelis, Rossella De, Danieli, Maria Giovanna, Grignaschi, Silvia, Giollo, Alessandro, Alunno, Alessia, Traboco, Lisa S, Wibowo, Suryo Anggoro Kusumo, Loarce-Martos, Jesús, Prieto-González, Sergio, Gonzalez, Raquel Aranega, Yoshida, Akira, Nakashima, Ran, Sato, Shinji, Kimura, Naoki, Kaneko, Yuko, Gono, Takahisa, Tomaras, Stylianos, Proft, Fabian Nikolai, Holzer, Marie-Therese, Gromova, Margarita Aleksandrovna, Aharonov, Or, Griger, Zoltán, Hmamouchi, Ihsane, bouchti, Imane El, Baba, Zineb, Giannini, Margherita, Maurier, François, Campagne, Julien, Meyer, Alain, Langguth, Daman, Limaye, Vidya, Needham, Merrilee, Srivastav, Nilesh, Hudson, Marie, Landon-Cardinal, Océane, Zuleta, Wilmer Gerardo Rojas, Arbeláez, Álvaro, Cajas, Javier, Silva, José António Pereira, Fonseca, João Eurico, Zimba, Olena, Ima-Edomwonyi, Uyi, Dedeke, Ibukunoluwa, Airenakho, Emorinken, Madu, Nwankwo Henry, Yerima, Abubakar, Olaosebikan, Hakeem, Becky, A, Koussougbo, Oruma Devi, Palalane, Elisa, So, Ho, Ugarte-Gil, Manuel Francisco, Chinchay, Lyn, Bernaola, José Proaño, Pimentel, Victorio, Fathi, Hanan Mohammed, Mohammed, Reem Hamdy A, Harifi, Ghita, Fuentes-Silva, Yurilís, Cabriza, Karoll, Losanto, Jonathan, Colaman, Nelly, Cachafeiro-Vilar, Antonio, Bautista, Generoso Guerra, Ho, Enrique Julio Giraldo, González, Raúl, Nunez, Lilith Stange, M, Cristian Vergara, Báez, Jossiell Then, Alonzo, Hugo, Pastelin, Carlos Benito Santiago, Salinas, Rodrigo García, Obiols, Alejandro Quiñónez, Chávez, Nilmo, Ordóñez, Andrea Bran, Argueta, Sandra, Llerena, Gil Alberto Reyes, Sierra-Zorita, Radames, Arrieta, Dina, Hidalgo, Eduardo Romero, Saenz, Ricardo, M, Idania Escalante, Morales, Roberto, Calapaqui, Wendy, Quezada, Ivonne, Arredondo, Gabriela, Pauling, John D , Wincup, Chris , Sambataro, Gianluca , Angelis, Rossella De , Loarce‐Martos, Jesus , Lini, Daniele , Fuentes-Silva, Yurilís , Giollo, Alessandro , Grignaschi, Silvia , Schreiber, Karen , Danieli, Maria Giovanna , Gupta, Latika , Shinjo, Samuel Katsuyuki , Hoff, Leonardo Santos , Kadam, Esha , Ziade, Nelly , Velikova, Tsvetelina , Hasan, A T M Tanveer , Shumnalieva, Russka , Milchert, Marcin , Tan, Chou Luan , Gracia-Ramos, Abraham Edgar , Cavagna, Lorenzo , Vaidya, Binit , Kuwana, Masataka , Sazliyana Shaharir, Syahrul , Knitza, Johannes , Makol, Ashima , Zamora Tehozol, Erick Adrian , Rojas Serrano, Jorge , Halabi, Hussein , Dey, Dzifa , Gutiérrez, Carlos Enrique Toro , Distler, Oliver , Katchamart, Wanruchada , Day, Jessica , Parodis, Ioannis , Nikiphorou, Elena , Chinoy, Hector , Agarwal, Vikas , Gupta, Latika , Joshi, Mrudula , Agarwal, Vishwesh , Tan, Ai Lyn , Chatterjee, Tulika , Pauling, John D , Wincup, Chris , Chen, Yi-Ming , Saha, Sreoshy , De Angelis, Rossella , Iannone, Florenzo , Shinjo, Samuel Katsuyuki , Ziadé, Nelly , Velikova, Tsvetelina , Gracia‐Ramos, Abraham Edgar , Makol, Ashima , Halabi, Hussein , Dey, Dzifa , Caballero‐Uribe, Carlo V. , Distler, Oliver , Day, Jessica , Group, CoVAD Study, Sen, Parikshit, Javaid, Mahnoor, Andreoli, Laura, Nune, Arvind, Tan, Ai Lyn, Patel, Aarat, Barman, Bhupen, Torre, Ignacio García-De La, Colunga-Pedraza, Iris J, Merayo-Chalico, Javier, Chibuzo, Okwara Celestine, Kibbi, Lina El, Lilleker, James B, Salim, Babur, Gheita, Tamer, Saavedra, Miguel A, Griger, Zoltán, Kardes, Sinan, Vince, Melinda Nagy, Singh, Yogesh Preet, Ranjan, Rajiv, Jain, Avinash, Pandya, Sapan C, Pilania, Rakesh Kumar, Sharma, Aman, M, Manesh Manoj, Gupta, Vikas, Kavadichanda, Chengappa G, Patro, Pradeepta Sekhar, Ajmani, Sajal, Phatak, Sanat, Goswami, Rudra Prosad, Chowdhury, Abhra Chandra, Mathew, Ashish Jacob, Shenoy, Padnamabha, Asranna, Ajay, Bommakanti, Keerthi Talari, Shukla, Anuj, Pande, Arunkumar R, Chandwar, Kunal, Ghodke, Akanksha, Boro, Hiya, Fazal, Zoha Zahid, Vaidya, Binit, Cansu, Döndü Üsküdar, Yıldırım, Reşit, Gasparyan, Armen Yuri, Papa, Nicoletta Del, Fabiola, Atzeni, Govoni, Marcello, Parisi, Simone, Bocci, Elena Bartoloni, Sebastiani, Gian Domenico, Fusaro, Enrico, Sebastiani, Marco, Quartuccio, Luca, Franceschini, Franco, Sainaghi, Pier Paolo, Orsolini, Giovanni, Alunno, Alessia, Traboco, Lisa S, Wibowo, Suryo Anggoro Kusumo, Prieto-González, Sergio, Gonzalez, Raquel Aranega, Yoshida, Akira, Nakashima, Ran, Sato, Shinji, Kimura, Naoki, Kaneko, Yuko, Gono, Takahisa, Tomaras, Stylianos, Proft, Fabian Nikolai, Holzer, Marie-Therese, Gromova, Margarita Aleksandrovna, Aharonov, Or, Griger, Zoltán, Hmamouchi, Ihsane, bouchti, Imane El, Baba, Zineb, Giannini, Margherita, Maurier, F. , Campagne, Julien, Meyer, Alain , Langguth, Daman, Limaye, Vidya, Needham, Merrilee, Srivastav, Nilesh, Hudson, Marie, Landon‐Cardinal, Océane , Zuleta, Wilmer Gerardo Rojas, Arbeláez, Álvaro, Cajas, Javier, Silva, José António Pereira, Fonseca, João Eurico, Zimba, Olena, Ima-Edomwonyi, Uyi, Dedeke, Ibukunoluwa, Airenakho, Emorinken, Madu, Nwankwo Henry, Yerima, Abubakar, Olaosebikan, Hakeem, Becky, A, Koussougbo, Oruma Devi, Palalane, Elisa, So, Ho, Ugarte-Gil, Manuel Francisco, Chinchay, Lyn, Bernaola, José Proaño, Pimentel, Victorio, Fathi, Hanan Mohammed, Mohammed, Reem Hamdy A, Harifi, Ghita, Cabriza, Karoll, Losanto, Jonathan, Colaman, Nelly, Cachafeiro-Vilar, Antonio, Bautista, Generoso Guerra, Ho, Enrique Julio Giraldo, González, Raúl, Nunez, Lilith Stange, M, Cristian Vergara, Báez, Jossiell Then, Alonzo, Hugo, Pastelin, Carlos Benito Santiago, Salinas, Rodrigo García, Obiols, Alejandro Quiñónez, Chávez, Nilmo, Ordóñez, Andrea Bran, Argueta, Sandra, Llerena, Gil Alberto Reyes, Sierra-Zorita, Radames, Arrieta, Dina, Hidalgo, Eduardo Romero, Saenz, Ricardo, M, Idania Escalante, Morales, Roberto, Calapaqui, Wendy, Quezada, Ivonne, Arredondo, Gabriela
Rheumatology | September 26, 2024 | Volume: 64 | Issue: 4 | Pages: 2133-2142
Abstract Objective The presence of comorbidities can substantially affect patients’ quality of life, but data regarding their impact on idiopathic inflammatory myopathies (IIMs) are limited. Methods We examined the prevalence of comorbidities in IIM patients, other autoimmune rheumatic diseases (oAIRDs) and healthy controls (HCs), using data from the self-reported COVAD-2 survey. We defined basic multimorbidity (BM) as the presence of ≥2 non-rheumatic chronic conditions and complex multimorbidity (CM) as the presence of ≥3 non-rheumatic chronic conditions affecting ≥3 organ systems. Hierarchical clustering on principal components was performed for grouping. Results Among the COVAD respondents, 1558 IIMs, 4591 oAIRDs and 3652 HCs were analysed. IIMs exhibited a high burden of comorbidities (odds ratio [OR]: 1.62 vs oAIRDs and 2.95 vs HCs, P < 0.01), BM (OR: 1.66 vs oAIRDs and 3.52 vs HCs, P < 0.01), CM (OR: 1.69 vs AIRDs and 6.23 vs HCs, P < 0.01) and mental health disorders (MHDs) (OR: 1.33 vs oAIRDs and 2.63 vs HCs, P < 0.01). Among the IIM patients, those with comorbidities or MHDs had lower PROMIS Global Physical (PGP), PROMIS Global Mental (PGM), and PROMIS Physical Function (SF10) scores, and higher fatigue (F4a) scores (all P < 0.001). PGP, PGM, SF10a and F4a were influenced by age, active disease, BM and MHDs. Four distinct clusters were identified among the IIMs according to comorbidities and PROMIS scores. Conclusion Patients with IIMs have a higher burden of comorbidities that influence physical and mental health, identifiable as clinical clusters for optimized and holistic management approaches.