Citations 1
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis
Choi, Jinkuk , Gao, Jie , Kim, Jaekwang , Kim, Jungsu , Tontonoz, Peter , Hong, Cynthia , Kim, Jungsu
Science Translational Medicine | November 18, 2015 | Volume: 7 | Issue: 314 | Pages: No page available
Inhibiting the E3 ubiquitin ligase Idol in a mouse model of Alzheimer’s-like pathology ameliorates disease severity by promoting clearance of Aβ peptides by microglia.