Singh, Preet P
Mayo Clinic
Department of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USA.
Citations 1
Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia
El‐Haj, Nura , Smeltzer, Jacob P., Gangat, Naseema , Singh, Preet P, Gonsalves, Wilson I. , Gupta, Vinay Kumar , Parikh, Sameer A. , Singh, Preet Paul
Case Reports in Hematology | January 19, 2014 | Volume: 2014 | Issue: No issue available | Pages: 1-4
Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one’s own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency.