Citations 4
Application of a Clinical‐Electrophysiological Model for Identifying Chronic Inflammatory Demyelinating Polyradiculoneuropathy in an Australian Cohort
Swart, Grace , Garg, Nidhi , Yiannikas, Con , POLLARD, JOHN D., Silsby, Matthew , Spies, Judith, Kiernan, Matthew C, Park, Susanna B. , Skolka, Michael P , Vucic, Steve , Silsby, Matthew , Klein, Christopher J , Skolka, Michael, Carroll, Antonia , Spies, Judith , Kiernan, Matthew C. , Klein, Christopher J.
Journal of the Peripheral Nervous System | May 12, 2026 | Volume: 31 | Issue: 2 | Pages: No page available
Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis
Wainger, Brian J. , McIlduff, Courtney, Maragakis, Nicholas J. , Bedlack, Richard , Goyal, Namita , Rutkove, Seward B. , Lange, Dale J. , Rivner, Michael H. , Goutman, Stephen A. , Mauricio, Elizabeth A. , Baloh, Robert H. , Simmons, Zachary , Pothier, Lindsay , Kassis, Sylvia Baedorf , La, Thuong, Hall, Meghan, Evora, Armineuza, Klements, David , Hurtado, Aura, Pereira, João D. , Koh, Joan, Celnik, Pablo , Chaudhry, Vinay , Gable, Karissa , Juel, Vern C. , Phielipp, Nicolás , Marei, Adel, Rosenquist, Peter B. , Oskarsson, Björn , Lewis, Richard A. , Kaur, Divpreet, Kiskinis, Evangelos , Eggan, Kevin , Weiss, Michael D. , David, William S., Davila-Pérez, Paula , Camprodon, Joan A. , Kiernan, Matthew C. , Atassi, Nazem , Cudkowicz, Merit , Goutman, Stephen A , Simmons, Zachary , Oskarsson, Björn , Maragakis, Nicholas , Bedlack, Richard S , Cudkowicz, Merit E , Kiernan, Matthew C , Macklin, Eric A. , Vucic, Steve , Paganoni, Sabrina , Ladha, Shafeeq , Mauricio, Elizabeth A. , Puerto, Aura Maria Hurtado , Meehan, Sean K. , Woolf, Clifford J. , Berry, James D. , Pascual‐Leone, Álvaro , Shefner, Jeremy M.
JAMA Neurology | November 23, 2020 | Volume: 78 | Issue: 2 | Pages: 186
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS
Andrews, Jinsy , Genge, Angela , Jackson, Carlayne E. , Miller, Timothy M. , Cockroft, Bettina M., Meng, Lisa , Wei, Jenny , Wolff, Andrew A. , Malik, Fady I. , Bodkin, Cynthia, Dionne, Annie , Fee, Dominic B. , Goutman, Stephen A. , Goyal, Namita , Hardiman, Orla , Hayat, Ghazala , Heiman‐Patterson, Terry , Heitzman, Daragh, Johnston, Wendy , Kiernan, Matthew C. , Korngut, Lawrence , Matte, Geneviève, Mora, Jesús S., Needham, Merrilee , Oskarsson, Björn , Pattee, Gary L. , Pulley, Michael , Quan, Dianna , Rezania, Kourosh , Schellenberg, Kerri , Schultz, David , Shoesmith, Christen , Simmons, Zachary , Statland, Jeffrey , Sultan, Shumaila, Weiss, Michael D. , Whyte-Rayson, Ashley, Wymer, James , Zinman, Lorne , Rudnicki, Stacy A. , Oskarsson, Björn , Schellenberg, Kerri L , Goutman, Stephen A , Simmons, Zachary , Hardiman, Orla , Kiernan, Matthew C , Shefner, Jeremy M. , Lechtzin, Noah , Brooks, Benjamin Rix , Caress, James B. , Henderson, Robert D. , Karam, Chafic , Kolb, Stephen J. , Ladha, Shafeeq , Pioro, Erik P. , Swenson, Andrea , Berg, Leonard H. van den , Vu, Tuan , Vucic, Steve
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration | September 24, 2020 | Volume: 22 | Issue: 3-4 | Pages: 287-299
Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score
Kunchok, Amy , Lechner‐Scott, Jeannette , Granella, Franco, Alroughani, Raed , Sola, Patrizia , Lugaresi, Alessandra , Izquierdo, Guillermo , Grammond, Pierre , Sánchez-Menoyo, José Luis , Wijmeersch, Bart Van , Boz, Cavit , Grand’Maison, François , Spitaleri, Daniele , Hupperts, Raymond , Group, for the MSBase Study, Alroughani, Raed , Sormani, Maria P , Pittock, Sean J , Trojano, María , Ferraro, Diana , ONOFRJ, MARCO C. , Özakbaş, Serkan , Pucci, Eugenio , McCombe, Pamela , Vucic, Steve , Jokubaitis, Vilija , Sormani, Maria Pia , Butzkueven, Helmut , Kalinčík, Tomáš , Group, for the MSBase Study
Multiple Sclerosis Journal | July 8, 2020 | Volume: 27 | Issue: 5 | Pages: 695-705
Background: The magnetic resonance imaging in multiple sclerosis (MAGNIMS) score combines relapses and magnetic resonance imaging (MRI) lesions to predict disability outcomes in relapsing–remitting multiple sclerosis (RRMS) treated with interferon-β. Objective: To validate the MAGNIMS score and extend to other disease-modifying therapies (DMTs). To examine the prognostic value of gadolinium contrast-enhancing (Gd+) lesions. Methods: This RRMS MSBase cohort study ( n = 2293) used a Cox model to examine the prognostic value of relapses, MRI activity and the MAGNIMS score for disability worsening during treatment with interferon-β and three other DMTs. Results: Three new T2 lesions (hazard ratio (HR) = 1.60, p = 0.028) or two relapses (HR = 2.24, p = 0.002) on interferon-β (for 12 months) were predictive of disability worsening over 4 years. MAGNIMS score = 2 (1 relapse and ⩾3 T2 lesions or ⩾2 relapses) was associated with a greater risk of disability worsening on interferon-β (HR = 2.0, p = 0.001). In pooled cohort of four DMTs, similar associations were seen (MAGNIMS score = 2: HR = 1.72, p = 0.001). Secondary analyses demonstrated that the addition of Gd+ to the MAGNIMS did not materially improve its prediction of disability worsening. Conclusion: We have validated the MAGNIMS score in RRMS and extended its application to three other DMTs: 1 relapse and ⩾3 T2 lesions or ⩾2 relapses predicted worsening of disability. Contrast-enhancing lesions did not substantially improve the prognostic score.