Peman, J
Mayo Clinic
Unidad de Micología, Servicio de Microbiología, Hospital Universitario La Fe, Valencia, Spain.
Citations 2
Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Met
Espinel‐Ingroff, Ana , Turnidge, John , Alastruey‐Izquierdo, Ana , Castro, C. , Chen, Yee‐Chun , Chen, Yan , Chryssanthou, Erja , Dannaoui, Éric , García‐Effrón, Guillermo , Govender, Nelesh P. , Guinea, Jesús , Kidd, Sarah , Lass‐Flörl, Cornelia , Linares-Sicilia, María José, López-Soria, Leire , Magobo, Rindidzani E. , Peláez, Teresa, Quindós, Guillermo , Rodriguez-Iglesia, M. A., Ruiz, Maite, Sánchez, F , Sanguinetti, Maurizio , Shields, Ryan K. , Szweda, Piotr , Wengenack, Nancy L. , Bramati, Simone, Cavanna, C. , DeLuca, C., Grancini, Anna, Negri, C. E., Passera, Marco, Pemán, Javier , Prigitano, Anna , Sala, E., Tejada, M., Alastruey-Izquierdo, A , Dannaoui, E , Govender, N P , Guinea, J , Quindós, G , Sánchez-Reus, F , Sanguinetti, M , Szweda, P , Tortorano, A , Peman, J , Kidd, Sarah E , Botterel, Françoise , Cantón, Rafael , González, Gloria María , Lackner, Michaela , Pipaón, Maite Ruíz-Pérez de , Gelmi, Maria Luisa , Lombardi, Giuseppe , Meletiadis, Joseph
Antimicrobial Agents and Chemotherapy | October 11, 2018 | Volume: 63 | Issue: 1 | Pages: No page available
Although the Sensititre Yeast-One (SYO) and Etest methods are widely utilized, interpretive criteria are not available for triazole susceptibility testing of Candida or Aspergillus species. We collected fluconazole, itraconazole, posaconazole, and voriconazole SYO and Etest MICs from 39 laboratories representing all continents for (method/agent-dependent) 11,171 Candida albicans , 215 C. dubliniensis , 4,418 C. glabrata species complex, 157 C. guilliermondii ( Meyerozyma guilliermondii ), 676 C. krusei ( Pichia kudriavzevii ), 298 C. lusitaniae ( Clavispora lusitaniae ), 911 C. parapsilosis sensu stricto , 3,691 C. parapsilosis species complex, 36 C. metapsilosis , 110 C. orthopsilosis , 1,854 C. tropicalis , 244 Saccharomyces cerevisiae , 1,409 Aspergillus fumigatus , 389 A. flavus , 130 A. nidulans , 233 A. niger , and 302 A. terreus complex isolates.
Multicenter Study of Epidemiological Cutoff Values and Detection of Resistance in Candida spp. to Anidulafungin, Caspofungin, and Micafungin Using the Sensititre YeastOne Colorimetric Method
Espinel‐Ingroff, Ana , Carver, Peggy L. , Chen, S. C.-A., Eschenauer, Gregory , Getsinger, Diane, Govender, Nelesh P. , Grancini, Anna, Kidd, Sarah , Klinker, Kenneth , Kubin, Christine J. , Morris, Arthur J. , Peláez, Teresa, Quindós, Guillermo , Sánchez, F , Wengenack, Nancy L. , Solé, N. Borrell, Echeverría, J. , Esperalba, Juliana , Pedrosa, E. Gómez-G. de la, Linares, María José Pedraja, Marco, Francesc , Merino, Paloma , Pemán, Javier , Molino, Luisa Pérez del, Mayans, E. Roselló, Calvo, Carmen Rubio, Pipaón, Maite Ruiz Pérez de, Yagüe, Genoveva, García‐Effrón, Guillermo , Guinea, Jesús , Perlin, David S. , Sanguinetti, Maurizio , Shields, Ryan K. , Turnidge, John , Govender, N P , Quindós, G , Guinea, J , Álvarez-Fernández, Maximiliano , Cantón, Rafael , Chen, S. C.- A., González, Gloria María , Hanson, Kimberly E. , Kus, Julianne V. , Lockhart, Shawn R. , Meletiadis, Joseph , Rodríguez‐Iglesias, Manuel , Shoham, Shmuel , Pedrosa, Elia Gómez G. de la , García, Inmaculada García , Sánchez-Reus, F , Sanguinetti, M , Peman, J , Kidd, Sarah E
Antimicrobial Agents and Chemotherapy | August 18, 2015 | Volume: 59 | Issue: 11 | Pages: 6725-6732
ABSTRACTNeither breakpoints (BPs) nor epidemiological cutoff values (ECVs) have been established forCandidaspp. with anidulafungin, caspofungin, and micafungin when using the Sensititre YeastOne (SYO) broth dilution colorimetric method. In addition, reference caspofungin MICs have so far proven to be unreliable.Candidaspecies wild-type (WT) MIC distributions (for microorganisms in a species/drug combination with no detectable phenotypic resistance) were established for 6,007Candida albicans, 186C. dubliniensis, 3,188C. glabratacomplex, 119C. guilliermondii, 493C. krusei, 205C. lusitaniae, 3,136C. parapsilosiscomplex, and 1,016C. tropicalisisolates. SYO MIC data gathered from 38 laboratories in Australia, Canada, Europe, Mexico, New Zealand, South Africa, and the United States were pooled to statistically define SYO ECVs. ECVs for anidulafungin, caspofungin, and micafungin encompassing ≥97.5% of the statistically modeled population were, respectively, 0.12, 0.25, and 0.06 μg/ml forC. albicans, 0.12, 0.25, and 0.03 μg/ml forC. glabratacomplex, 4, 2, and 4 μg/ml forC. parapsilosiscomplex, 0.5, 0.25, and 0.06 μg/ml forC. tropicalis, 0.25, 1, and 0.25 μg/ml forC. krusei, 0.25, 1, and 0.12 μg/ml forC. lusitaniae, 4, 2, and 2 μg/ml forC. guilliermondii, and 0.25, 0.25, and 0.12 μg/ml forC. dubliniensis. Species-specific SYO ECVs for anidulafungin, caspofungin, and micafungin correctly classified 72 (88.9%), 74 (91.4%), 76 (93.8%), respectively, of 81Candidaisolates with identifiedfksmutations. SYO ECVs may aid in detecting non-WT isolates with reduced susceptibility to anidulafungin, micafungin, and especially caspofungin, since testing the susceptibilities ofCandidaspp. to caspofungin by reference methodologies is not recommended.