Citations 1
Intrathecal Capsaicin Depletes Substance P in the Rat Spinal Cord and Produces Prolonged Thermal Analgesia
Yaksh, Tony L. , Leeman, Susan E. , Jessell, Thomas M., Farb, David H.
Science | October 5, 2006 | Volume: 206 | Issue: 4417 | Pages: 481-483
A single intrathecal injection of capsaicin depletes substance P from primary sensory neurons and causes a prolonged increase in the thermal and chemical pain thresholds of the rat but no apparent change in responses to noxious mechanical stimuli.