Citations 1
Unusual Increased Blood Pool Activity on 68Ga-DOTATATE PET/CT in a Patient With Metastatic Neuroendocrine Disease
Sharma, Akash, Navaz, Anem J., Pandey, Mukesh K., Parent, Ephraim E., Pandey, Mukesh K. , Pandey, Mukesh K , Sharma, Akash, Navaz, Anem J., Pandey, Mukesh K., Parent, Ephraim E.
Clinical Nuclear Medicine | October 25, 2021 | Volume: 47 | Issue: 2 | Pages: 137-139
Abstract 68Ga-DOTATATE is a well-established, positron-emitting, somatostatin receptor–binding radiopharmaceutical. We present an unusual case of transiently increased blood pool uptake of 68Ga-DOTATATE in a patient with well-differentiated stage IV neuroendocrine tumor, with Ki-67 <2% (WHO grade 1) maintained on lanreotide. During serial 68Ga-DOTATATE PET/CT examinations, increased blood pool accumulation of presumably unbound 68Ga was demonstrated, which could impact the Kenning score and lead to a false treatment response assessment.