Gonzalez-Izundegui, Daniel
Mayo Clinic
Precision Medicine for Obesity Program, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Citations 1
Effect of caloric intake and macronutrient composition on intestinal cholesterol absorption and bile acids in patients with obesity
Hashem, Anas , Cifuentes, Lizeth , Ricardo-Silgado, Maria Laura , Gonzalez‐Izundegui, Daniel, Campos, Alejandro , Mcrae, Alison, Franks, Shawna, Burton, Duane, Petterson, Xuan-Mai, Camilleri, Michael , Hashem, Anas Mohamad , Calderon, Gerardo, Gonzalez-Izundegui, Daniel, Hurtado, Maria Daniela , Lanza, Ian R , Camilleri, M , Acosta, Andres , Campos, Alejandro , Calderon-Lopez, Gerardo , Hurtado, Maria D. , Lanza, Ian R. , Acosta, Andrés
American Journal of Physiology-Gastrointestinal and Liver Physiology | June 21, 2022 | Volume: 323 | Issue: 3 | Pages: G157-G164
We show how switching from a regular diet to an HCHF increases cholesterol absorption in patients with normal weight and obesity. The decrease in cholesterol absorption from an HCHF to an LCLF, on the other hand, was only seen in normal-weight controls, underlining the importance of body weight in this regulation. In addition, changes in caloric and fat content had an immediate and direct effect on hepatic bile acid production.