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Weygant, Nathaniel

0000-0001-7861-6532

Mayo Clinic

Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.

Citations 2

Role of the Microenvironment in Gastrointestinal Tumors
Weygant, Nathaniel , Ge, Yang , Westphalen, C. Benedikt , Ma, Wen Wee, Weygant, Nathaniel , Wee, Wen , Vega, Kenneth J.

Journal of Oncology | December 11, 2019 | Volume: 2019 | Issue: No issue available | Pages: 1-2

10.1155/2019/2153413 Get It

Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers
Ge, Yang , Westphalen, C. Benedikt , Weygant, Nathaniel , Ma, Wen Wee, Weygant, Nathaniel , Wee, Wen , Vega, Kenneth J.

Journal of Oncology | October 31, 2019 | Volume: 2019 | Issue: No issue available | Pages: 1-11

10.1155/2019/4835318 Get It

Rapid advances in technology are revealing previously unknown organization, cooperation, and limitations within the population of nontumor cells surrounding the tumor epithelium known as the tumor microenvironment (TME). Nowhere are these findings more pertinent than in the gastrointestinal (GI) tract where exquisite cell specialization supports a complex microenvironmental niche characterized by rapid stemness-associated cell turnover, pathogen sensing, epithelial orchestration of immune signaling, and other facets that maintain the complex balance between homeostasis, inflammation, and disease. Here, we summarize and discuss select emerging concepts in the precancerous microenvironment, TME, and tumor epithelial-TME crosstalk as well as their implications for the management of GI cancers.