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Buser, Zorica

0000-0002-5680-0643

Mayo Clinic

Department of Orthopaedic Surgery, NYU Grossman School of Medicine, New York, NY, USA.

Citations 3

Response to Letter to the Editor Regarding “New-Onset Psychiatric Disorders After Lumbar Fusion: Predictors, Timing, and Risk Stratification”
Ballatori, Alexander M. , Ton, Andy , Chen, Xiao T. , Buser, Zorica , Wang, Jeffrey, Ton, Andy , Buser, Zorica , Shahrestani, Shane

Global Spine Journal | February 3, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.1177/21925682251414155 Get It

New-Onset Psychiatric Disorders After Lumbar Fusion: Predictors, Timing, and Risk Stratification
Ballatori, Alexander M. , Ton, Andy , Chen, Xiao T. , Buser, Zorica , Wang, Jeffrey , Ton, Andy , Buser, Zorica , Shahrestani, Shane

Global Spine Journal | November 17, 2025 | Volume: 16 | Issue: 5 | Pages: 2212-2219

10.1177/21925682251400284 Get It

Study Design Retrospective cohort study using a nationally representative inpatient database. Objective To determine the incidence, timing, and predictors of new-onset psychiatric disorders following lumbar fusion surgery, and to propose a data-driven risk stratification model for early identification and intervention. Methods We queried the Nationwide Readmissions Database (2016-2019) to identify adults undergoing elective inpatient lumbar fusion. Patients with preexisting psychiatric diagnoses were excluded. Outcomes included new-onset depression, anxiety, suicidal ideation, and homicidal ideation within 12 months postoperatively. Predictors were assessed using odds ratios. Timing of onset was evaluated with density plots. Results Among 839,576 patients, 12,011 developed depression, 11,828 anxiety, 916 suicidal ideation, and 63 homicidal ideation. Most diagnoses occurred within 90 days postoperatively, with peak incidence around 3 weeks. Opioid use during the index admission significantly increased odds of suicidal ideation (OR 2.13, P = 0.001), anxiety (OR 1.26, P = 0.002), and showed a trend toward depression (OR 1.14, P = 0.087). Medicaid insurance was the strongest predictor of suicidal (OR 3.69) and homicidal ideation (OR 6.41). Female sex and younger age were associated with anxiety and depression; older age was protective against ideation. Conclusions New-onset psychiatric disorders are a frequent and early complication following lumbar fusion. Several modifiable and demographic factors - including perioperative opioid use and socioeconomic status - significantly predict risk. These findings underscore the need for structured mental health screening within the first 3 months post-surgery. Implementing a predictive risk stratification tool could enable earlier psychiatric referral, reduce long-term morbidity, and improve both recovery trajectories and overall quality of life.
The Influence of Hospital Type, Insurance Type, and Patient Income on 30-Day Complication and Readmission Rates Following Lumbar Spine Fusion
Chen, Matthew , Ton, Andy , Chen, Xiao, Ballatori, Alexander M. , Wang, Jeffrey C. , Buser, Zorica , Buser, Zorica , Ton, Andy , Shahrestani, Shane , Chen, Xiao

Global Spine Journal | December 16, 2023 | Volume: 15 | Issue: 2 | Pages: 1061-1067

10.1177/21925682231222903 Get It

Background Context Several studies have shown that factors such as insurance type and patient income are associated with different readmission rates following certain orthopaedic procedures. The literature, however, remains sparse with regard to these demographic characteristics and their associations to perioperative lumbar spine fusion outcomes. Purpose The purpose of this study was to assess the associations between hospital type, insurance type, and patient median income to both 30-day complication and readmission rates following lumbar spine fusion. Patient Sample Patients who underwent primary lumbar spine fusion (n = 596,568) from 2010-2016 were queried from the National Readmissions Database (NRD). Outcome Measures Incidence of 30-day complication and readmission rates Methods All relevant diagnoses and procedures were identified using International Classification of Disease, 9th and 10th Edition (ICD-9, 10) codes. Hospital types were categorized as metropolitan non-teaching (n = 212,131), metropolitan teaching (n = 364,752), and rural (n = 19,685). Insurance types included: Medicare (n = 213,534), Medicaid (n = 78,520), private insurance (n = 196,648), and out-of-pocket (n = 45,025). Patient income was divided into the following quartiles: Q1 (n = 112,083), Q2 (n = 145,755), Q3 (n = 156,276), and Q4 (n = 147,289), wherein quartile 1 corresponded to lower income ranges and quartile 4 to higher ranges. Statistical analysis was conducted in R. Kruskal-Wallis tests with Dunn’s pairwise comparisons were performed to analyze differences in 30-day readmission and complication rates in patients who underwent lumbar spine fusion. Complications analyzed included infection, wound injury, hematoma, neurological injury, thromboembolic event, and hardware failure. Results 30-day readmission was significantly higher in metropolitan teaching hospitals compared to metropolitan non-teaching hospitals and rural hospitals ( P < .05). Patients from metropolitan teaching hospitals had significantly higher rates of infection ( P < .001), wound injury ( P < .001), hematoma ( P = .018), and hardware failure ( P < .002) compared to those treated at metropolitan non-teaching hospitals. Privately insured patients were significantly less likely to be readmitted at 30 days than those paying with Medicare or Medicaid ( P < .01). Patients with private insurance also experienced significantly lower rates of hematoma formation than Medicare beneficiaries and out-of-pocket payers ( P < .01), postoperative wound injury compared to Medicaid patients and out-of-pocket payers ( P < .005), and infection compared to all other groups ( P < .001). Patients in Quartile 4 experienced significantly greater rates of hematoma formation compared to those in Quartiles 1 and 2 and were more likely to experience a thromboembolic event compared to all other groups. Conclusion Patients undergoing lumbar spine fusion at metropolitan non-teaching hospitals and paying with private insurance had significantly lower 30-day readmission rates than their counterparts. Complications within 30 days following lumbar spine fusion were significantly higher in patients treated at metropolitan teaching hospitals and in Medicare and Medicaid beneficiaries. Aside from a few exceptions, however, patient income was generally not associated with differential complication rates.