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Shaikh, Marwan E

Mayo Clinic

Mayo Clinic, Jacksonville, FL, USA.

Citations 3

Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis
Wolf, Emily, Li, David, Fernandez, Andre, Gardner, Lindsay B., Rivera, Candido E., Wysokinska, Ewa , Shaikh, Marwan , Moustafa, Muhamad Alhaj , Wolf, Emily B , Fernandez, Andre J, Shaikh, Marwan E, Moustafa, Muhamad Alhaj , Tun, Han W. , Roy, Vivek

Journal of Investigative Medicine High Impact Case Reports | November 3, 2023 | Volume: 11 | Issue: No issue available | Pages: No page available

10.1177/23247096231209543 Get It

Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bilateral retinal hemorrhages. The coagulopathy was corrected with the initiation of chemotherapy and subsequent reduction in peripheral blast count.