Citations 2
Acquired peripheral nerve injuries associated with severe COVID-19
Franz, Colin K. , Murthy, Nikhil K. , Malik, George R. , D’Andrea, Dom, Wolfe, Alexis R. , Stearns, Melanie , Deshmukh, Swati , Tavee, Jinny , Sun, Fang , Swong, Kevin , Rydberg, Leslie , Wolfe, Lisa F. , Rogers, John A. , Franz, Colin K , Kwak, Jean Won , Farr, Ellen , Cotton, Ronald James , Walter, James McCauley , Coleman, John M.
No container title available | May 17, 2022 | Volume: No volume available | Issue: No issue available | Pages: No page available
Abstract We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine our latest data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting.
Diaphragm dysfunction in severe COVID‐19 as determined by neuromuscular ultrasound
Farr, Ellen , Wolfe, Alexis R. , Deshmukh, Swati , Rydberg, Leslie , Soriano, Rachna, Boon, Andrea J. , Wolfe, Lisa F. , Franz, Colin K. , Franz, Colin K , Walter, James McCauley
Annals of Clinical and Translational Neurology | July 11, 2021 | Volume: 8 | Issue: 8 | Pages: 1745-1749
Abstract Many survivors from severe coronavirus disease 2019 (COVID‐19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post‐COVID‐19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end‐expiration) for the post‐COVID‐19 compared to non‐COVID‐19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post‐COVID‐19.