Citations 1
Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion
Burton, Kevin M., Cao, Hong , Krueger, Eugene W. , Johnson, Katherine M. , Zhang, Lizhi , McNiven, Mark A. , Razidlo, Gina L. , Qiang, Li , Razidlo, Gina L , Burton, Kevin M., Chen, Jing, Li, Qiang , Johnson, Katherine M., Bamlet, William R.
Molecular Biology of the Cell | May 18, 2020 | Volume: 31 | Issue: 6 | Pages: 439-451
Dyn2 and α-actinin 4 interact directly to regulate invasive cell migration and the stabilization of invadopodia. Intriguingly, this is specific for α-actinin 4, and not the highly related protein α-actinin 1. These findings elucidate a novel mechanism of regulating cell migration, with important implications for invasive tumor cells.