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Al Jawish, Manar

Mayo Clinic

Division of Gastroenterology, Department of MedicineMayo Clinic, Jacksonville, Florida, United States.

Citations 1

Esophageal symptom burden remains high and associates with failed swallows after 5 years in patients with ineffective esophageal motility
Koop, Andree , Nimma, Induja R., Avaiya, Kevin , Jawish, Manar Al, Acuna, Einar V., Lacy, Brian E., Koop, Andree H , Al Jawish, Manar, Jawish, Manar Al , Lacy, Brian E.

American Journal of Physiology-Gastrointestinal and Liver Physiology | January 31, 2026 | Volume: 330 | Issue: 3 | Pages: G315-G321

10.1152/ajpgi.00287.2025 Get It

Patients with ineffective esophageal motility continue to experience significant symptoms years after diagnosis. In this survey of 47 patients diagnosed ≥5 years earlier, 45% reported GERD symptoms and 75% reported dysphagia. Greater numbers of failed swallows correlated with worse GERD and dysphagia scores, highlighting the long-term clinical impact of IEM and its association with esophageal symptom burden.