Miller, Sophie A
Mayo Clinic
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Citations 2
Impact of inspiratory muscle training on inspiratory muscle metaboreflex in patients with heart failure with preserved ejection fraction
Miller, Sophie , Hammer, Shane M. , Bruhn, Eric J., Olson, Thomas P., Miller, Sophie A, Smith, Joshua R , Borlaug, Barry A. , Olson, Thomas P. , Smith, Joshua R.
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | July 17, 2026 | Volume: 331 | Issue: 2 | Pages: R283-R290
Heart failure with preserved ejection fraction (HFpEF) is associated with exercise intolerance, with respiratory muscle dysfunction as a contributing factor. Patients with HFpEF have exaggerated cardiovascular responses to respiratory muscle metaboreflex activation. In this study, we determined the impact of inspiratory muscle training (IMT) on the respiratory muscle metaboreflex in HFpEF. We found that 8 wk of IMT improved inspiratory muscle strength and attenuated the respiratory muscle metaboreflex-mediated cardiovascular responses in patients with HFpEF.
Multimorbidity and Peak Oxygen Uptake in Patients Undergoing Cardiac Rehabilitation
Gomes, Pauline Francisca, Chacin‐Suarez, Audry , Miller, Sophie , Olson, Thomas P. , Gomes, Pauline F, Miller, Sophie A, Fischer, Karen M.
JAMA Network Open | February 17, 2025 | Volume: 8 | Issue: 2 | Pages: e2461331
10.1001/jamanetworkopen.2024.61331
This cohort study examines changes in oxygen consumption among patients with multiple morbidities undergoing cardiac rehabilitation.