Ristagno, Elizabeth
Mayo Clinic
Department of Pediatric and Adolescent Medicine, Mayo Clinic Minnesota, Rochester, Minnesota, USA.
Citations 2
Antibiotic pretreatment and culture yield in pediatric osteoarticular infection: a systematic review and meta-analysis
Shieb, Mohamad , Decesare, Caroline, Elizabeth, Ristagno, Li, Guyu , Ristagno, Elizabeth, Ristagno, Elizabeth H.
Clinical and Experimental Pediatrics | September 14, 2026 | Volume: No volume available | Issue: No issue available | Pages: No page available
Cryptococcal pneumonia in an adolescent with a gain-of-function variant in signal transduction and activator of transcription 1 (STAT1)
Marinelli, Lisa M. , Ristagno, Elizabeth H. , Abraham, Roshini S. , Joshi, Avni Y. , Ristagno, Elizabeth, Fischer, Philip , Joshi, Avni, Fischer, Philip R.
BMJ Case Reports | April 23, 2020 | Volume: 13 | Issue: 4 | Pages: e234120
An adolescent male with a history of autoimmune enteropathy, autoimmune hypothyroidism, aphthous stomatitis and recurrent oral Candida infections only in the setting of curative antibiotic courses presented with cryptococcal pneumonia and perihilar adenitis, which was successfully treated with antifungal therapy. The patient had a complex history with several immunological anomalies. Whole exome sequencing revealed a known STAT1 pathogenic variant, associated with gain of function (GOF). This case expands our understanding of the broad clinical phenotype manifested by STAT1 GOF and emphasises the importance of consideration of this diagnosis in patients presenting with opportunistic infections and autoimmunity.