Back to Authors

Mosto, Hugo

0000-0002-7460-1904

Mayo Clinic

Cardiology Department, Ramos Mejia Hospital, Buenos Aires, Argentina (M.A., M.F.S., H.M.).

Citations 1

Pulmonary Congestion During Exercise Stress Echocardiography in Ischemic and Heart Failure Patients
Merli, Elisa , Scali, Maria Chiara, Zagatina, A , Merlo, Pablo , Daros, Clarissa Borguezan , Pretto, José Luis de Castro e Silva , Amor, Miguel , Salamè, Michael, Mosto, Hugo , Reisenhofer, Barbara, Wierzbowska‐Drabik, Karina , Kasprzak, Jarosław D. , Ágoston, Gergely , Varga, Albert , Dodi, Claudio , Cortigiani, Lauro , Simova, Iana , Samardjieva, Martina, Citro, Rodolfo , Čelutkienė, Jelena , Re, Federica , Gligorova, Suzana , Antonini‐Canterin, Francesco, Carpeggiani, Clara , Picano, Eugenio , (SIECVI), on behalf of Stress Echo 2020 and 2030 study group of the Italian Society of Echocardiography and Cardiovascular Imaging, Zagatina, Angela , Merlo, Pablo Martin , Borguezan-Daros, Clarissa , de Castro E Silva Pretto, José Luis , Amor, Miguel , Mosto, Hugo , Morrone, Doralisa , Rodriguez-Zanella, Hugo , Kasprzak, Jaroslaw D , Simova, Iana , Citro, Rodolfo , Monte, Ines , Gligorova, Suzana , Pellikka, Patricia A , Wierzbowska-Drabik, Karina , Celutkiene, Jelena , Ciampi, Quirino , Arbucci, Rosina , Morrone, Doralisa , D’Andrea, Antonello , Rodríguez‐Zanella, Hugo , Lowenstein, Jorge , Monte, Ines , Pepi, Mauro , Pellikka, Patricia A. , (SIECVI), on behalf of Stress Echo 2020 and 2030 study group of the Italian Society of Echocardiography and Cardiovascular Imaging

Circulation: Cardiovascular Imaging | May 17, 2022 | Volume: 15 | Issue: 5 | Pages: No page available

10.1161/circimaging.121.013558 Get It

Background: Lung ultrasound detects pulmonary congestion as B-lines at rest, and more frequently, during exercise stress echocardiography (ESE). Methods: We performed ESE plus lung ultrasound (4-site simplified scan) in 4392 subjects referred for semi-supine bike ESE in 24 certified centers in 9 countries. B-line score ranged from 0 (normal) to 40 (severely abnormal). Five different populations were evaluated: control subjects (n=103); chronic coronary syndromes (n=3701); heart failure with reduced ejection fraction (n=395); heart failure with preserved ejection fraction (n=70); ischemic mitral regurgitation ≥ moderate at rest (n=123). In a subset of 2478 patients, follow-up information was available. Results: During ESE, B-lines increased in all study groups except controls. Age, hypertension, abnormal ejection fraction, peak wall motion score index, and abnormal heart rate reserve were associated with B-lines in multivariable regression analysis. Stress B lines (hazard ratio, 2.179 [95% CI, 1.015–4.680]; P =0.046) and ejection fraction <50% (hazard ratio, 2.942 [95% CI, 1.268–6.822]; P =0.012) were independent predictors of all-cause death (n=29 after a median follow-up of 29 months). Conclusions: B-lines identify the pulmonary congestion phenotype at rest, and more frequently, during ESE in ischemic and heart failure patients. Stress B-lines may help to refine risk stratification in these patients. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT 03049995.