Back to Authors

Unadkat, Krishna D

0009-0000-6475-2832

Mayo Clinic

Mayo Clinic Alix School of Medicine, Scottsdale, AZ, USA.

Citations 8

Dupuytren's in the Public Eye
Dhupati, Pooja , Kisiel, Sara C. , Unadkat, Krishna , Vansdadia, Sunny , Jeger, Jonathan, Noland, Shelley S. , Unadkat, Krishna D , Vansdadia, Sunny H

Annals of Plastic Surgery | February 13, 2026 | Volume: 96 | Issue: 3 | Pages: 212-217

10.1097/sap.0000000000004670 Get It

Background In 2019, the “Facts on Hand” direct-to-consumer advertising (DTCA) campaign, featuring former NFL quarterback John Elway, was launched to raise awareness of Dupuytren's contracture (DC) and its nonsurgical treatment options. Although DTCA has been shown to influence health care behavior in other specialties, its impact on treatment patterns for hand conditions remains unclear. Methods Google Trends was used to examine the influence of direct-to-consumer advertising (DTCA) on Internet-based information-seeking behavior related to DC. Changes in the proportion of surgical and nonsurgical management of DC were evaluated using 2016–2021 Medicare provider billing claims. Results Search interest in DC peaked during the campaign period, with breakout-level increases (>5000%) for terms such as “John Elway,” “needle aponeurotomy,” and “hand surgeon near me.” Medicare data revealed regionally significant increases in CCH utilization, particularly in the Midwest (+10%) and Northeast (+5%), with corresponding declines in fasciectomy. Regional overlap between increased search activity and shifts in treatment patterns suggests a geographically reinforced campaign effect. Conclusion The “Facts on Hand” campaign was associated with increased public interest in DC and coincided with regionally specific shifts in treatment utilization. Although the campaign emphasized a nonsurgical option, breakout searches for terms such as “hand surgeon near me” and “Dupuytren's surgery” suggest that treatment-specific advertising may have encouraged broader engagement with treatment overall. These findings highlight the potential for DTCA to not only raise awareness of the condition itself but also prompt patients to seek specialist care.
GLP-1 Receptor Agonist–Associated Slimmer's Palsy
Dhupati, Pooja , Kisiel, Sara C. , Unadkat, Krishna , Noland, Shelley S. , Unadkat, Krishna D

Annals of Plastic Surgery | December 19, 2025 | Volume: 96 | Issue: 1 | Pages: 69-74

10.1097/sap.0000000000004570 Get It

Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are increasingly used for weight management and cardiometabolic health. Common peroneal neuropathy (CPN) associated with rapid weight loss is attributed to adipose tissue reduction and subsequent nerve compression at the fibular head. Cases of “Slimmer’s Palsy” have been described in conditions involving rapid weight loss, including anorexia, malignancy, and post-biliary surgery, yet it remains underrecognized as a potential complication of GLP-1RA therapy. This case report describes two nondiabetic patients who developed acute foot drop after losing 14% and 18% of their total body weight over 3–6 months of semaglutide and tirzepatide use, respectively. As use of GLP-1RAs continues to rise, peripheral nerve surgeons should be aware of Slimmer's Palsy as a predictable and treatable complication of rapid weight loss and be prepared to intervene before permanent denervation occurs.
Reimagining Surgical Documentation: Implementing Ambient Artificial Intelligence to Enhance Workflow, Reduce Burnout, and Improve Clinical Communication
Unadkat, Krishna , Dhupati, Pooja , Noland, Shelley S. , Unadkat, Krishna D

Plastic & Reconstructive Surgery | December 16, 2025 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1097/prs.0000000000012725 Get It

Ambient Artificial Intelligence in Hand Surgery: Insights, Pearls, and Pitfalls From Real-World Use
Unadkat, Krishna , Dhupati, Pooja , Noland, Shelley S. , Unadkat, Krishna D

HAND | November 11, 2025 | Volume: 21 | Issue: 3 | Pages: 494-497

10.1177/15589447251389661 Get It

Background: Documentation burden is a major contributor to surgeon burnout, particularly in high-volume outpatient specialties such as hand surgery. These encounters often involve multiple concurrent diagnoses, procedural planning, and longitudinal care. Ambient artificial intelligence (AI) tools, which passively transcribe and summarize clinical encounters in real time, have the potential to streamline note generation and reduce cognitive load. Methods: Following institutional rollout of a commercially available ambient AI tool in early 2025, the system was adopted across all outpatient visits in a hand surgery clinic. Observations were collected regarding workflow adaptation, documentation quality, and perceived cognitive impact. To assess note characteristics, 14 carpal tunnel syndrome visit notes (7 AI-generated and 7 surgeon-written) were compared by word count, Flesch-Kincaid readability score, and inclusion of social and medical history. Results: AI-generated histories were longer and exhibited greater linguistic complexity compared with surgeon-written notes. Surgeon-written assessments were longer, more readable, and more consistent in structure and tone. Social history was documented more frequently in AI-generated notes. All AI-generated assessment and plan sections followed a structured, problem-based format. Conclusions: Ambient AI documentation can support the creation of more structured and contextually rich clinical notes in hand surgery settings. However, successful integration requires active clinician engagement and workflow alignment to balance efficiency with clinical accuracy. These findings highlight both the promise and the practical considerations of incorporating ambient AI into surgical documentation workflows.
Shaping the Future of Plastic Surgery: Training and Career Paths of Residency Program Directors
Unadkat, Krishna , Goode, Micah, Payne, Camryn, Noland, Shelley S. , Unadkat, Krishna D , Dhupati, Pooja , Payne, Camryn, Oleru, Olachi O.

Plastic and Reconstructive Surgery - Global Open | September 26, 2025 | Volume: 13 | Issue: S5 | Pages: 33-33

10.1097/01.gox.0001168652.00442.e1 Get It

Glucagon-like Peptide-1 Receptor Agonist Therapy Is Associated With Fewer Medical Complications After Carpal Tunnel Release in Diabetic Patients
Hiredesai, Annika N. , Howlett, Carina P., Kisiel, Sara C. , Unadkat, Krishna , Verhey, Jens T. , Renfree, Kevin J. , Noland, Shelley S. , Renfree, Kevin , Unadkat, Krishna D , Howlett, Carina P.

HAND | July 16, 2025 | Volume: 21 | Issue: 6 | Pages: 922-929

10.1177/15589447251350181 Get It

Background: Diabetic patients experience carpal tunnel syndrome (CTS) at high rates, have increased symptom severity, and experience prolonged recovery after carpal tunnel release (CTR). This study assessed the association of glucagon-like peptide-1 receptor agonist (GLP-1) therapy with postoperative outcomes after CTR in type II diabetic patients with CTS. Methods: Using the PearlDiver database, 25 229 diabetic patients with CTS who underwent CTR and were prescribed GLP-1 therapy were identified and exact matched to 25 229 controls based on age, sex, Elixhauser comorbidity index, tobacco use, obesity, hypothyroidism, and body mass index where available. Demographic variables and comorbidities were compared between groups using Kruskal-Wallis analyses for continuous variables and chi-square tests for categorical variables. Bivariate logistic regression analysis was conducted for 90-day outcomes and 2-year CTR revision. Results: Patients on GLP-1 therapy had decreased risk of 90-day medical complications (odds ratio [OR] = 0.90; 95% confidence interval [CI], 0.84-0.96) and hospital readmission (OR = 0.85; 95% CI, 0.77-0.94) of 0.5% and 0.4%, respectively, compared with controls. No significant differences were found in 90-day surgical complications or 2-year revision rates between cohorts. There were no cases of aspiration pneumonia. The GLP-1 cohort had increased odds of higher 90-day total costs of care (OR = 2.42; 95% CI, 1.88-3.15). Conclusions: GLP-1 therapy is associated with reduced risk of 90-day medical complications and hospital readmission following CTR in diabetic patients, suggesting these medications may optimize comorbidity profiles via glucose control preoperatively. Future studies may examine whether GLP-1 therapy is associated with minimum clinically important difference in patient-reported outcome measures for CTS in diabetic patients.
68. The Use of Spino-plastic Surgery in Patients With Complex Spinal Reconstructive Needs: An Initial Cohort And Associated Outcomes
Reece, Edward M., Buchanan, D., Unadkat, Krishna , Vernik, Daniel M. , Jeger, Jonathan L. , Spronsen, Nicole R. Van, Meyer, Jenna H., Kalani, Maziyar A. , Unadkat, Krishna D , Jungbauer, Walter N , Buchanan, Dylon C., Jeger, Jonathan L , Spronsen, Nicole Van

Plastic and Reconstructive Surgery - Global Open | April 25, 2025 | Volume: 13 | Issue: S1 | Pages: 46-47

10.1097/01.gox.0001112224.42767.e4 Get It

Is Artificial Intelligence the Future of Radiology? Accuracy of ChatGPT in Radiologic Diagnosis of Upper Extremity Bony Pathology
Hiredesai, Annika N. , Martínez, Christian , Anderson, Megan L. , Howlett, Carina P., Unadkat, Krishna , Noland, Shelley S. , Martinez, Casey , Martinez, Casey J, Unadkat, Krishna D , Anderson, Megan L. , Howlett, Carina P.

HAND | December 6, 2024 | Volume: 21 | Issue: 1 | Pages: 73-80

10.1177/15589447241298982 Get It

Background: Artificial intelligence (AI) is a promising tool to aid in diagnostic accuracy and patient communication. Prior literature has shown that ChatGPT answers medical questions and can accurately diagnose surgical conditions. The purpose of this study was to determine the accuracy of ChatGPT 4.0 in evaluating radiologic imaging of common orthopedic upper extremity bony pathologies, including identifying the imaging modality and diagnostic accuracy. Methods: Diagnostic imaging was sourced from an open-source radiology database for 6 common upper extremity bony pathologies: distal radius fracture (DRF), metacarpal fracture (MFX), carpometacarpal osteoarthritis (CMC), humerus fracture (HFX), scaphoid fracture (SFX), and scaphoid nonunion (SN). X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) modalities were included. Fifty images were randomly selected from each pathology where possible. Images were uploaded to ChatGPT 4.0 and queried for imaging modality, laterality, and diagnosis. Each image query was completed in a new ChatGPT search tab. Multinomial linear regression was used to identify variations in ChatGPT’s diagnostic accuracy across imaging modalities and medical conditions. Results: Overall, ChatGPT provided a diagnosis for 52% of images, with accuracy ranging from 0% to 55%. Diagnostic accuracy was significantly lower for SFX and MFX relative to HFX. ChatGPT was significantly less likely to provide a diagnosis for MRI relative to CT. Diagnostic accuracy ranged from 0% to 40% with regard to imaging modality (x-ray, CT, MRI) though this difference was not statistically significant. Conclusions: ChatGPT’s accuracy varied significantly between conditions and imaging modalities, though its iterative learning capabilities suggest potential for future diagnostic utility within hand surgery.