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Ishii, Lisa E.

https://orcid.org/0000-0001-5287-2597

Mayo Clinic

Johns Hopkins University

Citations 8

Eye-Tracking in Facial Plastic Surgery: A Guide to Study Design
Dey, Jacob K. , Xu, Mengyuan, Dey, Jacob K , Xu, Mengyuan, Ishii, Lisa E. , Ishii, Masaru

Facial Plastic Surgery & Aesthetic Medicine | September 11, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/26893614261487071 Get It

Eye-tracking provides an objective measure of how observers direct visual attention to presented stimuli and has become an increasingly valuable tool in facial plastic surgery. It offers unique insight into how facial conditions and surgical interventions impact facial attention. A well-designed eye-tracking study can address patient questions about how others look at their face, identify targets for visual improvement, and objectively assess facial plastic surgery outcomes. Significant variability exists in eye-tracking study design and execution within facial plastic surgery, often producing data that are erroneous, difficult to interpret, or not generalizable to clinical practice. There are currently no guidelines for the design of eye-tracking studies in facial plastic surgery. Furthermore, the technical requirements for facial eye-tracking studies differ from those for non-facial studies. This article aims to synthesize the existing literature and authors’ experience to establish basic guidelines for designing eye-tracking studies in facial plastic surgery. We hope this guide will help investigators design high-quality eye-tracking studies to drive meaningful advances in the field of facial plastic surgery.
Response to Kantor re: “Measuring Outcomes of Mohs Defect Reconstruction Using Eye-Tracking Technology” ( Facial Plast Surg Aesthet Med. 2020;22(2):122)
Ishii, Lisa E. , Ishii, Masaru , Dey, Jacob K.

Facial Plastic Surgery & Aesthetic Medicine | March 4, 2020 | Volume: 22 | Issue: 2 | Pages: 123-123

10.1089/fpsam.2020.29020.jkd Get It

Measuring Outcomes of Mohs Defect Reconstruction Using Eye-Tracking Technology
Dey, Jacob K. , Ishii, Lisa E. , Boahene, Kofi , Byrne, Patrick J., Ishii, Masaru , Dey, Jacob K

JAMA Facial Plastic Surgery | October 31, 2019 | Volume: 21 | Issue: 6 | Pages: 518-525

10.1001/jamafacial.2019.1072 Get It

Importance Objectively measuring how Mohs defect reconstruction changes casual observer attention has important implications for patients and facial plastic surgeons. Objective To use eye-tracking technology to objectively measure the ability of Mohs facial defect reconstruction to normalize facial attention. Design, Setting, and Participants This observational outcomes study was conducted at an academic tertiary referral center from January to June 2016. An eye-tracking system was used to record how 82 casual observers directed attention to photographs of 32 patients with Mohs facial defects of varying sizes and locations before and after reconstruction as well as 16 control faces with no facial defects. Statistical analysis was performed from November 2018 to January 2019. Main Outcomes and Measures First, the attentional distraction caused by facial defects was quantified in milliseconds of gaze time using eye tracking. Second, the eye-tracking data were analyzed using mixed-effects linear regression to assess the association of facial defect reconstruction with normalized facial attention. Results The 82 casual observers (63 women and 19 men; mean [SD] age, 34 [12] years) viewed control faces in a similar and consistent fashion, with most attention (65%; 95% CI, 62%-69%) directed at the central triangle, which includes the eyes, nose, and mouth. The eyes were the most visually important feature, capturing a mean of 60% (95% CI, 57%-64%) of fixation time within the central triangle and 39% (95% CI, 36%-43%) of total observer attention. The presence of Mohs defects was associated with statistically significant alterations in this pattern of normal facial attention. The larger the defect and the more centrally a defect was located, the more attentional distraction was observed, as measured by increased attention on the defect and decreased attention on the eyes, ranging from 729 (95% CI, 526-931) milliseconds for small peripheral defects to 3693 (95% CI, 3490-3896) milliseconds for large central defects. Reconstructive surgery was associated with improved gaze deviations for all faces and with normalized attention directed to the eyes for all faces except for those with large central defects. Conclusions and Relevance Mohs defects are associated with altered facial perception, diverting attention from valuable features such as the eyes. Reconstructive surgery was associated with normalized attentional distraction for many patients with cutaneous Mohs defects. These data are important to patients who want to know how reconstructive surgery could change the way people look at their face. The data also point to the possibility of outcomes prediction based on facial defect size and location before reconstruction. Eye tracking is a valuable research tool for outcomes assessment that lays the foundation for understanding how reconstructive surgery may change perception and normalize facial deformity.
Societal Identification of Facial Paralysis and Paralysis Location
Su, Peiyi , Ishii, Lisa E. , Nellis, Jason C. , Dey, Jacob K. , Bater, Kristin L., Byrne, Patrick J., Boahene, Kofi , Ishii, Masaru , Dey, Jacob, Dey, Jacob K

JAMA Facial Plastic Surgery | February 8, 2018 | Volume: 20 | Issue: 4 | Pages: 272-276

10.1001/jamafacial.2017.2402 Get It

Clinical Practice Guideline: Improving Nasal Form and Function after Rhinoplasty
Ishii, Lisa E. , Basura, Gregory J. , Abramson, Peter J., Chaiet, Scott R. , Davis, Kara S., Doghramji, Karl , Farrior, Edward H., Finestone, Sandra A., Murphy, Robert X., Park, John G. , Setzen, Michael, Strike, Deborah J., Walsh, Sandra A. , Warner, Jeremy P., Nnacheta, Lorraine C., Meister, Kara D. , Tollefson, Travis T. , Rosenfeld, Richard M. , Ishman, Stacey L. , Meister, Kara D

Otolaryngology–Head and Neck Surgery | February 1, 2017 | Volume: 156 | Issue: S2 | Pages: No page available

10.1177/0194599816683153 Get It

ObjectiveRhinoplasty, a surgical procedure that alters the shape or appearance of the nose while preserving or enhancing the nasal airway, ranks among the most commonly performed cosmetic procedures in the United States, with >200,000 procedures reported in 2014. While it is difficult to calculate the exact economic burden incurred by rhinoplasty patients following surgery with or without complications, the average rhinoplasty procedure typically exceeds $4000. The costs incurred due to complications, infections, or revision surgery may include the cost of long‐term antibiotics, hospitalization, or lost revenue from hours/days of missed work.The resultant psychological impact of rhinoplasty can also be significant. Furthermore, the health care burden from psychological pressures of nasal deformities/aesthetic shortcomings, surgical infections, surgical pain, side effects from antibiotics, and nasal packing materials must also be considered for these patients. Prior to this guideline, limited literature existed on standard care considerations for pre‐ and postsurgical management and for standard surgical practice to ensure optimal outcomes for patients undergoing rhinoplasty. The impetus for this guideline is to utilize current evidence‐based medicine practices and data to build unanimity regarding the peri‐ and postoperative strategies to maximize patient safety and to optimize surgical results for patients.PurposeThe primary purpose of this guideline is to provide evidence‐based recommendations for clinicians who either perform rhinoplasty or are involved in the care of a rhinoplasty candidate, as well as to optimize patient care, promote effective diagnosis and therapy, and reduce harmful or unnecessary variations in care. The target audience is any clinician or individual, in any setting, involved in the management of these patients. The target patient population is all patients aged ≥15 years. The guideline is intended to focus on knowledge gaps, practice variations, and clinical concerns associated with this surgical procedure; it is not intended to be a comprehensive reference for improving nasal form and function after rhinoplasty. Recommendations in this guideline concerning education and counseling to the patient are also intended to include the caregiver if the patient is <18 years of age.Action StatementsThe Guideline Development Group made the following recommendations: (1) Clinicians should ask all patients seeking rhinoplasty about their motivations for surgery and their expectations for outcomes, should provide feedback on whether those expectations are a realistic goal of surgery, and should document this discussion in the medical record. (2) Clinicians should assess rhinoplasty candidates for comorbid conditions that could modify or contraindicate surgery, including obstructive sleep apnea, body dysmorphic disorder, bleeding disorders, or chronic use of topical vasoconstrictive intranasal drugs. (3) The surgeon, or the surgeon’s designee, should evaluate the rhinoplasty candidate for nasal airway obstruction during the preoperative assessment. (4) The surgeon, or the surgeon’s designee, should educate rhinoplasty candidates regarding what to expect after surgery, how surgery might affect the ability to breathe through the nose, potential complications of surgery, and the possible need for future nasal surgery. (5) The clinician, or the clinician’s designee, should counsel rhinoplasty candidates with documented obstructive sleep apnea about the impact of surgery on nasal airway obstruction and how obstructive sleep apnea might affect perioperative management. (6) The surgeon, or the surgeon’s designee, should educate rhinoplasty patients before surgery about strategies to manage discomfort after surgery. (7) Clinicians should document patients’ satisfaction with their nasal appearance and with their nasal function at a minimum of 12 months after rhinoplasty.The Guideline Development Group made recommendations against certain actions: (1) When a surgeon, or the surgeon’s designee, chooses to administer perioperative antibiotics for rhinoplasty, he or she should not routinely prescribe antibiotic therapy for a duration >24 hours after surgery. (2) Surgeons should not routinely place packing in the nasal cavity of rhinoplasty patients (with or without septoplasty) at the conclusion of surgery.The panel group made the following statement an option: (1) The surgeon, or the surgeon’s designee, may administer perioperative systemic steroids to the rhinoplasty patient.
Clinical Practice Guideline: Improving Nasal Form and Function after Rhinoplasty Executive Summary
Ishii, Lisa E. , Basura, Gregory J. , Abramson, Peter J., Chaiet, Scott R. , Davis, Kara S., Doghramji, Karl , Farrior, Edward H., Finestone, Sandra A., Murphy, Robert X., Park, John G. , Setzen, Michael, Strike, Deborah J., Walsh, Sandra A. , Warner, Jeremy P., Nnacheta, Lorraine C., Meister, Kara D. , Tollefson, Travis T. , Rosenfeld, Richard M. , Ishman, Stacey L. , Meister, Kara D

Otolaryngology–Head and Neck Surgery | February 1, 2017 | Volume: 156 | Issue: 2 | Pages: 205-219

10.1177/0194599816683156 Get It

ObjectiveRhinoplasty, a surgical procedure that alters the shape or appearance of the nose while preserving or enhancing the nasal airway, ranks among the most commonly performed cosmetic procedures in the United States, with >200,000 procedures reported in 2014. While it is difficult to calculate the exact economic burden incurred by rhinoplasty patients following surgery with or without complications, the average rhinoplasty procedure typically exceeds $4000. The costs incurred due to complications, infections, or revision surgery may include the cost of long‐term antibiotics, hospitalization, or lost revenue from hours/days of missed work.The resultant psychological impact of rhinoplasty can also be significant. Furthermore, the health care burden from psychological pressures of nasal deformities/aesthetic shortcomings, surgical infections, surgical pain, side effects from antibiotics, and nasal packing materials must also be considered for these patients. Prior to this guideline, limited literature existed on standard care considerations for pre‐ and postsurgical management and for standard surgical practice to ensure optimal outcomes for patients undergoing rhinoplasty. The impetus for this guideline is to utilize current evidence‐based medicine practices and data to build unanimity regarding the peri‐ and postoperative strategies to maximize patient safety and to optimize surgical results for patients.PurposeThe primary purpose of this guideline executive summary is to provide evidence‐based recommendations for clinicians who either perform rhinoplasty or are involved in the care of a rhinoplasty candidate, as well as to optimize patient care, promote effective diagnosis and therapy, and reduce harmful or unnecessary variations in care. The target audience is any clinician or individual, in any setting, involved in the management of these patients. The target patient population is all patients aged ≥15 years. The guideline is intended to focus on knowledge gaps, practice variations, and clinical concerns associated with this surgical procedure; it is not intended to be a comprehensive reference for improving nasal form and function after rhinoplasty. Recommendations in this guideline concerning education and counseling to the patient are intended to include the caregiver if the patient is <18 years of age.Action StatementsThe Guideline Development Group made the following recommendations: (1) Clinicians should ask all patients seeking rhinoplasty about their motivations for surgery and their expectations for outcomes, should provide feedback on whether those expectations are a realistic goal of surgery, and should document this discussion in the medical record. (2) Clinicians should assess rhinoplasty candidates for comorbid conditions that could modify or contraindicate surgery, including obstructive sleep apnea, body dysmorphic disorder, bleeding disorders, or chronic use of topical vasoconstrictive intranasal drugs. (3) The surgeon, or the surgeon’s designee, should evaluate the rhinoplasty candidate for nasal airway obstruction during the preoperative assessment. (4) The surgeon, or the surgeon’s designee, should educate rhinoplasty candidates regarding what to expect after surgery, how surgery might affect the ability to breathe through the nose, potential complications of surgery, and the possible need for future nasal surgery. (5) The clinician, or the clinician’s designee, should counsel rhinoplasty candidates with documented obstructive sleep apnea about the impact of surgery on nasal airway obstruction and how obstructive sleep apnea might affect perioperative management. (6) The surgeon, or the surgeon’s designee, should educate rhinoplasty patients before surgery about strategies to manage discomfort after surgery. (7) Clinicians should document patient satisfaction with their nasal appearance and with their nasal function at a minimum of 12 months after rhinoplasty.The guideline development group made recommendations against certain actions: (1) When a surgeon, or the surgeon’s designee, chooses to administer perioperative antibiotics for rhinoplasty, he or she should not routinely prescribe antibiotic therapy for a duration >24 hours after surgery. (2) Surgeons should not routinely place packing in the nasal cavity of rhinoplasty patients (with or without septoplasty) at the conclusion of surgery.The panel group made the following statement an option: (1) The surgeon, or the surgeon’s designee, may administer perioperative systemic steroids to the rhinoplasty patient.
Clinical Practice Guideline: Bell's Palsy Executive Summary
Baugh, Reginald F. , Basura, Gregory J. , Ishii, Lisa E. , Schwartz, Seth, Drumheller, Caitlin, Burkholder, Rebecca, Deckard, Nathan A. , Dawson, Cindy , Driscoll, Colin L. W., Gillespie, M. Boyd , Gurgel, Richard K. , Halperin, John , Kumar, Kaparaboyna Ashok, Micco, Alan G. , Munsell, Debra, Rosenbaum, Steven, Vaughan, William, Gurgel, Richard Klaus , Khalid, Ayesha N.

Otolaryngology–Head and Neck Surgery | November 4, 2013 | Volume: 149 | Issue: 5 | Pages: 656-663

10.1177/0194599813506835 Get It

The American Academy of Otolaryngology—Head and Neck Surgery Foundation (AAO‐HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Bell's Palsy. To assist in implementing the guideline recommendations, this article summarizes the rationale, purpose, and key action statements. The 11 recommendations developed encourage accurate and efficient diagnosis and treatment and, when applicable, facilitate patient follow‐up to address the management of long‐term sequelae or evaluation of new or worsening symptoms not indicative of Bell's palsy. There are myriad treatment options for Bell's palsy; some controversy exists regarding the effectiveness of several of these options, and there are consequent variations in care. In addition, there are numerous diagnostic tests available that are used in the evaluation of patients with Bell's palsy. Many of these tests are of questionable benefit in Bell's palsy. Furthermore, while patients with Bell's palsy enter the health care system with facial paresis/paralysis as a primary complaint, not all patients with facial paresis/paralysis have Bell's palsy. It is a concern that patients with alternative underlying etiologies may be misdiagnosed or have an unnecessary delay in diagnosis. All of these quality concerns provide an important opportunity for improvement in the diagnosis and management of patients with Bell's palsy.
Clinical Practice Guideline: Bell's Palsy
Baugh, Reginald F. , Basura, Gregory J. , Ishii, Lisa E. , Schwartz, Seth, Drumheller, Caitlin, Burkholder, Rebecca, Deckard, Nathan A. , Dawson, Cindy , Driscoll, Colin L. W., Gillespie, M. Boyd , Gurgel, Richard K. , Halperin, John , Kumar, Kaparaboyna Ashok, Micco, Alan G. , Munsell, Debra, Rosenbaum, Steven, Vaughan, William, Gurgel, Richard Klaus , Khalid, Ayesha N.

Otolaryngology–Head and Neck Surgery | November 4, 2013 | Volume: 149 | Issue: S3 | Pages: No page available

10.1177/0194599813505967 Get It

Objective Bell's palsy, named after the Scottish anatomist, Sir Charles Bell, is the most common acute mono‐neuropathy, or disorder affecting a single nerve, and is the most common diagnosis associated with facial nerve weakness/paralysis. Bell's palsy is a rapid unilateral facial nerve paresis (weakness) or paralysis (complete loss of movement) of unknown cause. The condition leads to the partial or complete inability to voluntarily move facial muscles on the affected side of the face. Although typically self‐limited, the facial paresis/paralysis that occurs in Bell's palsy may cause significant temporary oral incompetence and an inability to close the eyelid, leading to potential eye injury. Additional long‐term poor outcomes do occur and can be devastating to the patient. Treatments are generally designed to improve facial function and facilitate recovery. There are myriad treatment options for Bell's palsy, and some controversy exists regarding the effectiveness of several of these options, and there are consequent variations in care. In addition, numerous diagnostic tests available are used in the evaluation of patients with Bell's palsy. Many of these tests are of questionable benefit in Bell's palsy. Furthermore, while patients with Bell's palsy enter the health care system with facial paresis/paralysis as a primary complaint, not all patients with facial paresis/paralysis have Bell's palsy. It is a concern that patients with alternative underlying etiologies may be misdiagnosed or have unnecessary delay in diagnosis. All of these quality concerns provide an important opportunity for improvement in the diagnosis and management of patients with Bell's palsy. Purpose The primary purpose of this guideline is to improve the accuracy of diagnosis for Bell's palsy, to improve the quality of care and outcomes for patients with Bell's palsy, and to decrease harmful variations in the evaluation and management of Bell's palsy. This guideline addresses these needs by encouraging accurate and efficient diagnosis and treatment and, when applicable, facilitating patient follow‐up to address the management of long‐term sequelae or evaluation of new or worsening symptoms not indicative of Bell's palsy. The guideline is intended for all clinicians in any setting who are likely to diagnose and manage patients with Bell's palsy. The target population is inclusive of both adults and children presenting with Bell's palsy. Action Statements The development group made a strong recommendation that (a) clinicians should assess the patient using history and physical examination to exclude identifiable causes of facial paresis or paralysis in patients presenting with acute‐onset unilateral facial paresis or paralysis, (b) clinicians should prescribe oral steroids within 72 hours of symptom onset for Bell's palsy patients 16 years and older, (c) clinicians should not prescribe oral antiviral therapy alone for patients with new‐onset Bell's palsy, and (d) clinicians should implement eye protection for Bell's palsy patients with impaired eye closure. The panel made recommendations that (a) clinicians should not obtain routine laboratory testing in patients with new‐onset Bell's palsy, (b) clinicians should not routinely perform diagnostic imaging for patients with new‐onset Bell's palsy, (c) clinicians should not perform electrodiagnostic testing in Bell's palsy patients with incomplete facial paralysis, and (d) clinicians should reassess or refer to a facial nerve specialist those Bell's palsy patients with (1) new or worsening neurologic findings at any point, (2) ocular symptoms developing at any point, or (3) incomplete facial recovery 3 months after initial symptom onset. The development group provided the following options : (a) clinicians may offer oral antiviral therapy in addition to oral steroids within 72 hours of symptom onset for patients with Bell's palsy, and (b) clinicians may offer electrodiagnostic testing to Bell's palsy patients with complete facial paralysis. The development group offered the following no recommendations : (a) no recommendation can be made regarding surgical decompression for patients with Bell's palsy, (b) no recommendation can be made regarding the effect of acupuncture in patients with Bell's palsy, and (c) no recommendation can be made regarding the effect of physical therapy in patients with Bell's palsy.