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Yamaguchi, Yu

0000-0003-0098-281X

Mayo Clinic

Sanford Burnham Prebys Medical Discovery Institute

Citations 1

Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease
Liu, Chia‐Chen , Zhao, Na , Cirrito, John R. , Kanekiyo, Takahisa , Bu, Guojun , Yamaguchi, Yu , Holtzman, David M. , Liu, Chia-Chen , Bu, Guojun , Zhao, Na

Science Translational Medicine | March 30, 2016 | Volume: 8 | Issue: 332 | Pages: No page available

10.1126/scitranslmed.aad3650 Get It

Deleting neuronal heparan sulfates in a mouse model of Alzheimer’s disease results in faster Aβ clearance, reduced Aβ aggregation, and less amyloid pathology.